Detailed information for compound 1281120

Basic information

Technical information
  • TDR Targets ID: 1281120
  • Name: N-[2-(5,8-dimethoxy-2-oxo-1H-quinolin-3-yl)et hyl]-1-benzofuran-2-carboxamide
  • MW: 392.405 | Formula: C22H20N2O5
  • H donors: 2 H acceptors: 3 LogP: 4.08 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(c2c1nc(O)c(c2)CCNC(=O)c1cc2c(o1)cccc2)OC
  • InChi: 1S/C22H20N2O5/c1-27-17-7-8-18(28-2)20-15(17)11-14(21(25)24-20)9-10-23-22(26)19-12-13-5-3-4-6-16(13)29-19/h3-8,11-12H,9-10H2,1-2H3,(H,23,26)(H,24,25)
  • InChiKey: AQJOZSBVEFLZGH-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-[2-(5,8-dimethoxy-2-oxo-1H-quinolin-3-yl)ethyl]benzofuran-2-carboxamide
  • N-[2-(5,8-dimethoxy-2-oxo-1H-quinolin-3-yl)ethyl]-2-benzofurancarboxamide
  • N-[2-(2-keto-5,8-dimethoxy-1H-quinolin-3-yl)ethyl]benzofuran-2-carboxamide
  • MLS000101567
  • SMR000018515
  • ZINC04032817

Targets

Known targets for this compound

Species Target name Source Bibliographic reference
Homo sapiens aldehyde dehydrogenase 1 family, member A1 Starlite/ChEMBL No references
Influenza A virus Nonstructural protein 1 Starlite/ChEMBL No references
Homo sapiens tumor protein p53 Starlite/ChEMBL No references
Homo sapiens ATPase family, AAA domain containing 5 Starlite/ChEMBL No references
Homo sapiens ataxin 2 Starlite/ChEMBL No references
Homo sapiens ubiquitin specific peptidase 1 Starlite/ChEMBL No references

