Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.019 | 0.7174 | 0.8836 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.019 | 0.7174 | 0.7174 |
Echinococcus granulosus | geminin | 0.0205 | 0.7948 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.01 | 0.2503 | 0.1812 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.009 | 0.1943 | 0.0969 |
Onchocerca volvulus | Bile acid receptor homolog | 0.019 | 0.7174 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.019 | 0.7174 | 0.7174 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.2503 | 0.2503 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.019 | 0.7174 | 0.7174 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.019 | 0.7174 | 0.8836 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.019 | 0.7174 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.009 | 0.1943 | 0.0969 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.019 | 0.7174 | 0.8836 |
Loa Loa (eye worm) | DR-78 | 0.009 | 0.1943 | 0.1943 |
Schistosoma mansoni | coup transcription factor | 0.019 | 0.7174 | 0.8836 |
Echinococcus multilocularis | acetylcholinesterase | 0.0078 | 0.1353 | 0.0083 |
Echinococcus granulosus | acetylcholinesterase | 0.0078 | 0.1353 | 0.0083 |
Brugia malayi | nuclear receptor NHR-67 | 0.009 | 0.1943 | 0.1943 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.7174 | 0.7174 |
Brugia malayi | steroid hormone receptor | 0.019 | 0.7174 | 0.7174 |
Brugia malayi | nuclear receptor RXR | 0.01 | 0.2503 | 0.2503 |
Brugia malayi | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.009 | 0.1943 | 0.0969 |
Loa Loa (eye worm) | carboxylesterase | 0.0078 | 0.1353 | 0.1353 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.2503 | 0.2503 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.009 | 0.1943 | 0.1943 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.019 | 0.7174 | 0.7174 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.019 | 0.7174 | 0.7174 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0078 | 0.1353 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.01 | 0.2503 | 0.1812 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.009 | 0.1943 | 0.0969 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.019 | 0.7174 | 0.7174 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.019 | 0.7174 | 0.8836 |
Brugia malayi | nuclear receptor RXR | 0.009 | 0.1943 | 0.1943 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.009 | 0.1943 | 0.0969 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.01 | 0.2503 | 0.2503 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.01 | 0.2503 | 0.1812 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.019 | 0.7174 | 0.7174 |
Echinococcus granulosus | acetylcholinesterase | 0.0078 | 0.1353 | 0.0083 |
Brugia malayi | TAR-binding protein | 0.0077 | 0.1298 | 0.1298 |
Brugia malayi | nuclear receptor NHR-88 | 0.019 | 0.7174 | 0.7174 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.7948 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.019 | 0.7174 | 0.8836 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.019 | 0.7174 | 0.8836 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.019 | 0.7174 | 0.7174 |
Brugia malayi | hypothetical protein | 0.01 | 0.2503 | 0.2503 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.2503 | 0.2503 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.019 | 0.7174 | 0.8836 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.019 | 0.7174 | 0.8836 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.019 | 0.7174 | 0.7174 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.019 | 0.7174 | 0.7174 |
Echinococcus granulosus | carboxylesterase 5A | 0.0078 | 0.1353 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Schistosoma mansoni | nuclear receptor | 0.009 | 0.1943 | 0.0969 |
Brugia malayi | ecdysteroid receptor | 0.019 | 0.7174 | 0.7174 |
Brugia malayi | Carboxylesterase family protein | 0.0078 | 0.1353 | 0.1353 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.019 | 0.7174 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.7174 | 0.7174 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.019 | 0.7174 | 0.8836 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.019 | 0.7174 | 0.8836 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.019 | 0.7174 | 0.8836 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.019 | 0.7174 | 0.8836 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.019 | 0.7174 | 0.7174 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.019 | 0.7174 | 0.7174 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.019 | 0.7174 | 0.8836 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.009 | 0.1943 | 0.1943 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0078 | 0.1353 | 0.0083 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.7174 | 0.7174 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.2503 | 0.2503 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.009 | 0.1943 | 0.1943 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.009 | 0.1943 | 0.0969 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.7174 | 0.7174 |
Schistosoma mansoni | nuclear hormone receptor | 0.009 | 0.1943 | 0.0969 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.009 | 0.1943 | 0.0969 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.7174 | 0.7174 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.019 | 0.7174 | 0.7174 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.2503 | 0.2503 |
