Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | alkaline phosphatase | 0.0558 | 1 | 1 |
Schistosoma mansoni | alkaline phosphatase | 0.0558 | 1 | 1 |
Echinococcus multilocularis | alkaline phosphatase | 0.0558 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.029 | 0.4563 | 0.3308 |
Schistosoma mansoni | 23-cyclic-nucleotide 2-phosphodiesterase | 0.0158 | 0.1884 | 0.0011 |
Echinococcus granulosus | intestinal type alkaline phosphatase 1 | 0.0558 | 1 | 0.5 |
Echinococcus multilocularis | alkaline phosphatase, intestinal, gene 2 | 0.0558 | 1 | 0.5 |
Treponema pallidum | 5'-nucleotidase (ushA) | 0.0158 | 0.1884 | 0.5 |
Toxoplasma gondii | 5'-nucleotidase, C-terminal domain-containing protein | 0.0158 | 0.1884 | 1 |
Echinococcus multilocularis | intestinal type alkaline phosphatase 1 | 0.0558 | 1 | 0.5 |
Echinococcus multilocularis | intestinal type alkaline phosphatase | 0.0558 | 1 | 0.5 |
Echinococcus granulosus | alkaline phosphatase intestinal gene 2 | 0.0558 | 1 | 0.5 |
Echinococcus granulosus | alkaline phosphatase | 0.0558 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.