Detailed information for compound 1478762

Basic information

Technical information
  • TDR Targets ID: 1478762
  • Name: 2-(1,3-benzodioxol-5-yl)-3-(3-diethylaminopro pyl)-1,3-thiazolidin-4-one
  • MW: 336.449 | Formula: C17H24N2O3S
  • H donors: 0 H acceptors: 1 LogP: 2.74 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCN(CCCN1C(=O)CSC1c1ccc2c(c1)OCO2)CC
  • InChi: 1S/C17H24N2O3S/c1-3-18(4-2)8-5-9-19-16(20)11-23-17(19)13-6-7-14-15(10-13)22-12-21-14/h6-7,10,17H,3-5,8-9,11-12H2,1-2H3
  • InChiKey: QTXWWNASIXBEBM-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • 2-(1,3-benzodioxol-5-yl)-3-(3-diethylaminopropyl)thiazolidin-4-one
  • 2-(1,3-benzodioxol-5-yl)-3-(3-diethylaminopropyl)-4-thiazolidinone
  • Oprea1_166581

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Schistosoma mansoni neuropeptide receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Schistosoma mansoni neuropeptide receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0656 0.0619
Brugia malayi hypothetical protein 0.0024 0.0656 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Brugia malayi GnHR receptor homolog 0.0024 0.0656 1
Trichomonas vaginalis hypothetical protein 0.0018 0.0039 0.5
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Toxoplasma gondii PA14 domain-containing protein 0.0018 0.0039 0.5
Schistosoma mansoni opsin-like receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0656 0.0619
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0656 0.0619
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Plasmodium vivax LCCL domain-containing protein 0.0018 0.0039 0.5
Echinococcus granulosus g-protein coupled receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis neuropeptide s receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Schistosoma mansoni neuropeptide receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis dedicator of cytokinesis protein 0.0096 0.8127 0.812
Brugia malayi larval opioid receptor 0.0024 0.0656 1
Schistosoma mansoni amine GPCR 0.0024 0.0656 0.0619
Toxoplasma gondii F5/8 type C domain-containing protein 0.0018 0.0039 0.5
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0656 0.0619
Schistosoma mansoni myosin xvIII 0.0024 0.0656 0.0619
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0656 0.0619
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Schistosoma mansoni neuropeptide receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0024 0.0656 1
Toxoplasma gondii F5/8 type C domain-containing protein 0.0018 0.0039 0.5
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Schistosoma mansoni amine GPCR 0.0024 0.0656 0.0619
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0656 0.0619
Schistosoma mansoni opsin-like receptor 0.0024 0.0656 0.0619
Schistosoma mansoni dock 0.0113 1 1
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0656 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis g protein coupled receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0024 0.0656 1
Echinococcus multilocularis G protein coupled receptor 139 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0024 0.0656 0.0619
Echinococcus granulosus g protein coupled receptor 0.0024 0.0656 0.0619
Brugia malayi Dopamine receptor protein 1 0.0024 0.0656 1
Toxoplasma gondii F5/8 type C domain-containing protein 0.0018 0.0039 0.5
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0024 0.0656 1
Trichomonas vaginalis beta-hexosaminidase B, putative 0.0018 0.0039 0.5
Schistosoma mansoni opsin-like receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0024 0.0656 1
Onchocerca volvulus 0.0024 0.0656 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0024 0.0656 1
Echinococcus multilocularis g-protein coupled receptor 0.0024 0.0656 0.0619
Echinococcus granulosus neuropeptide FF receptor 2 0.0024 0.0656 0.0619
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0024 0.0656 0.0619
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0656 0.0619
Brugia malayi neuropeptide F receptor 0.0024 0.0656 1
Plasmodium falciparum LCCL domain-containing protein 0.0018 0.0039 0.5
Brugia malayi Tachykinin-like peptides receptor 99D 0.0024 0.0656 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0024 0.0656 1
Onchocerca volvulus 0.0024 0.0656 1
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0656 0.0619
Brugia malayi G protein-coupled receptor F59B2.13 0.0024 0.0656 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0656 0.0619
Brugia malayi ORL1-like opioid receptor 0.0024 0.0656 1
Brugia malayi hypothetical protein 0.0024 0.0656 1
Onchocerca volvulus 0.0024 0.0656 1
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0656 1
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Echinococcus granulosus somatostatin receptor 0.0024 0.0656 0.0619