Predicted pathogen targets for this compound

By orthology
Species Potential target Known druggable target/s Ortholog Group
Leishmania infantum aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum ko:K00128 aldehyde dehydrogenase (NAD+) [EC1.2.1.3], putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Retinal dehydrogenase 1, putative Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core Get druggable targets OG5_139225 All targets in OG5_139225
Schistosoma mansoni aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus aldehyde dehydrogenase mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Neospora caninum hypothetical protein Get druggable targets OG5_126638 All targets in OG5_126638
Toxoplasma gondii aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania donovani aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania mexicana aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase X, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium tuberculosis Probable aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania braziliensis aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Leishmania major aldehyde dehydrogenase, mitochondrial precursor Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Mycobacterium ulcerans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus granulosus tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
Candida albicans aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Schistosoma japonicum Aldehyde dehydrogenase, mitochondrial precursor, putative Get druggable targets OG5_126638 All targets in OG5_126638
Candida albicans Mitochondrial aldehyde dehydrogenase Get druggable targets OG5_126638 All targets in OG5_126638
Echinococcus multilocularis tumor protein p63 Get druggable targets OG5_140038 All targets in OG5_140038
By sequence similarity to non orthologous known druggable targets
Species Potential target Known druggable target Length Alignment span Identity
Mycobacterium tuberculosis Hypothetical protein Nonstructural protein 1   230 aa 202 aa 23.8 %
Mycobacterium tuberculosis Succinate-semialdehyde dehydrogenase [NADP+] dependent (SSDH) GabD1 aldehyde dehydrogenase 1 family, member A1 501 aa 456 aa 33.3 %
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0112 0.2342
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0013 0.001
Echinococcus multilocularis tumor protein p63 0.0408 0.4047 0.4046
Plasmodium vivax importin-beta 2, putative 0.0028 0.0091 0.1465
Brugia malayi Importin beta-1 subunit 0.0028 0.0091 0.0679
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0047 0.0283 0.2116
Entamoeba histolytica kinesin, putative 0.0078 0.0605 1
Brugia malayi hypothetical protein 0.003 0.0112 0.0842
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0013 0.0035
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0047 0.0283 0.0408
Plasmodium vivax kinesin-5 0.0078 0.0605 1
Loa Loa (eye worm) hypothetical protein 0.0101 0.0848 0.2871
Echinococcus granulosus biogenic amine 5HT receptor 0.0379 0.3748 0.545
Entamoeba histolytica hypothetical protein 0.0023 0.0035 0.0538
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0035 1
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0187 0.0185
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0559 1
Leishmania major importin beta-1 subunit, putative 0.0023 0.0035 0.0583
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0473 1
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0187 0.0269
Entamoeba histolytica Ran family GTPase 0.0021 0.0013 0.0171
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0013 0.0171
Plasmodium falciparum kinesin-5 0.0078 0.0605 1
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0013 0.0171
Trypanosoma brucei PAB1-binding protein , putative 0.003 0.0112 0.2342
Loa Loa (eye worm) hypothetical protein 0.006 0.0418 0.1409
Echinococcus multilocularis microtubule associated protein 2 0.0679 0.6875 0.6875
Leishmania major GTP-binding protein, putative 0.0021 0.0013 0.0185
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0073 0.0559 1
Toxoplasma gondii LsmAD domain-containing protein 0.003 0.0112 0.1827
Schistosoma mansoni hypothetical protein 0.0047 0.0283 0.0408
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0065 0.0473 0.047
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0073 0.0559 0.0557
Loa Loa (eye worm) hypothetical protein 0.0148 0.1336 0.4525
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0148 0.1336 0.4525
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0559 0.081
Brugia malayi latrophilin 2 splice variant baaae 0.0101 0.0848 0.6351
Loa Loa (eye worm) hypothetical protein 0.003 0.0112 0.0374
Trichomonas vaginalis ran, putative 0.0021 0.0013 0.3182
Echinococcus granulosus GPCR family 2 0.0047 0.0283 0.0408
Schistosoma mansoni ran 0.0021 0.0013 0.0015
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0065 0.0473 0.0684
Schistosoma mansoni hypothetical protein 0.0047 0.0283 0.0408
Brugia malayi Calcitonin receptor-like protein seb-1 0.0148 0.1336 1
Echinococcus granulosus tumor protein p63 0.0408 0.4047 0.5885
Echinococcus granulosus snurportin 1 0.0303 0.2949 0.4287
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0002 0.0017
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0073 0.0559 0.081
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0047 0.0283 0.0408
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0379 0.3748 0.3746
Brugia malayi Latrophilin receptor protein 2 0.0047 0.0283 0.2116
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0047 0.0283 0.028
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0091 0.1878
Schistosoma mansoni aldehyde dehydrogenase 0.0073 0.0559 0.081
Onchocerca volvulus 0.006 0.0418 0.5
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0013 0.0095
Leishmania major hypothetical protein, conserved 0.003 0.0112 0.1977
Schistosoma mansoni hypothetical protein 0.0521 0.5219 0.7591
Plasmodium vivax ataxin-2 like protein, putative 0.003 0.0112 0.1827
Toxoplasma gondii kinesin motor domain-containing protein 0.0078 0.0605 1
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0013 0.0171
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0065 0.0473 0.78
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0002 0.5
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0047 0.0283 0.028
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0065 0.0473 0.0684
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0035 1
Echinococcus multilocularis snurportin 1 0.0303 0.2949 0.2947
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0065 0.0473 0.8441
Echinococcus granulosus neuropeptide receptor A26 0.0464 0.4634 0.6739
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0035 0.069
Schistosoma mansoni hypothetical protein 0.0101 0.0848 0.1231
Toxoplasma gondii HEAT repeat-containing protein 0.0028 0.0091 0.1465
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0473 1
Brugia malayi RNA, U transporter 1 0.0081 0.0635 0.4756
Echinococcus multilocularis neuropeptide receptor A26 0.0464 0.4634 0.4633
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0303 0.2949 1
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0013 0.0015
Trypanosoma cruzi PAB1-binding protein , putative 0.003 0.0112 0.2342
Schistosoma mansoni importin beta-1 0.0028 0.0091 0.0129
Schistosoma mansoni hypothetical protein 0.0303 0.2949 0.4287
Echinococcus multilocularis GPCR, family 2 0.0047 0.0283 0.028
Loa Loa (eye worm) hypothetical protein 0.0028 0.0091 0.03
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0073 0.0559 1
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0112 0.1827
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0065 0.0473 0.1596
Schistosoma mansoni cellular tumor antigen P53 0.006 0.0418 0.0604
Schistosoma mansoni hypothetical protein 0.0047 0.0283 0.0408
Trypanosoma brucei importin beta-1 subunit, putative 0.0028 0.0091 0.1878
Schistosoma mansoni kinesin eg-5 0.0078 0.0605 0.0877
Plasmodium falciparum importin beta, putative 0.0028 0.0091 0.1465
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0148 0.1336 1
Giardia lamblia Kinesin-5 0.0078 0.0605 1
Echinococcus granulosus microtubule associated protein 2 0.0679 0.6875 1
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0013 0.022
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0559 1
Plasmodium falciparum ataxin-2 like protein, putative 0.003 0.0112 0.1827
Echinococcus granulosus importin subunit beta 1 0.0028 0.0091 0.0129
Mycobacterium ulcerans aldehyde dehydrogenase 0.0073 0.0559 1
Echinococcus multilocularis kinesin family 1 0.0598 0.6029 0.6028
Loa Loa (eye worm) kinesin-like protein KLP2 0.0078 0.0605 0.2046
Echinococcus multilocularis importin subunit beta 1 0.0028 0.0091 0.0088
Toxoplasma gondii aldehyde dehydrogenase 0.0073 0.0559 0.9241
Loa Loa (eye worm) hypothetical protein 0.0047 0.0283 0.0951
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0035 1
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0002 0.5
Echinococcus multilocularis neuropeptide s receptor 0.0464 0.4634 0.4633
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0013 0.022
Schistosoma mansoni biogenic amine (5HT) receptor 0.0379 0.3748 0.545
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0013 0.0171
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0065 0.0473 0.3538
Schistosoma mansoni ran 0.0021 0.0013 0.0015
Schistosoma mansoni amine GPCR 0.0355 0.3498 0.5085
Brugia malayi Kinesin motor domain containing protein 0.0078 0.0605 0.453
Schistosoma mansoni microtubule-associated protein tau 0.0679 0.6875 1
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0065 0.0473 1
Echinococcus granulosus neuropeptide s receptor 0.0464 0.4634 0.6739
Loa Loa (eye worm) latrophilin receptor protein 2 0.0047 0.0283 0.0951
Echinococcus granulosus kinesin family 1 0.0598 0.6029 0.8769
Schistosoma mansoni hypothetical protein 0.0047 0.0283 0.0408
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0013 0.022

