Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | serine:threonine protein phosphatase 2B | 0.0082 | 0 | 0.5 |
Echinococcus multilocularis | serine:threonine protein phosphatase 2B | 0.0082 | 0 | 0.5 |
Plasmodium vivax | chloroquine resistance transporter, putative | 0.0264 | 1 | 1 |
Entamoeba histolytica | calcineurin catalytic subunit A, putative | 0.0082 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0098 | 0.0881 | 0.5 |
Schistosoma mansoni | protein phosphatase-2b | 0.0082 | 0 | 0.5 |
Trypanosoma brucei | protein phosphatase 2B, putative | 0.0082 | 0 | 0.5 |
Toxoplasma gondii | transmembrane protein | 0.0264 | 1 | 1 |
Brugia malayi | Serine/threonine protein phosphatase 2B catalytic subunit 2 | 0.0082 | 0 | 0.5 |
Entamoeba histolytica | calcineurin catalytic subunit A, putative | 0.0082 | 0 | 0.5 |
Plasmodium falciparum | conserved Plasmodium membrane protein, unknown function | 0.0098 | 0.0881 | 0.0881 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0098 | 0.0881 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0098 | 0.0881 | 0.0881 |
Entamoeba histolytica | calcineurin catalytic subunit A, putative | 0.0082 | 0 | 0.5 |
Leishmania major | serine/threonine protein phosphatase, putative | 0.0082 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 0 | 0.5 |
Schistosoma mansoni | protein phosphatase-2b | 0.0082 | 0 | 0.5 |
Leishmania major | serine/threonine protein phosphatase 2B catalytic subunit A2, putative | 0.0082 | 0 | 0.5 |
Entamoeba histolytica | Ser/Thr protein phosphatase, putative | 0.0082 | 0 | 0.5 |
Entamoeba histolytica | Ser/Thr protein phosphatase, putative | 0.0082 | 0 | 0.5 |
Echinococcus multilocularis | serine:threonine protein phosphatase 2B | 0.0082 | 0 | 0.5 |
Echinococcus granulosus | serine:threonine protein phosphatase 2B | 0.0082 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0098 | 0.0881 | 1 |
Entamoeba histolytica | calcineurin catalytic subunit A, putative | 0.0082 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.