Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.009 | 0.0083 |
Brugia malayi | Cathepsin L-like precursor | 0.0067 | 0.0782 | 0.3021 |
Onchocerca volvulus | 0.0088 | 0.1265 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0782 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0067 | 0.0782 | 0.3021 |
Echinococcus granulosus | cathepsin L | 0.0035 | 0.003 | 0.0022 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0067 | 0.0782 | 0.0776 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0782 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0067 | 0.0782 | 0.3083 |
Onchocerca volvulus | 0.0067 | 0.0782 | 0.5152 | |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0269 | 0.1041 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0782 | 1 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0086 | 0.123 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0067 | 0.0782 | 0.3021 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0782 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0045 | 0.0269 | 0.2141 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0035 | 0.003 | 0.0089 |
Loa Loa (eye worm) | hypothetical protein | 0.0056 | 0.0521 | 0.2043 |
Echinococcus granulosus | cathepsin l1 | 0.0067 | 0.0782 | 0.0776 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0059 | 0.0593 | 0.0586 |
Loa Loa (eye worm) | hypothetical protein | 0.0142 | 0.2521 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Onchocerca volvulus | Cathepsin L homolog | 0.0067 | 0.0782 | 0.5152 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Echinococcus multilocularis | cysteine protease | 0.0067 | 0.0782 | 0.0776 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0067 | 0.0782 | 0.0776 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0088 | 0.1265 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0088 | 0.1265 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0269 | 0.1041 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.009 | 0.033 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0067 | 0.0782 | 0.0776 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Brugia malayi | Kringle domain containing protein | 0.0088 | 0.1265 | 0.4959 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0312 | 0.1211 |
Toxoplasma gondii | kringle domain-containing protein | 0.0088 | 0.1265 | 0.1988 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Toxoplasma gondii | PAN domain-containing protein | 0.0293 | 0.6 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0045 | 0.0269 | 0.0961 |
Echinococcus granulosus | enteropeptidase | 0.0059 | 0.0593 | 0.0586 |
Onchocerca volvulus | Cathepsin F homolog | 0.0067 | 0.0782 | 0.5152 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Brugia malayi | Protein kinase domain containing protein | 0.0088 | 0.1265 | 0.4959 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0782 | 0.589 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0045 | 0.0269 | 0.0961 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.009 | 0.0678 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.1265 | 0.5004 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0059 | 0.0593 | 0.0586 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0101 | 0.157 | 0.6181 |
Leishmania major | hypothetical protein, conserved | 0.0088 | 0.1265 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0782 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0269 | 0.1041 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0045 | 0.0269 | 0.3182 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0067 | 0.0782 | 0.0776 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0088 | 0.1265 | 0.1259 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0067 | 0.0782 | 0.6091 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.009 | 0.049 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0067 | 0.0782 | 0.3083 |
Echinococcus multilocularis | cathepsin L | 0.0035 | 0.003 | 0.0022 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0045 | 0.0269 | 0.2141 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0782 | 1 |
Toxoplasma gondii | PAN domain-containing protein | 0.0293 | 0.6 | 1 |
Brugia malayi | celfurPC protein | 0.0115 | 0.1885 | 0.7445 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Schistosoma mansoni | subfamily S8B unassigned peptidase (S08 family) | 0.0142 | 0.2521 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.009 | 0.0804 |
Brugia malayi | proprotein convertase 2 | 0.0089 | 0.1298 | 0.5092 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.009 | 0.0083 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0782 | 1 |
Echinococcus granulosus | Mastin | 0.0059 | 0.0593 | 0.0586 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0782 | 0.589 |
Echinococcus multilocularis | 0.0115 | 0.1885 | 0.1879 | |
Echinococcus multilocularis | cysteine protease | 0.0067 | 0.0782 | 0.0776 |
Plasmodium vivax | vivapain-2 | 0.0067 | 0.0782 | 0.6091 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.0829 | 0.327 |
Echinococcus granulosus | furin | 0.0142 | 0.2521 | 0.2516 |
Onchocerca volvulus | Cathepsin L homolog | 0.0067 | 0.0782 | 0.5152 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Schistosoma mansoni | hypothetical protein | 0.0088 | 0.1265 | 0.5004 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0069 | 0.0829 | 0.321 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0067 | 0.0782 | 0.6091 |
