Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) | 0.0691 | 1 | 0.5 |
Mycobacterium ulcerans | beta-ketoacyl synthase-like protein | 0.0691 | 1 | 0.5 |
Plasmodium falciparum | beta-ketoacyl-ACP synthase III | 0.0691 | 1 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | 3-oxoacyl-ACP synthase | 0.0691 | 1 | 0.5 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.0691 | 1 | 0.5 |
Mycobacterium ulcerans | 3-oxoacyl-ACP synthase | 0.0691 | 1 | 0.5 |
Trypanosoma brucei | RNA helicase, putative | 0.0215 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0215 | 0 | 0.5 |
Plasmodium vivax | beta-ketoacyl-acyl carrier protein synthase III precursor, putative | 0.0691 | 1 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
IC50 (functional) | = 3.5 uM | Evaluated for the antioxidant property by measuring the inhibition of microsomal lipid peroxidation | ChEMBL. | 11206462 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.