Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0091 | 0.0977 | 0.5 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0337 | 0.5017 | 0.5017 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0631 | 0.9866 | 1 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0091 | 0.0977 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0091 | 0.0977 | 0.5 |
Echinococcus granulosus | acylamino acid releasing enzyme | 0.0091 | 0.0977 | 0.0977 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0091 | 0.0977 | 0.5 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0631 | 0.9866 | 0.9866 |
Brugia malayi | Muscleblind-like protein | 0.0163 | 0.2168 | 0.2168 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0091 | 0.0977 | 0.0977 |
Mycobacterium tuberculosis | Probable peptidase | 0.0091 | 0.0977 | 0.5 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0639 | 1 | 1 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0631 | 0.9866 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.2168 | 0.2168 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0091 | 0.0977 | 0.5 |
Echinococcus multilocularis | acylamino acid releasing enzyme | 0.0091 | 0.0977 | 0.0977 |
Echinococcus granulosus | prolyl endopeptidase | 0.0091 | 0.0977 | 0.0977 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0639 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0977 | 0.0977 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0091 | 0.0977 | 0.5 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0091 | 0.0977 | 0.5 |
Echinococcus granulosus | snurportin 1 | 0.0337 | 0.5017 | 0.5017 |
Trypanosoma brucei | prolyl oligopeptidase, putative | 0.0091 | 0.0977 | 0.099 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0091 | 0.0977 | 0.0977 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0163 | 0.2168 | 0.2168 |
Plasmodium falciparum | peptidase, putative | 0.0091 | 0.0977 | 1 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0639 | 1 | 1 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0631 | 0.9866 | 1 |
Trypanosoma brucei | serine peptidase, clan SC, family S9A-like protein | 0.0091 | 0.0977 | 0.099 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0091 | 0.0977 | 0.0977 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0639 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0295 | 0.433 | 0.433 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0977 | 0.0977 |
Toxoplasma gondii | acylaminoacyl-peptidase, putative | 0.0091 | 0.0977 | 0.1677 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0631 | 0.9866 | 0.9866 |
Trypanosoma brucei | oligopeptidase b | 0.0091 | 0.0977 | 0.099 |
Plasmodium vivax | hypothetical protein, conserved | 0.0091 | 0.0977 | 1 |
Schistosoma mansoni | acylaminoacyl-peptidase (S09 family) | 0.0091 | 0.0977 | 0.0977 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0631 | 0.9866 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0091 | 0.0977 | 0.5 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0091 | 0.0977 | 0.5 |
Trypanosoma brucei | prolyl endopeptidase | 0.0091 | 0.0977 | 0.099 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0091 | 0.0977 | 0.0977 |
Mycobacterium tuberculosis | Probable protease II PtrBb [second part] (oligopeptidase B) | 0.0091 | 0.0977 | 0.5 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0091 | 0.0977 | 0.0977 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0631 | 0.9866 | 1 |
Echinococcus multilocularis | snurportin 1 | 0.0337 | 0.5017 | 0.5017 |
Echinococcus granulosus | muscleblind protein | 0.0163 | 0.2168 | 0.2168 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0639 | 1 | 1 |
Echinococcus multilocularis | muscleblind protein | 0.0163 | 0.2168 | 0.2168 |
Toxoplasma gondii | hypothetical protein | 0.0091 | 0.0977 | 0.1677 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0091 | 0.0977 | 0.0977 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0091 | 0.0977 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0631 | 0.9866 | 0.9866 |
Trypanosoma brucei | Alpha/beta hydrolase domain-containing protein | 0.0091 | 0.0977 | 0.099 |
Schistosoma mansoni | hypothetical protein | 0.0337 | 0.5017 | 0.5017 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0091 | 0.0977 | 0.0977 |
Toxoplasma gondii | prolyl endopeptidase | 0.0091 | 0.0977 | 0.1677 |
Loa Loa (eye worm) | hypothetical protein | 0.0337 | 0.5018 | 0.5018 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0091 | 0.0977 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.2168 | 0.2168 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0091 | 0.0977 | 0.5 |
Brugia malayi | hypothetical protein | 0.0295 | 0.433 | 0.433 |
Brugia malayi | RNA, U transporter 1 | 0.009 | 0.0956 | 0.0956 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0091 | 0.0977 | 0.0977 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0631 | 0.9866 | 0.9866 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0386 | 0.5825 | 1 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0091 | 0.0977 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.