Brugia malayi | endoprotease bli-4 precursor | 0.0142 | 0.2521 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Brugia malayi | Cathepsin L-like precursor | 0.0045 | 0.0269 | 0.0961 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Trichomonas vaginalis | Clan SB, family S8, subtilisin-like serine peptidase | 0.0086 | 0.123 | 1 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.009 | 0.049 |
Echinococcus granulosus | cysteine protease | 0.0035 | 0.003 | 0.0022 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0312 | 0.0305 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0782 | 0.6091 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0312 | 0.1211 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.003 | 0.0183 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0035 | 0.003 | 0.0089 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0067 | 0.0782 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0088 | 0.1265 | 0.5004 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0067 | 0.0782 | 0.3021 |
Echinococcus multilocularis | neuroendocrine convertase 2 | 0.0089 | 0.1298 | 0.1292 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0782 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0067 | 0.0782 | 0.6091 |
Echinococcus multilocularis | proprotein convertase subtilisin:kexin type 5 | 0.0086 | 0.123 | 0.1224 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0782 | 0.6091 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.009 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0067 | 0.0782 | 0.3021 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0101 | 0.157 | 0.6215 |
Loa Loa (eye worm) | fibroinase | 0.0067 | 0.0782 | 0.3083 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0782 | 0.589 |
Onchocerca volvulus | 0.0067 | 0.0782 | 0.5152 | |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.009 | 0.0678 |
Brugia malayi | Cathepsin L-like precursor | 0.0067 | 0.0782 | 0.3021 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Brugia malayi | Inositol-1 | 0.0037 | 0.009 | 0.0243 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.157 | 0.6215 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0782 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0782 | 0.6091 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0101 | 0.157 | 0.6181 |
Schistosoma mansoni | furin-1 (S08 family) | 0.0062 | 0.0662 | 0.2603 |
Brugia malayi | cathepsin L-like precursor | 0.0045 | 0.0269 | 0.0961 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0067 | 0.0782 | 0.3083 |
Leishmania major | cysteine peptidase A (CPA) | 0.0067 | 0.0782 | 0.589 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0035 | 0.003 | 0.0089 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0067 | 0.0782 | 0.0776 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0067 | 0.0782 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0088 | 0.1265 | 0.1259 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0312 | 0.0305 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.009 | 0.0804 |
Echinococcus granulosus | cathepsin l1 | 0.0045 | 0.0269 | 0.0262 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0312 | 0.0305 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0782 | 0.589 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0782 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0312 | 0.1211 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0782 | 0.3083 |
Onchocerca volvulus | 0.0067 | 0.0782 | 0.5152 | |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0782 | 0.589 |
Onchocerca volvulus | 0.0067 | 0.0782 | 0.5152 | |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0312 | 0.0305 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.009 | 0.033 |
Brugia malayi | Cathepsin L-like precursor | 0.0067 | 0.0782 | 0.3021 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0312 | 0.1132 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0067 | 0.0782 | 0.0776 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0035 | 0.003 | 0.0022 |
Toxoplasma gondii | cathepsin CPL | 0.0067 | 0.0782 | 0.1171 |
Echinococcus granulosus | neuroendocrine convertase 2 | 0.0089 | 0.1298 | 0.1292 |
Loa Loa (eye worm) | endoprotease bli-4 | 0.0142 | 0.2521 | 1 |
Plasmodium vivax | vivapain-2 | 0.0067 | 0.0782 | 0.6091 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Loa Loa (eye worm) | cysteine protease | 0.0067 | 0.0782 | 0.3083 |
Onchocerca volvulus | 0.0067 | 0.0782 | 0.5152 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0067 | 0.0782 | 0.6337 |
Echinococcus granulosus | proprotein convertase subtilisin:kexin type 5 | 0.0086 | 0.123 | 0.1224 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0045 | 0.0269 | 0.1041 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0067 | 0.0782 | 0.6091 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0059 | 0.0593 | 0.233 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.009 | 0.033 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0067 | 0.0782 | 0.3083 |
Entamoeba histolytica | cysteine protease, putative | 0.0067 | 0.0782 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0312 | 0.1211 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0067 | 0.0782 | 0.6091 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0088 | 0.1265 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.009 | 0.0678 |
Brugia malayi | neuroendocrine convertase 1 precursor | 0.0089 | 0.1298 | 0.5092 |
Echinococcus multilocularis | enteropeptidase | 0.0059 | 0.0593 | 0.0586 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0782 | 0.589 |
