Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | glutamate receptor, metabotropic 5 | Starlite/ChEMBL | References |
Homo sapiens | glutamate receptor, metabotropic 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | lamin | 0.0028 | 0.1211 | 0.1118 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0082 | 0.6358 | 0.6929 |
Brugia malayi | Receptor family ligand binding region containing protein | 0.0025 | 0.0976 | 0.1241 |
Echinococcus multilocularis | lamin | 0.0028 | 0.1211 | 0.1118 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.1211 | 0.1211 |
Echinococcus granulosus | lamin dm0 | 0.0028 | 0.1211 | 0.1118 |
Loa Loa (eye worm) | glutamate receptor | 0.0038 | 0.2245 | 0.2245 |
Loa Loa (eye worm) | receptor family ligand binding region containing protein | 0.0025 | 0.0976 | 0.0976 |
Brugia malayi | metabotropic GABA-B receptor subtype 2 | 0.0016 | 0.0105 | 0.0134 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0028 | 0.1211 | 0.1211 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0976 | 0.0976 |
Brugia malayi | intermediate filament protein | 0.0028 | 0.1211 | 0.1541 |
Brugia malayi | metabotropic glutamate receptor type 2 | 0.0048 | 0.3115 | 0.3963 |
Echinococcus multilocularis | musashi | 0.0028 | 0.1211 | 0.1118 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0098 | 0.7861 | 1 |
Onchocerca volvulus | 0.0028 | 0.1211 | 1 | |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0048 | 0.3115 | 0.3335 |
Schistosoma mansoni | lamin | 0.0028 | 0.1211 | 0.1226 |
Loa Loa (eye worm) | metabotropic GABA-B receptor subtype 2 | 0.0025 | 0.0976 | 0.0976 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 1 | 1 |
Schistosoma mansoni | intermediate filament proteins | 0.0028 | 0.1211 | 0.1226 |
Echinococcus granulosus | intermediate filament protein | 0.0028 | 0.1211 | 0.1118 |
Onchocerca volvulus | 0.0028 | 0.1211 | 1 | |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0111 | 0.9129 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0105 | 0.0105 |
Schistosoma mansoni | lamin | 0.0028 | 0.1211 | 0.1226 |
Loa Loa (eye worm) | glutamate receptor | 0.0098 | 0.7861 | 0.7861 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0089 | 0.699 | 0.8893 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0082 | 0.6358 | 0.6319 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.012 | 1 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0028 | 0.1211 | 0.1211 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0082 | 0.6358 | 0.6319 |
Echinococcus multilocularis | lamin dm0 | 0.0028 | 0.1211 | 0.1118 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.1163 | 0.1163 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0028 | 0.1211 | 0.1541 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.