Onchocerca volvulus | 0.019 | 0.7174 | 1 | |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.019 | 0.7174 | 0.7174 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.019 | 0.7174 | 0.7174 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.009 | 0.1943 | 0.0969 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.009 | 0.1943 | 0.0969 |
Brugia malayi | ecdysone receptor | 0.009 | 0.1943 | 0.1943 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.009 | 0.1943 | 0.0969 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0078 | 0.1353 | 0.1353 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.019 | 0.7174 | 0.8836 |
Schistosoma mansoni | nuclear hormone receptor | 0.009 | 0.1943 | 0.0969 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.009 | 0.1943 | 0.1943 |
Schistosoma mansoni | zinc finger protein | 0.009 | 0.1943 | 0.0969 |
Loa Loa (eye worm) | RNA binding protein | 0.0077 | 0.1298 | 0.1298 |
Loa Loa (eye worm) | steroid hormone receptor | 0.019 | 0.7174 | 0.7174 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.019 | 0.7174 | 0.7174 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.019 | 0.7174 | 0.8836 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.019 | 0.7174 | 0.8836 |
Brugia malayi | nuclear receptor NHR-88 | 0.009 | 0.1943 | 0.1943 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0244 | 1 | 1 |
Schistosoma mansoni | nuclear receptor | 0.009 | 0.1943 | 0.0969 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.009 | 0.1943 | 0.0969 |
Brugia malayi | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.019 | 0.7174 | 0.8836 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.009 | 0.1943 | 0.1943 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.009 | 0.1943 | 0.0969 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.01 | 0.2503 | 0.2503 |
Schistosoma mansoni | thyroid hormone receptor | 0.019 | 0.7174 | 0.8836 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.019 | 0.7174 | 0.7174 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.019 | 0.7174 | 0.8836 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.019 | 0.7174 | 0.8836 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1353 | 0.1353 |
Schistosoma mansoni | nuclear hormone receptor | 0.019 | 0.7174 | 0.8836 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0077 | 0.1298 | 0.1298 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.009 | 0.1943 | 0.0969 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.019 | 0.7174 | 0.8836 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.7174 | 0.7174 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.019 | 0.7174 | 0.8836 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.019 | 0.7174 | 0.8836 |
Brugia malayi | RNA binding protein | 0.0077 | 0.1298 | 0.1298 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.019 | 0.7174 | 0.7174 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.019 | 0.7174 | 0.7174 |
Echinococcus multilocularis | acetylcholinesterase | 0.0078 | 0.1353 | 0.0083 |
Loa Loa (eye worm) | TAR-binding protein | 0.0077 | 0.1298 | 0.1298 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Brugia malayi | Nuclear hormone receptor E75 | 0.009 | 0.1943 | 0.1943 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.009 | 0.1943 | 0.0969 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.019 | 0.7174 | 0.7174 |
Brugia malayi | Nuclear hormone receptor E75 | 0.009 | 0.1943 | 0.1943 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.009 | 0.1943 | 0.1943 |
Brugia malayi | nuclear hormone receptor | 0.009 | 0.1943 | 0.1943 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.1353 | 0.1353 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.009 | 0.1943 | 0.1943 |
Echinococcus multilocularis | FTZ F1 alpha | 0.019 | 0.7174 | 0.8836 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.01 | 0.2503 | 0.2503 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.019 | 0.7174 | 0.7174 |
Brugia malayi | hypothetical protein | 0.01 | 0.2503 | 0.2503 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.01 | 0.2503 | 0.1812 |
Echinococcus multilocularis | geminin | 0.0205 | 0.7948 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.019 | 0.7174 | 0.8836 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.7174 | 0.7174 |
Brugia malayi | conserved hypotetical protein | 0.009 | 0.1943 | 0.1943 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.019 | 0.7174 | 0.8836 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0077 | 0.1298 | 0.1298 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.019 | 0.7174 | 0.7174 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.019 | 0.7174 | 0.8836 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.019 | 0.7174 | 0.7174 |
Brugia malayi | Carboxylesterase family protein | 0.0078 | 0.1353 | 0.1353 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.019 | 0.7174 | 0.8836 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.7948 | 1 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.009 | 0.1943 | 0.0969 |
Brugia malayi | tailless protein | 0.009 | 0.1943 | 0.1943 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.1943 | 0.1943 |
Brugia malayi | nuclear hormone receptor | 0.019 | 0.7174 | 0.7174 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.019 | 0.7174 | 0.8836 |
Loa Loa (eye worm) | hypothetical protein | 0.019 | 0.7174 | 0.7174 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.