Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | expressed conserved protein | 0.0213 | 1 | 1 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0645 | 0.0384 |
Echinococcus granulosus | lamin | 0.0027 | 0.0645 | 0.0384 |
Brugia malayi | hypothetical protein | 0.002 | 0.0271 | 0.4209 |
Schistosoma mansoni | lamin | 0.0027 | 0.0645 | 0.0738 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.012 | 0.5328 | 0.5197 |
Brugia malayi | Doublecortin family protein | 0.002 | 0.0271 | 0.4209 |
Loa Loa (eye worm) | doublecortin family protein | 0.002 | 0.0271 | 0.4209 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0619 | 0.9606 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0645 | 1 |
Schistosoma mansoni | lipoxygenase | 0.0084 | 0.3501 | 0.6387 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0645 | 0.0738 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0645 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0271 | 0.4209 |
Onchocerca volvulus | 0.0027 | 0.0645 | 1 | |
Brugia malayi | hypothetical protein | 0.002 | 0.0271 | 0.4209 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0645 | 1 |
Plasmodium vivax | multidomain scavenger receptor, putative | 0.002 | 0.0271 | 0.5 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0645 | 0.0384 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0645 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0645 | 0.0384 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0271 | 0.4209 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0645 | 1 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0645 | 0.0384 |
Onchocerca volvulus | 0.0027 | 0.0645 | 1 | |
Schistosoma mansoni | lipoxygenase | 0.012 | 0.5328 | 1 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0645 | 1 |
Schistosoma mansoni | lamin | 0.0027 | 0.0645 | 0.0738 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.012 | 0.5328 | 0.5197 |
Plasmodium falciparum | LCCL domain-containing protein | 0.002 | 0.0271 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.