Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | v-akt murine thymoma viral oncogene homolog 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Protein kinase domain containing protein | 0.004 | 0.0316 | 0.0316 |
Giardia lamblia | Ribokinase | 0.01 | 0.1007 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0038 | 0.0287 | 0.2851 |
Echinococcus granulosus | Glutaredoxin protein 5 | 0.0025 | 0.0137 | 0.0137 |
Trichomonas vaginalis | AGC family protein kinase | 0.004 | 0.0316 | 0.3136 |
Echinococcus multilocularis | Glutaredoxin protein 5 | 0.0025 | 0.0137 | 0.0137 |
Brugia malayi | Ribokinase | 0.01 | 0.1007 | 0.1007 |
Trichomonas vaginalis | ribokinase, putative | 0.01 | 0.1007 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.004 | 0.0316 | 0.3136 |
Trypanosoma cruzi | adenosine kinase, putative | 0.01 | 0.1007 | 0.0879 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0038 | 0.0287 | 0.0287 |
Echinococcus multilocularis | sodium:potassium dependent atpase beta subunit | 0.0025 | 0.0137 | 0.0137 |
Entamoeba histolytica | ribokinase, putative | 0.01 | 0.1007 | 1 |
Mycobacterium tuberculosis | Adenosine kinase | 0.01 | 0.1007 | 0.5 |
Trichomonas vaginalis | ribokinase, putative | 0.01 | 0.1007 | 1 |
Echinococcus granulosus | serine threonine protein kinase nrc | 0.0025 | 0.0141 | 0.0141 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0028 | 0.0169 | 0.1682 |
Entamoeba histolytica | Hypothetical protein T24C12.3, putative | 0.01 | 0.1007 | 1 |
Echinococcus multilocularis | pseudouridine metabolizing bifunctional protein | 0.01 | 0.1007 | 0.1007 |
Echinococcus multilocularis | ribokinase | 0.01 | 0.1007 | 0.1007 |
Echinococcus granulosus | ribokinase | 0.01 | 0.1007 | 0.1007 |
Mycobacterium ulcerans | fructokinase, PfkB | 0.01 | 0.1007 | 0.5 |
Echinococcus multilocularis | rac serine:threonine kinase | 0.0028 | 0.0169 | 0.0169 |
Trypanosoma brucei | ribokinase, putative | 0.01 | 0.1007 | 0.0714 |
Entamoeba histolytica | fructokinase, putative | 0.01 | 0.1007 | 1 |
Trypanosoma cruzi | Protein kinase B | 0.0028 | 0.0169 | 0.0029 |
Trichomonas vaginalis | AGC family protein kinase | 0.004 | 0.0316 | 0.3136 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0028 | 0.0169 | 0.1682 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0028 | 0.0169 | 0.0169 |
Trypanosoma brucei | ribokinase, putative | 0.01 | 0.1007 | 0.0714 |
Entamoeba histolytica | protein kinase, putative | 0.004 | 0.0316 | 0.3136 |
Echinococcus granulosus | serine/threonine protein kinase | 0.0028 | 0.0169 | 0.0169 |
Brugia malayi | hypothetical protein | 0.01 | 0.1007 | 0.1007 |
Entamoeba histolytica | kinase, PfkB family | 0.01 | 0.1007 | 1 |
Mycobacterium ulcerans | carbohydrate kinase CbhK | 0.01 | 0.1007 | 0.5 |
Plasmodium falciparum | RAC-beta serine/threonine protein kinase | 0.0025 | 0.0141 | 0.5 |
Echinococcus granulosus | nervana 2 | 0.0025 | 0.0137 | 0.0137 |
Trypanosoma cruzi | ribokinase, putative | 0.01 | 0.1007 | 0.0879 |
Trypanosoma cruzi | rac serine-threonine kinase, putative | 0.0028 | 0.0169 | 0.0029 |
Trichomonas vaginalis | ribokinase, putative | 0.01 | 0.1007 | 1 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0038 | 0.0287 | 0.0287 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1007 | 0.1007 |
Echinococcus multilocularis | nervana 2 | 0.0025 | 0.0137 | 0.0137 |
Onchocerca volvulus | 0.0776 | 0.8843 | 1 | |
Trichomonas vaginalis | AGC family protein kinase | 0.004 | 0.0316 | 0.3136 |
Entamoeba histolytica | protein kinase, putative | 0.004 | 0.0316 | 0.3136 |
Plasmodium vivax | rac-beta serine/threonine protein kinase, putative | 0.0025 | 0.0141 | 0.5 |
Schistosoma mansoni | serine/threonine-protein kinase | 0.0028 | 0.0169 | 0.0169 |
Loa Loa (eye worm) | hypothetical protein | 0.01 | 0.1007 | 0.1007 |
Toxoplasma gondii | kinase, pfkB family protein | 0.01 | 0.1007 | 0.0741 |
Echinococcus granulosus | pseudouridine metabolizing bifunctional protein | 0.01 | 0.1007 | 0.1007 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.004 | 0.0316 | 0.0316 |
Entamoeba histolytica | tagatose-6-phosphate kinase, putative | 0.01 | 0.1007 | 1 |
Entamoeba histolytica | protein kinase 2, putative | 0.0025 | 0.0141 | 0.1397 |
Mycobacterium tuberculosis | Ribokinase RbsK | 0.01 | 0.1007 | 0.5 |
Echinococcus granulosus | calcium:calmodulin dependent protein kinase | 0.0025 | 0.0141 | 0.0141 |
Echinococcus granulosus | sodium:potassium dependent atpase beta subunit | 0.0025 | 0.0137 | 0.0137 |
Echinococcus multilocularis | serine threonine protein kinase nrc serine threonine protein kinase gad | 0.0025 | 0.0141 | 0.0141 |
Trichomonas vaginalis | AGC family protein kinase | 0.004 | 0.0316 | 0.3136 |
Trichomonas vaginalis | AGC family protein kinase | 0.0015 | 0.0029 | 0.0285 |
Trypanosoma cruzi | adenosine kinase, putative | 0.01 | 0.1007 | 0.0879 |
Mycobacterium leprae | Probable adenosine kinase adk | 0.01 | 0.1007 | 0.5 |
Schistosoma mansoni | ribokinase | 0.01 | 0.1007 | 0.1007 |
Trichomonas vaginalis | conserved hypothetical protein | 0.01 | 0.1007 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.004 | 0.0316 | 0.3136 |
Echinococcus granulosus | nervana 2 | 0.0025 | 0.0137 | 0.0137 |
Mycobacterium tuberculosis | 6-phosphofructokinase PfkB (phosphohexokinase) (phosphofructokinase) | 0.01 | 0.1007 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.004 | 0.0316 | 0.3136 |
Echinococcus multilocularis | nervana 2 | 0.0025 | 0.0137 | 0.0137 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.