Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Chlamydia trachomatis | 3'(2'),5'-bisphosphate nucleotidase CysQ | 0.0004 | 0.0016 | 0.5 |
Onchocerca volvulus | Inositol monophosphatase 3 homolog | 0.0004 | 0.0016 | 0.5 |
Mycobacterium leprae | POSSIBLE MONOPHOSPHATASE CYSQ | 0.0004 | 0.0016 | 0.0112 |
Trypanosoma cruzi | inositol polyphosphate 1-phosphatase, putative | 0.0004 | 0.0016 | 0.0099 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.163 | 1 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.163 | 0.1616 |
Giardia lamblia | Hypothetical protein | 0.0004 | 0.0016 | 0.5 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.0206 | 1 | 1 |
Echinococcus granulosus | inositol monophosphatase | 0.0004 | 0.0016 | 0.0016 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.0016 | 0.0016 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.163 | 0.5 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.163 | 0.163 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.163 | 1 |
Brugia malayi | Muscleblind-like protein | 0.0148 | 0.7116 | 0.7116 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.2059 | 0.2059 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0148 | 0.7116 | 0.7116 |
Leishmania major | inositol polyphosphate 1-phosphatase, putative | 0.0004 | 0.0016 | 0.0099 |
Brugia malayi | Inositol-1 | 0.0037 | 0.163 | 0.163 |
Mycobacterium ulcerans | inositol-monophosphatase ImpA | 0.0004 | 0.0016 | 0.0099 |
Mycobacterium ulcerans | monophosphatase | 0.0004 | 0.0016 | 0.0099 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.2059 | 0.2059 |
Echinococcus multilocularis | muscleblind protein | 0.0148 | 0.7116 | 0.7116 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.2059 | 0.2059 |
Trypanosoma brucei | inositol polyphosphate 1-phosphatase, putative | 0.0004 | 0.0016 | 0.0099 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.163 | 1 |
Echinococcus multilocularis | 3'(2'),5' bisphosphate nucleotidase 1 | 0.0004 | 0.0016 | 0.0016 |
Echinococcus granulosus | muscleblind protein | 0.0148 | 0.7116 | 0.7116 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.163 | 0.163 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0.1441 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0004 | 0.0016 | 0.0016 |
Toxoplasma gondii | hypothetical protein | 0.0004 | 0.0016 | 0.0099 |
Echinococcus granulosus | 3'2'5' bisphosphate nucleotidase 1 | 0.0004 | 0.0016 | 0.0016 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.2059 | 0.2059 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.163 | 0.163 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.7116 | 0.7116 |
Trypanosoma cruzi | myo-inositol-1 phosphatase, putative | 0.0004 | 0.0016 | 0.0099 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.163 | 0.163 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.163 | 0.1616 |
Mycobacterium ulcerans | monophosphatase CysQ | 0.0004 | 0.0016 | 0.0099 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.163 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0206 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0004 | 0.0016 | 0.0016 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.163 | 0.1616 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.163 | 0.1616 |
Mycobacterium leprae | Probable monophosphatase | 0.0004 | 0.0016 | 0.0112 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.2059 | 0.2059 |
Echinococcus multilocularis | inositol monophosphatase | 0.0004 | 0.0016 | 0.0016 |
Schistosoma mansoni | hypothetical protein | 0.0004 | 0.0016 | 0.0016 |
Mycobacterium ulcerans | monophosphatase CysQ | 0.0004 | 0.0016 | 0.0099 |
Leishmania major | myo-inositol-1 phosphatase, putative | 0.0004 | 0.0016 | 0.0099 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.2059 | 0.2059 |
Mycobacterium leprae | possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). | 0.0033 | 0.1441 | 1 |
Schistosoma mansoni | myo inositol monophosphatase | 0.0004 | 0.0016 | 0.0016 |
Mycobacterium tuberculosis | Probable monophosphatase | 0.0004 | 0.0016 | 0.0112 |
Schistosoma mansoni | pap-inositol-14-phosphatase | 0.0004 | 0.0016 | 0.0016 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.2059 | 0.2059 |
Echinococcus granulosus | 3-phosphoinositide-dependent protein kinase 1 | 0.0206 | 1 | 1 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.163 | 0.163 |
Mycobacterium tuberculosis | Monophosphatase CysQ | 0.0004 | 0.0016 | 0.0112 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.163 | 1 |
Brugia malayi | Inositol monophosphatase family protein | 0.0004 | 0.0016 | 0.0016 |
Trichomonas vaginalis | AGC family protein kinase | 0.0206 | 1 | 1 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.0206 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0206 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0206 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0206 | 1 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.2059 | 0.2059 |
Echinococcus multilocularis | 3 phosphoinositide dependent protein kinase 1 | 0.0206 | 1 | 1 |
Brugia malayi | Inositol monophosphatase family protein | 0.0004 | 0.0016 | 0.0016 |
Entamoeba histolytica | protein kinase, putative | 0.0206 | 1 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase, putative | 0.0004 | 0.0016 | 0.0099 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.2059 | 0.2059 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.163 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.7116 | 0.7116 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.