Activities

Activity type Activity value Assay description Source Reference
IC50 (functional) = 20.4 uM PUBCHEM_BIOASSAY: Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1). (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493160, AID493190] ChEMBL. No reference
IC50 (functional) = 23.8 uM PUBCHEM_BIOASSAY: Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493160, AID493190] ChEMBL. No reference
Potency (functional) = 0.631 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1). (Class of assay: confirmatory) [Related pubchem assays: 1030 (qHTS Validation Assay for Inhibitors of aldehyde dehydrogenase 1 (ALDH1A1))] ChEMBL. No reference
Potency (functional) 0.7943 uM PubChem BioAssay. Inhibitors of USP1/UAF1: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 5.0119 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Influenza NS1 Protein Function. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 5.2213 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) 8.2753 uM PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 48 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488752, AID488774, AID504848, AID504850] ChEMBL. No reference
Potency (functional) = 12.5893 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Permissive Temperature. (Class of assay: confirmatory) [Related pubchem assays: 902 ] ChEMBL. No reference
Potency (functional) 12.5893 uM PubChem BioAssay. qHTS for Inhibitors of ATXN expression. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 18.3564 uM PUBCHEM_BIOASSAY: qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID493107, AID493125] ChEMBL. No reference
Potency (functional) = 25.1189 um PUBCHEM_BIOASSAY: qHTS Screen for Compounds that Selectively Target Cancer Cells with p53 Mutations: Cytotoxicity of p53ts Cells at the Nonpermissive Temperature. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 25.1189 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID1473, AID2293, AID2577, AID2578, AID2587, AID2588, AID2589, AID2590, AID2592, AID2593, AID2595, AID2596, AID2597, AID2613, AID2671, AID488845] ChEMBL. No reference
Potency (functional) 28.1838 uM PubChem BioAssay. qHTS for Antagonists of gsp, the Etiologic Mutation Responsible for Fibrous Dysplasia/McCune-Albright Syndrome: qHTS. (Class of assay: confirmatory) ChEMBL. No reference
Potency (binding) = 31.6228 um PUBCHEM_BIOASSAY: qHTS for Inhibitors of Tau Fibril Formation, Thioflavin T Binding. (Class of assay: confirmatory) [Related pubchem assays: 596 ] ChEMBL. No reference
Potency (functional) = 31.6228 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase). (Class of assay: confirmatory) [Related pubchem assays: 2429 (Confirmation qHTS Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2407 (Probe Development Summary for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase)), 2427 (Thermal Shift Assay for Inhibitors of HPGD (15-Hydroxyprostaglandin Dehydrogenase))] ChEMBL. No reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor. (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (without detergent). (Class of assay: confirmatory) [Related pubchem assays: 2158 (Confirmation qHTS Assay for Inhibitors of Cruzain), 2249 (Probe Development Summary of Promiscuous Inhibitors (Artifacts) of Cruzain), 2161 (qHTS Assay for Inhibitors of Papain: Counterscreen for Cruzain Assay), 1478 (qHTS Assay for Promiscuous and Specific Inhibitors of Cruzain (with detergent))] ChEMBL. No reference
Potency (functional) = 39.8107 um PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of HADH2 (Hydroxyacyl-Coenzyme A Dehydrogenase, Type II). (Class of assay: confirmatory) ChEMBL. No reference
Potency (functional) 70.7946 uM PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Iota. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588623] ChEMBL. No reference
Potency (functional) 89.1251 uM PUBCHEM_BIOASSAY: HTS for Inhibitors of HP1-beta Chromodomain Interactions with Methylated Histone Tails. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488962] ChEMBL. No reference
Potency (functional) 112.2018 uM PubChem BioAssay. qHTS of PTHR Inhibitors: Primary Screen. (Class of assay: confirmatory) ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Plasmodium falciparum ChEMBL23

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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