Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0012 | 0.1045 | 0.1045 |
Brugia malayi | ecdysteroid receptor | 0.0012 | 0.1045 | 0.1045 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0059 | 1 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.1045 | 0.1045 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0012 | 0.1045 | 0.1045 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.1045 | 0.1045 |
Brugia malayi | nuclear hormone receptor | 0.0012 | 0.1045 | 0.1045 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0012 | 0.1045 | 0.1045 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0012 | 0.1045 | 0.1045 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0012 | 0.1045 | 0.1045 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0059 | 1 | 0.5 |
Brugia malayi | steroid hormone receptor | 0.0012 | 0.1045 | 0.1045 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0012 | 0.1045 | 0.1045 |
Schistosoma mansoni | thyroid hormone receptor | 0.0012 | 0.1045 | 0.1045 |
Trypanosoma brucei | mitogen activated protein kinase 4, putative | 0.0059 | 1 | 0.5 |
Schistosoma mansoni | coup transcription factor | 0.0012 | 0.1045 | 0.1045 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.1045 | 0.1045 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0012 | 0.1045 | 0.5 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.1045 | 0.1045 |
Trypanosoma brucei | protein kinase, putative | 0.0059 | 1 | 0.5 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0059 | 1 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.1045 | 0.1045 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1045 | 0.1045 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0012 | 0.1045 | 0.1045 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0012 | 0.1045 | 0.1045 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.1045 | 0.1045 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0012 | 0.1045 | 0.1045 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0059 | 1 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase | 0.0059 | 1 | 1 |
Echinococcus multilocularis | mitogen activated protein kinase 3 | 0.0059 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1045 | 0.1045 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0012 | 0.1045 | 0.1045 |
Onchocerca volvulus | 0.0012 | 0.1045 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1045 | 0.1045 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0012 | 0.1045 | 0.1045 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0012 | 0.1045 | 0.1045 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0012 | 0.1045 | 0.1045 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0012 | 0.1045 | 0.1045 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0012 | 0.1045 | 0.1045 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0059 | 1 | 0.5 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0012 | 0.1045 | 0.1045 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0012 | 0.1045 | 0.1045 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0012 | 0.1045 | 0.1045 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1045 | 0.1045 |
Brugia malayi | nuclear receptor NHR-88 | 0.0012 | 0.1045 | 0.1045 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1045 | 0.1045 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0012 | 0.1045 | 0.1045 |
Echinococcus granulosus | FTZ F1 alpha | 0.0012 | 0.1045 | 0.1045 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0012 | 0.1045 | 0.1045 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.1045 | 0.1045 |
Loa Loa (eye worm) | CMGC/MAPK/ERK1 protein kinase | 0.0059 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0012 | 0.1045 | 0.1045 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0012 | 0.1045 | 0.1045 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0059 | 1 | 0.5 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0012 | 0.1045 | 0.1045 |
Schistosoma mansoni | thyroid hormone receptor | 0.0012 | 0.1045 | 0.1045 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0012 | 0.1045 | 0.1045 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0012 | 0.1045 | 0.1045 |
Leishmania major | mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 | 0.0059 | 1 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0012 | 0.1045 | 0.1045 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0012 | 0.1045 | 0.1045 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0012 | 0.1045 | 0.1045 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0012 | 0.1045 | 0.1045 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0012 | 0.1045 | 0.1045 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0012 | 0.1045 | 0.1045 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0012 | 0.1045 | 0.1045 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0012 | 0.1045 | 0.1045 |
Trypanosoma cruzi | mitogen activated protein kinase 4, putative | 0.0059 | 1 | 0.5 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.1045 | 0.1045 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0012 | 0.1045 | 0.1045 |
Leishmania major | mitogen activated protein kinase, putative,map kinase, putative | 0.0059 | 1 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0012 | 0.1045 | 0.1045 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0012 | 0.1045 | 0.1045 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0012 | 0.1045 | 0.5 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0012 | 0.1045 | 0.1045 |
Echinococcus granulosus | mitogen activated protein kinase 3 | 0.0059 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0012 | 0.1045 | 0.1045 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1045 | 0.1045 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0059 | 1 | 0.5 |
Trypanosoma cruzi | mitogen activated protein kinase 2, putative | 0.0059 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0012 | 0.1045 | 0.1045 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1045 | 0.1045 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0059 | 1 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor | 0.0012 | 0.1045 | 0.1045 |
Loa Loa (eye worm) | hypothetical protein | 0.0012 | 0.1045 | 0.1045 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0012 | 0.1045 | 0.1045 |
Echinococcus granulosus | mitogen activated protein kinase | 0.0059 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0012 | 0.1045 | 0.1045 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0012 | 0.1045 | 0.5 |
Trypanosoma cruzi | mitogen-activated protein kinase 11, putative | 0.0059 | 1 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0012 | 0.1045 | 0.1045 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.