Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | cathepsin L-like protease | 0.063 | 0.358 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.063 | 0.358 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.063 | 0.358 | 0.358 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.063 | 0.358 | 0.2754 |
Giardia lamblia | Cathepsin B precursor | 0.0454 | 0.1407 | 0.5 |
Brugia malayi | Papain family cysteine protease containing protein | 0.063 | 0.358 | 0.358 |
Loa Loa (eye worm) | fibroinase | 0.063 | 0.358 | 0.2754 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.063 | 0.358 | 0.358 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.063 | 0.358 | 0.358 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.063 | 0.358 | 1 |
Onchocerca volvulus | 0.063 | 0.358 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.063 | 0.358 | 0.358 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.063 | 0.358 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.063 | 0.358 | 0.2754 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.063 | 0.358 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.063 | 0.358 | 0.358 |
Brugia malayi | cathepsin L-like precursor | 0.0432 | 0.1139 | 0.1139 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.063 | 0.358 | 1 |
Echinococcus multilocularis | cysteine protease | 0.063 | 0.358 | 0.358 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.063 | 0.358 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0432 | 0.1139 | 0.3182 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.063 | 0.358 | 0.358 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.063 | 0.358 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.063 | 0.358 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0454 | 0.1407 | 0.1407 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.063 | 0.358 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0432 | 0.1139 | 0.3182 |
Loa Loa (eye worm) | hypothetical protein | 0.063 | 0.358 | 0.2754 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0432 | 0.1139 | 0.3182 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.063 | 0.358 | 0.358 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.063 | 0.358 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.063 | 0.358 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0432 | 0.1139 | 0.1139 |
Echinococcus multilocularis | cysteine protease | 0.063 | 0.358 | 0.358 |
Brugia malayi | Cathepsin L-like precursor | 0.063 | 0.358 | 0.358 |
Entamoeba histolytica | cysteine proteinase, putative | 0.063 | 0.358 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.063 | 0.358 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.063 | 0.358 | 0.358 |
Loa Loa (eye worm) | cathepsin B | 0.0454 | 0.1407 | 0.0302 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0432 | 0.1139 | 0.1139 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0454 | 0.1407 | 0.3931 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.063 | 0.358 | 1 |
Onchocerca volvulus | 0.063 | 0.358 | 1 | |
Leishmania major | cathepsin L-like protease | 0.063 | 0.358 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.063 | 0.358 | 0.2754 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.063 | 0.358 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.063 | 0.358 | 0.358 |
Leishmania major | cathepsin L-like protease | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.063 | 0.358 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.063 | 0.358 | 0.2754 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.063 | 0.358 | 0.358 |
Brugia malayi | Cathepsin L-like precursor | 0.063 | 0.358 | 0.358 |
Brugia malayi | Cathepsin L-like precursor | 0.0432 | 0.1139 | 0.1139 |
Plasmodium vivax | vivapain-2 | 0.063 | 0.358 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0454 | 0.1407 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.063 | 0.358 | 1 |
Onchocerca volvulus | 0.063 | 0.358 | 1 | |
Leishmania major | cathepsin L-like protease | 0.063 | 0.358 | 1 |
Onchocerca volvulus | Cathepsin F homolog | 0.063 | 0.358 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0454 | 0.1407 | 0.1407 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0454 | 0.1407 | 0.3931 |
Entamoeba histolytica | cysteine proteinase, putative | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.063 | 0.358 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0454 | 0.1407 | 0.5 |
Onchocerca volvulus | Cathepsin L homolog | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.063 | 0.358 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.063 | 0.358 | 0.358 |
Entamoeba histolytica | cysteine protease, putative | 0.063 | 0.358 | 1 |
Leishmania major | cathepsin L-like protease | 0.063 | 0.358 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0432 | 0.1139 | 0.1139 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.063 | 0.358 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.063 | 0.358 | 0.358 |
Onchocerca volvulus | 0.063 | 0.358 | 1 | |
Onchocerca volvulus | 0.063 | 0.358 | 1 | |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0432 | 0.1139 | 0.1139 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.063 | 0.358 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.063 | 0.358 | 0.358 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.063 | 0.358 | 1 |
Leishmania major | cathepsin L-like protease | 0.063 | 0.358 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.063 | 0.358 | 1 |
Onchocerca volvulus | 0.063 | 0.358 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.063 | 0.358 | 0.358 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.063 | 0.358 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.063 | 0.358 | 0.358 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.063 | 0.358 | 1 |
Leishmania major | cathepsin L-like protease | 0.063 | 0.358 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.063 | 0.358 | 0.358 |
Leishmania major | cysteine peptidase A (CPA) | 0.063 | 0.358 | 1 |
Toxoplasma gondii | cathepsin CPL | 0.063 | 0.358 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.063 | 0.358 | 0.358 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.063 | 0.358 | 1 |
Onchocerca volvulus | 0.063 | 0.358 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.063 | 0.358 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.063 | 0.358 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.063 | 0.358 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0432 | 0.1139 | 0.1139 |
Leishmania major | cathepsin L-like protease | 0.063 | 0.358 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.063 | 0.358 | 0.358 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.063 | 0.358 | 1 |
Plasmodium vivax | vivapain-2 | 0.063 | 0.358 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.