Detailed information for compound 1179522

Basic information

Technical information
  • TDR Targets ID: 1179522
  • Name: (butyl-dimethylazaniumyl)-cyanoboranide
  • MW: 140.034 | Formula: C7H17BN2
  • H donors: 0 H acceptors: 1 LogP: 1.58 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCC[N+]([BH2-]C#N)(C)C
  • InChi: 1S/C7H17BN2/c1-4-5-6-10(2,3)8-7-9/h4-6,8H2,1-3H3
  • InChiKey: QJNNRWWYAGADSH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • (butyl-dimethyl-ammonio)-cyano-boranide
  • (butyl-dimethylammonio)-cyanoboranide
  • (butyl-dimethyl-azaniumyl)-cyano-boranide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus beta LACTamase domain containing family member 0.0035 0.016 0.0224
Echinococcus granulosus geminin 0.018 0.6743 0.9438
Entamoeba histolytica hypothetical protein 0.0035 0.0159 0.5
Echinococcus multilocularis expressed protein 0.0047 0.0683 0.0955
Mycobacterium ulcerans esterase/lipase LipP 0.0035 0.016 0.5
Schistosoma mansoni tar DNA-binding protein 0.0189 0.7145 1
Plasmodium vivax hypothetical protein, conserved 0.0035 0.016 0.2347
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM10, putative 0.0047 0.0683 1
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0035 0.0159 0.0222
Schistosoma mansoni hypothetical protein 0.0035 0.0159 0.0222
Onchocerca volvulus 0.0035 0.016 0.016
Mycobacterium leprae conserved hypothetical protein 0.0035 0.016 0.5
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0593 0.0831
Brugia malayi beta-lactamase 0.0035 0.016 0.0186
Loa Loa (eye worm) hypothetical protein 0.0067 0.1582 0.1838
Loa Loa (eye worm) TAR-binding protein 0.0189 0.7145 0.8297
Loa Loa (eye worm) hypothetical protein 0.0035 0.016 0.0186
Loa Loa (eye worm) hypothetical protein 0.0035 0.016 0.0186
Loa Loa (eye worm) hypothetical protein 0.0035 0.016 0.0186
Entamoeba histolytica hypothetical protein 0.0035 0.0159 0.5
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0035 0.0159 0.0222
Echinococcus multilocularis mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0362 0.0506
Toxoplasma gondii TIM10 family protein, putative 0.0047 0.0683 1
Loa Loa (eye worm) hypothetical protein 0.0035 0.016 0.0186
Toxoplasma gondii mitochondrial import inner membrane translocase subunit TIM10, putative 0.0047 0.0683 1
Brugia malayi Pre-SET motif family protein 0.0222 0.8611 1
Schistosoma mansoni tar DNA-binding protein 0.0189 0.7145 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0189 0.7145 0.8297
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0593 0.0831
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0035 0.016 0.5
Schistosoma mansoni mitochondrial import inner membrane translocase subunit tim10 0.0047 0.0683 0.0955
Leishmania major hypothetical protein, conserved 0.0035 0.016 0.5
Schistosoma mansoni hypothetical protein 0.0067 0.1582 0.2215
Loa Loa (eye worm) RNA binding protein 0.0189 0.7145 0.8297
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0593 0.0831
Echinococcus multilocularis geminin 0.018 0.6743 0.9438
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0593 0.0689
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0362 0.042
Toxoplasma gondii mitochondrial inner membrane translocase subunit TIM17, putative 0.004 0.0362 0.5299
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0362 0.042
Toxoplasma gondii ABC1 family protein 0.0035 0.016 0.2347
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.016 0.5
Schistosoma mansoni tar DNA-binding protein 0.0189 0.7145 1
Trypanosoma brucei hypothetical protein, conserved 0.0035 0.016 0.5
Mycobacterium leprae Probable lipase LipE 0.0035 0.016 0.5
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.016 0.0224
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0035 0.016 0.0186
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0226 0.8794 1
Mycobacterium ulcerans beta-lactamase 0.0035 0.016 0.5
Brugia malayi hypothetical protein 0.0036 0.0187 0.0217
Brugia malayi RNA recognition motif domain containing protein 0.0189 0.7145 0.8297
Brugia malayi hypothetical protein 0.0036 0.0187 0.0217
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0593 0.0689
Entamoeba histolytica hypothetical protein 0.0035 0.0159 0.5
Schistosoma mansoni transcription factor LCR-F1 0.0035 0.0159 0.0222
Loa Loa (eye worm) hypothetical protein 0.0098 0.2982 0.3463
Onchocerca volvulus 0.0035 0.016 0.016
Loa Loa (eye worm) hypothetical protein 0.004 0.0362 0.042
Plasmodium falciparum mitochondrial import inner membrane translocase subunit TIM10, putative 0.0047 0.0683 1
Echinococcus granulosus expressed protein 0.0047 0.0683 0.0955
Loa Loa (eye worm) transport to inner mitochondrial membrane family member 0.0047 0.0683 0.0793
Schistosoma mansoni tar DNA-binding protein 0.0189 0.7145 1
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.016 0.5
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0593 0.0831
Brugia malayi Mitochondrial import inner membrane translocase subunit Tim17 family protein 0.004 0.0362 0.042
Brugia malayi RNA binding protein 0.0189 0.7145 0.8297
Plasmodium vivax mitochondrial import inner membrane translocase subunit TIM23, putative 0.004 0.0362 0.5299
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0593 0.0831
Loa Loa (eye worm) hypothetical protein 0.0035 0.016 0.0186
Echinococcus granulosus tar DNA binding protein 0.0189 0.7145 1
Onchocerca volvulus 0.0035 0.016 0.016
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0593 0.0831
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0098 0.2982 0.3463
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0222 0.8611 1
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.1582 0.1838
Schistosoma mansoni tar DNA-binding protein 0.0189 0.7145 1
Schistosoma mansoni hypothetical protein 0.018 0.6743 0.9438
Schistosoma mansoni hypothetical protein 0.004 0.0362 0.0506
Mycobacterium ulcerans hypothetical protein 0.0035 0.016 0.5
Brugia malayi TAR-binding protein 0.0189 0.7145 0.8297
Brugia malayi hypothetical protein 0.0035 0.0159 0.0185
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0593 0.0831
Loa Loa (eye worm) beta-lactamase 0.0035 0.016 0.0186
Echinococcus multilocularis beta LACTamase domain containing family member 0.0035 0.016 0.0224
Brugia malayi beta-lactamase family protein 0.0035 0.016 0.0186
Brugia malayi beta-lactamase family protein 0.0035 0.016 0.0186
Echinococcus multilocularis tar DNA binding protein 0.0189 0.7145 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0098 0.2982 0.3463
Mycobacterium ulcerans lipase LipD 0.0035 0.016 0.5
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0035 0.016 0.0186
Entamoeba histolytica hypothetical protein 0.0035 0.0159 0.5
Schistosoma mansoni hypothetical protein 0.018 0.6743 0.9438
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0098 0.2982 0.3463
Loa Loa (eye worm) hypothetical protein 0.0035 0.016 0.0186
Brugia malayi Mitochondrial import inner membrane translocase subunit TIM10 0.0047 0.0683 0.0793
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0035 0.016 0.0224

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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