Echinococcus granulosus peptide allatostatin:somatostatin 0.0024 0.0656 0.0619
Schistosoma mansoni histamine h1 receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0024 0.0656 0.0619
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0656 0.0619
Brugia malayi Dopamine receptor protein 2 0.0024 0.0656 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0024 0.0656 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Brugia malayi G-protein coupled receptor 0.0024 0.0656 1
Brugia malayi hypothetical protein 0.0024 0.0656 1
Mycobacterium leprae PROBABLE CONSERVED TRANSMEMBRANE PROTEIN 0.0018 0.0039 0.5
Loa Loa (eye worm) TYRA-2 protein 0.0024 0.0656 1
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0656 1
Schistosoma mansoni hypothetical protein 0.0024 0.0656 0.0619
Schistosoma mansoni neuropeptide f receptor 76f 0.0024 0.0656 0.0619
Schistosoma mansoni growth hormone secretagogue receptor 0.0024 0.0656 0.0619
Brugia malayi AKH receptor 0.0024 0.0656 1
Schistosoma mansoni biogenic amine receptor 0.0024 0.0656 0.0619
Schistosoma mansoni amine GPCR 0.0024 0.0656 0.0619
Echinococcus granulosus allatostatin A receptor 0.0024 0.0656 0.0619
Mycobacterium ulcerans oxidase 0.0018 0 0.5
Onchocerca volvulus 0.0024 0.0656 1
Onchocerca volvulus 0.0024 0.0656 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Echinococcus granulosus tachykinin peptides receptor 99D 0.0024 0.0656 0.0619
Schistosoma mansoni hypothetical protein 0.0024 0.0656 0.0619
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0024 0.0656 0.0619
Onchocerca volvulus 0.0024 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Echinococcus granulosus orexin receptor type 2 0.0024 0.0656 0.0619
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0024 0.0656 0.0619
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0024 0.0656 1
Echinococcus granulosus G protein coupled receptor 139 0.0024 0.0656 0.0619
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0024 0.0656 1
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0656 0.0619
Brugia malayi hypothetical protein 0.0024 0.0656 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0024 0.0656 0.0619
Schistosoma mansoni adenoreceptor 0.0024 0.0656 0.0619
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0656 0.0619
Echinococcus granulosus dro:myosuppressin receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0656 0.0619
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0656 0.0619
Echinococcus multilocularis dro:myosuppressin receptor 0.0024 0.0656 0.0619
Onchocerca volvulus 0.0024 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Echinococcus multilocularis neuropeptides capa receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis neuropeptide receptor A26 0.0024 0.0656 0.0619
Schistosoma mansoni hypothetical protein 0.0024 0.0656 0.0619
Onchocerca volvulus 0.0024 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0656 0.0619
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0656 0.0619
Brugia malayi sulfakinin receptor protein 0.0024 0.0656 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0024 0.0656 0.0619
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0024 0.0656 0.0619
Brugia malayi Serotonin receptor 0.0024 0.0656 1
Echinococcus multilocularis serotonin receptor 0.0024 0.0656 0.0619
Schistosoma mansoni biogenic amine receptor 0.0024 0.0656 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Echinococcus multilocularis neuropeptide FF receptor 2 0.0024 0.0656 0.0619
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0656 0.0619
Echinococcus granulosus tm gpcr rhodopsin 0.0024 0.0656 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0024 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0656 0.0619
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Onchocerca volvulus 0.0024 0.0656 1
Echinococcus granulosus g protein coupled receptor 0.0024 0.0656 0.0619
Onchocerca volvulus 0.0024 0.0656 1
Echinococcus multilocularis neuropeptide receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Brugia malayi G-protein coupled receptor 0.0024 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis orexin receptor type 2 0.0024 0.0656 0.0619
Loa Loa (eye worm) neuropeptide F receptor 0.0024 0.0656 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0024 0.0656 1
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Brugia malayi hypothetical protein 0.0024 0.0656 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0024 0.0656 1
Plasmodium falciparum LCCL domain-containing protein 0.0018 0.0039 0.5
Echinococcus multilocularis G-protein coupled receptor, putative 0.0024 0.0656 0.0619
Echinococcus granulosus fmrfamide receptor 0.0024 0.0656 0.0619
Schistosoma mansoni biogenic amine receptor 0.0024 0.0656 0.0619
Echinococcus granulosus neuropeptide s receptor 0.0024 0.0656 0.0619
