Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.139 | 0.4304 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.041 | 0.5 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0284 | 0.8378 | 0.8372 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.041 | 0.5 |
Echinococcus granulosus | intermediate filament protein | 0.0058 | 0.1016 | 0.0984 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0126 | 0.3231 | 1 |
Echinococcus multilocularis | lamin dm0 | 0.0058 | 0.1016 | 0.0984 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0171 | 0.0528 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0171 | 0.0136 |
Echinococcus granulosus | lamin dm0 | 0.0058 | 0.1016 | 0.0984 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.004 | 0.041 | 0.0377 |
Onchocerca volvulus | 0.0058 | 0.1016 | 1 | |
Brugia malayi | latrophilin 2 splice variant baaae | 0.007 | 0.139 | 0.4055 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.1016 | 0.3144 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.041 | 0.0292 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0049 | 0.0712 | 0.066 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0032 | 0.0171 | 0.0114 |
Schistosoma mansoni | hypothetical protein | 0.007 | 0.139 | 0.1486 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0032 | 0.0171 | 0.0114 |
Brugia malayi | MH2 domain containing protein | 0.0126 | 0.3231 | 1 |
Brugia malayi | hypothetical protein | 0.004 | 0.041 | 0.0888 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0032 | 0.0171 | 0.0136 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.004 | 0.041 | 0.0292 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0171 | 0.0136 |
Schistosoma mansoni | hypothetical protein | 0.0263 | 0.769 | 0.9162 |
Echinococcus granulosus | lamin | 0.0058 | 0.1016 | 0.0984 |
Onchocerca volvulus | 0.0058 | 0.1016 | 1 | |
Schistosoma mansoni | intermediate filament proteins | 0.0058 | 0.1016 | 0.103 |
Echinococcus multilocularis | musashi | 0.0058 | 0.1016 | 0.0984 |
Schistosoma mansoni | thyroid hormone receptor | 0.0284 | 0.8378 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0102 | 0.2442 | 0.745 |
Schistosoma mansoni | thyroid hormone receptor | 0.0284 | 0.8378 | 1 |
Loa Loa (eye worm) | intermediate filament protein | 0.0058 | 0.1016 | 0.3144 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.2442 | 0.7557 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.0981 | 0.3037 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0712 | 0.2204 |
Echinococcus granulosus | GPCR family 2 | 0.0032 | 0.0171 | 0.0136 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.004 | 0.041 | 0.0377 |
Schistosoma mansoni | lamin | 0.0058 | 0.1016 | 0.103 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0263 | 0.769 | 0.7682 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0102 | 0.2442 | 0.745 |
Schistosoma mansoni | lamin | 0.0058 | 0.1016 | 0.103 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.041 | 0.5 |
Brugia malayi | intermediate filament protein | 0.0058 | 0.1016 | 0.2844 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0035 | 0.0107 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0031 | 0.0135 | 0.0419 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0126 | 0.3231 | 1 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0032 | 0.0171 | 0.0528 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0102 | 0.2442 | 0.7557 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0058 | 0.1016 | 0.3144 |
Entamoeba histolytica | hypothetical protein | 0.004 | 0.041 | 0.5 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0058 | 0.1016 | 0.2844 |
Echinococcus multilocularis | GPCR, family 2 | 0.0032 | 0.0171 | 0.0136 |
Echinococcus multilocularis | lamin | 0.0058 | 0.1016 | 0.0984 |
Echinococcus multilocularis | tumor protein p63 | 0.0334 | 1 | 1 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0263 | 0.769 | 0.7682 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0032 | 0.0171 | 0.0136 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.