Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | insulin-like growth factor 1 receptor | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0197 | 0.0879 | 0.5 | |
Plasmodium falciparum | protoporphyrinogen oxidase | 0.0197 | 0.0879 | 0.5 |
Schistosoma mansoni | amine oxidase | 0.0197 | 0.0879 | 0.0879 |
Brugia malayi | amine oxidase, flavin-containing family protein | 0.0197 | 0.0879 | 1 |
Toxoplasma gondii | histone lysine-specific demethylase | 0.0197 | 0.0879 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.0879 | 1 |
Schistosoma mansoni | amine oxidase | 0.0197 | 0.0879 | 0.0879 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.0879 | 1 |
Brugia malayi | hypothetical protein | 0.0197 | 0.0879 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0197 | 0.0879 | 0.5 |
Plasmodium vivax | lysine-specific histone demethylase 1, putative | 0.0197 | 0.0879 | 0.5 |
Schistosoma mansoni | tyrosine kinase | 0.0158 | 0.0603 | 0.0603 |
Echinococcus multilocularis | 0.0197 | 0.0879 | 0.0879 | |
Schistosoma mansoni | tyrosine kinase | 0.0158 | 0.0603 | 0.0603 |
Schistosoma mansoni | Lysine-specific histone demethylase 1 | 0.0197 | 0.0879 | 0.0879 |
Plasmodium falciparum | lysine-specific histone demethylase 1, putative | 0.0197 | 0.0879 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0197 | 0.0879 | 0.5 |
Mycobacterium leprae | PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) | 0.1501 | 1 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0158 | 0.0603 | 0.6867 |
Echinococcus granulosus | insulin receptor | 0.0158 | 0.0603 | 0.07 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0197 | 0.0879 | 0.5 |
Toxoplasma gondii | histone lysine-specific demethylase LSD1/BHC110/KDMA1A | 0.0197 | 0.0879 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0087 | 0.0109 | 0.1238 |
Plasmodium falciparum | conserved Plasmodium protein, unknown function | 0.0197 | 0.0879 | 0.5 |
Mycobacterium ulcerans | protoporphyrinogen oxidase | 0.1501 | 1 | 1 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0158 | 0.0603 | 0.6867 |
Leishmania major | UDP-galactopyranose mutase | 0.0197 | 0.0879 | 0.5 |
Brugia malayi | SWIRM domain containing protein | 0.0197 | 0.0879 | 1 |
Echinococcus granulosus | protoporphyrinogen oxidase | 0.1303 | 0.8618 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.01 | 0.1137 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0158 | 0.0603 | 0.0603 |
Echinococcus multilocularis | insulin receptor | 0.0158 | 0.0603 | 0.0603 |
Echinococcus multilocularis | lysine specific histone demethylase 1A | 0.0197 | 0.0879 | 0.0879 |
Trypanosoma cruzi | UDP-galactopyranose mutase | 0.0197 | 0.0879 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.0879 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.0879 | 1 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0197 | 0.0879 | 0.1019 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.0879 | 1 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0158 | 0.0603 | 0.07 |
Plasmodium vivax | protoporphyrinogen oxidase, putative | 0.0197 | 0.0879 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.0879 | 1 |
Echinococcus multilocularis | protoporphyrinogen oxidase | 0.1501 | 1 | 1 |
Mycobacterium tuberculosis | Probable protoporphyrinogen oxidase HemY (protoporphyrinogen-IX oxidase) (protoporphyrinogenase) (PPO) | 0.1303 | 0.8618 | 1 |
Echinococcus granulosus | lysine specific histone demethylase 1A | 0.0197 | 0.0879 | 0.1019 |
Schistosoma mansoni | Protoporphyrinogen oxidase chloroplast/mitochondrial precursor | 0.1501 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.