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0024 0.0656 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Echinococcus granulosus 7TM GPCR rhodopsin 0.0024 0.0656 0.0619
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Echinococcus granulosus sex peptide receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Echinococcus multilocularis allatostatin A receptor 0.0024 0.0656 0.0619
Echinococcus granulosus neuropeptide Y receptor 0.0024 0.0656 0.0619
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Brugia malayi RE15519p 0.0024 0.0656 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0024 0.0656 0.0619
Echinococcus multilocularis fmrfamide receptor 0.0024 0.0656 0.0619
Onchocerca volvulus 0.0024 0.0656 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0024 0.0656 0.0619
Onchocerca volvulus 0.0024 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Mycobacterium tuberculosis Possible arabinofuranosyltransferase AftD 0.0018 0.0039 1
Brugia malayi hypothetical protein 0.0024 0.0656 1
Schistosoma mansoni hypothetical protein 0.0024 0.0656 0.0619
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Echinococcus granulosus 7tm_1 domain containing protein 0.0024 0.0656 0.0619
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0024 0.0656 0.0619
Brugia malayi hypothetical protein 0.0024 0.0656 1
Echinococcus granulosus g protein coupled receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0656 0.0619
Loa Loa (eye worm) G-protein coupled receptor 0.0024 0.0656 1
Echinococcus multilocularis neuropeptide Y receptor 0.0024 0.0656 0.0619
Echinococcus granulosus rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Onchocerca volvulus 0.0024 0.0656 1
Brugia malayi hypothetical protein 0.0024 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Onchocerca volvulus 0.0024 0.0656 1
Brugia malayi Melatonin receptor type 1A 0.0024 0.0656 1
Echinococcus granulosus neuropeptide receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0018 0.0039 0.5
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0024 0.0656 0.0619
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis serotonin receptor 0.0024 0.0656 0.0619
Echinococcus granulosus neuropeptide receptor 0.0024 0.0656 0.0619
Brugia malayi putative neuropeptide receptor 0.0024 0.0656 1
Onchocerca volvulus 0.0024 0.0656 1
Brugia malayi neuropeptide F receptor 0.0024 0.0656 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0656 0.0619
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0024 0.0656 0.0619
Echinococcus granulosus neuropeptide receptor A26 0.0024 0.0656 0.0619
Schistosoma mansoni neuropeptide F-like receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Onchocerca volvulus 0.0024 0.0656 1
Schistosoma mansoni amine GPCR 0.0024 0.0656 0.0619
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0024 0.0656 1
Brugia malayi hypothetical protein 0.0024 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0024 0.0656 0.0619
Schistosoma mansoni amine GPCR 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Onchocerca volvulus 0.0024 0.0656 1
Brugia malayi putative neuropeptide receptor NPR1 0.0024 0.0656 1
Echinococcus granulosus neuropeptides capa receptor 0.0024 0.0656 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0656 0.0619
Brugia malayi follicle stimulating hormone receptor 0.0024 0.0656 1
Echinococcus granulosus hypothetical protein 0.0024 0.0656 0.0619
Schistosoma mansoni alpha-1 adrenergic receptor 0.0024 0.0656 0.0619
Plasmodium vivax LCCL domain-containing protein 0.0018 0.0039 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Echinococcus multilocularis Coagulation factor 5 8 type, C terminal 0.0113 1 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis sex peptide receptor 0.0024 0.0656 0.0619
Brugia malayi Dopamine receptor 0.0024 0.0656 1
Brugia malayi G protein-coupled receptor 0.0024 0.0656 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0024 0.0656 1
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0024 0.0656 0.0619
Trichomonas vaginalis alpha-L-fucosidase, putative 0.0018 0.0039 0.5
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0024 0.0656 0.0619
Loa Loa (eye worm) hypothetical protein 0.0024 0.0656 1
Brugia malayi hypothetical protein 0.0024 0.0656 1
Echinococcus granulosus serotonin receptor 0.0024 0.0656 0.0619
Echinococcus multilocularis somatostatin receptor 0.0024 0.0656 0.0619
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0024 0.0656 0.0619
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0039 0.5
Brugia malayi Serotonin receptor 0.0024 0.0656 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0024 0.0656 0.0619

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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