Onchocerca volvulus | 0.0067 | 0.0782 | 0.5152 | |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0045 | 0.0269 | 0.1938 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.009 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0069 | 0.0829 | 0.327 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0782 | 0.589 |
Giardia lamblia | High cysteine membrane protein Group 2 | 0.0053 | 0.0453 | 0.5 |
Leishmania major | cathepsin L-like protease | 0.0067 | 0.0782 | 0.589 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0035 | 0.003 | 0.0183 |
Onchocerca volvulus | 0.0067 | 0.0782 | 0.5152 | |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0067 | 0.0782 | 0.3083 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0067 | 0.0782 | 1 |
Echinococcus multilocularis | Mastin | 0.0059 | 0.0593 | 0.0586 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Drug uptake (ADMET) | = 1.17 % ID/g | Biodistribution in Kunming mouse blood at 185 kBq, iv after 2 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 1.22 % ID/g | Biodistribution in Kunming mouse blood at 185 kBq, iv after 15 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 1.61 % ID/g | Biodistribution in Kunming mouse bone at 185 kBq, iv after 2 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 1.98 % ID/g | Biodistribution in Kunming mouse blood at 185 kBq, iv after 30 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 2.1 % ID/g | Biodistribution in Kunming mouse bone at 185 kBq, iv after 15 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 2.11 % ID/g | Biodistribution in Kunming mouse spleen at 185 kBq, iv after 15 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 2.13 % ID/g | Biodistribution in Kunming mouse blood at 185 kBq, iv after 60 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 2.25 % ID/g | Biodistribution in Kunming mouse bone at 185 kBq, iv after 30 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 2.41 % ID/g | Biodistribution in Kunming mouse spleen at 185 kBq, iv after 60 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 2.48 % ID/g | Biodistribution in Kunming mouse spleen at 185 kBq, iv after 30 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 2.54 % ID/g | Biodistribution in Kunming mouse lung at 185 kBq, iv after 15 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 2.6 % ID/g | Biodistribution in Kunming mouse spleen at 185 kBq, iv after 2 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 2.98 % ID/g | Biodistribution in Kunming mouse lung at 185 kBq, iv after 30 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 3.17 % ID/g | Biodistribution in Kunming mouse lung at 185 kBq, iv after 60 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 3.7 % ID/g | Biodistribution in Kunming mouse bone at 185 kBq, iv after 60 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 4.42 % ID/g | Biodistribution in Kunming mouse lung at 185 kBq, iv after 2 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 4.68 % ID/g | Biodistribution in Kunming mouse muscle at 185 kBq, iv after 2 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 4.8 % ID/g | Biodistribution in Kunming mouse liver at 185 kBq, iv after 60 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 5.37 % ID/g | Biodistribution in Kunming mouse liver at 185 kBq, iv after 30 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 5.92 % ID/g | Biodistribution in Kunming mouse liver at 185 kBq, iv after 15 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 6.14 % ID/g | Biodistribution in Kunming mouse liver at 185 kBq, iv after 2 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 9.11 % ID/g | Biodistribution in Kunming mouse muscle at 185 kBq, iv after 30 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 9.24 % ID/g | Biodistribution in Kunming mouse muscle at 185 kBq, iv after 15 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 9.25 % ID/g | Biodistribution in Kunming mouse kidney at 185 kBq, iv after 60 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 9.74 % ID/g | Biodistribution in Kunming mouse muscle at 185 kBq, iv after 60 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 11.59 % ID/g | Biodistribution in Kunming mouse kidney at 185 kBq, iv after 30 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 13.02 % ID/g | Biodistribution in Kunming mouse kidney at 185 kBq, iv after 15 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 18.43 % ID/g | Biodistribution in Kunming mouse kidney at 185 kBq, iv after 2 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 24.8 % ID/g | Biodistribution in Kunming mouse heart at 185 kBq, iv after 60 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 28.07 % ID/g | Biodistribution in Kunming mouse heart at 185 kBq, iv after 30 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 33.54 % ID/g | Biodistribution in Kunming mouse heart at 185 kBq, iv after 15 mins by gamma counting | ChEMBL. | 20056551 |
Drug uptake (ADMET) | = 41.9 % ID/g | Biodistribution in Kunming mouse heart at 185 kBq, iv after 2 mins by gamma counting | ChEMBL. | 20056551 |
Stability (ADMET) | = 66.6 % | Stability in mouse plasma at ~3.7 MBq at room temperature after 20.5 mins by HPLC | ChEMBL. | 20056551 |
Stability (ADMET) | = 95 % | Metabolic stability in Kunming mouse heart at 3.7 MBq, iv at 22 mins by HPLC | ChEMBL. | 20056551 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.