Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Papain family cysteine protease containing protein | 0.0404 | 0.2733 | 0.2733 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1205 | 1 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0404 | 0.2733 | 0.2733 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0404 | 0.2733 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0404 | 0.2733 | 0.2733 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0225 | 0.1108 | 0.1108 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0122 | 0.018 | 0.018 |
Echinococcus multilocularis | cysteine protease | 0.0404 | 0.2733 | 0.2733 |
Onchocerca volvulus | 0.0404 | 0.2733 | 1 | |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0404 | 0.2733 | 0.2733 |
Entamoeba histolytica | cysteine protease, putative | 0.0404 | 0.2733 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0225 | 0.1108 | 0.4054 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0107 | 0.0039 | 0.0039 |
Toxoplasma gondii | cathepsin B | 0.0443 | 0.3093 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0404 | 0.2733 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Entamoeba histolytica | cysteine protease, putative | 0.0225 | 0.1108 | 0.4054 |
Brugia malayi | cathepsin L-like precursor | 0.0282 | 0.1625 | 0.1625 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.018 | 0.018 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0404 | 0.2733 | 0.8189 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1205 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0107 | 0.0039 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0404 | 0.2733 | 0.2733 |
Plasmodium vivax | vivapain-1 | 0.0225 | 0.1108 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0225 | 0.1108 | 0.4054 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0404 | 0.2733 | 0.8189 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1205 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0225 | 0.1108 | 0.4054 |
Echinococcus multilocularis | cathepsin b | 0.1205 | 1 | 1 |
Brugia malayi | carbohydrate phosphorylase | 0.0107 | 0.0039 | 0.0039 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1205 | 1 | 1 |
Echinococcus granulosus | cathepsin L | 0.0225 | 0.1108 | 0.1108 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0225 | 0.1108 | 0.4054 |
Loa Loa (eye worm) | fibroinase | 0.0404 | 0.2733 | 0.2733 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0443 | 0.3093 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.0225 | 0.1108 | 0.4054 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1625 | 0.1625 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0404 | 0.2733 | 0.8189 |
Echinococcus multilocularis | cysteine protease | 0.0404 | 0.2733 | 0.2733 |
Brugia malayi | Cathepsin L-like precursor | 0.0122 | 0.018 | 0.018 |
Loa Loa (eye worm) | ctsf protein | 0.0404 | 0.2733 | 0.2733 |
Echinococcus granulosus | cathepsin l1 | 0.0404 | 0.2733 | 0.2733 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0404 | 0.2733 | 0.2733 |
Brugia malayi | Cathepsin L-like precursor | 0.0404 | 0.2733 | 0.2733 |
Echinococcus granulosus | cysteine protease | 0.0225 | 0.1108 | 0.1108 |
Entamoeba histolytica | cysteine protease, putative | 0.0225 | 0.1108 | 0.4054 |
Echinococcus granulosus | cathepsin b | 0.1205 | 1 | 1 |
Onchocerca volvulus | 0.0404 | 0.2733 | 1 | |
Onchocerca volvulus | 0.0404 | 0.2733 | 1 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0225 | 0.1108 | 0.1108 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Trypanosoma cruzi | cysteine protease, putative | 0.0225 | 0.1108 | 0.1108 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0443 | 0.3093 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.0225 | 0.1108 | 0.1108 |
Giardia lamblia | Cathepsin B precursor | 0.0443 | 0.3093 | 1 |
Plasmodium vivax | vivapain-3 | 0.0225 | 0.1108 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0282 | 0.1625 | 0.1625 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Onchocerca volvulus | Cathepsin L homolog | 0.0404 | 0.2733 | 1 |
Trypanosoma cruzi | cysteine peptidase (N-terminal), putative | 0.0225 | 0.1108 | 0.1108 |
Onchocerca volvulus | 0.0404 | 0.2733 | 1 | |
Echinococcus granulosus | cathepsin l1 | 0.0282 | 0.1625 | 0.1625 |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0887 | 0.7112 | 0.7112 |
Plasmodium vivax | vivapain-2 | 0.0404 | 0.2733 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0404 | 0.2733 | 0.2733 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0225 | 0.1108 | 0.1108 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0404 | 0.2733 | 0.2733 |
Brugia malayi | Cathepsin L-like precursor | 0.0282 | 0.1625 | 0.1625 |
Entamoeba histolytica | cysteine protease, putative | 0.0225 | 0.1108 | 0.4054 |
Chlamydia trachomatis | dipeptidase | 0.0549 | 0.4052 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0225 | 0.1108 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0282 | 0.1625 | 0.5255 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0107 | 0.0039 | 0.0144 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0282 | 0.1625 | 0.1625 |
Echinococcus granulosus | glycogen phosphorylase | 0.0107 | 0.0039 | 0.0039 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0107 | 0.0039 | 0.0039 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0404 | 0.2733 | 0.2733 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0443 | 0.3093 | 0.3093 |
Giardia lamblia | Glycogen phosphorylase | 0.0107 | 0.0039 | 0.0127 |
Brugia malayi | Cathepsin L-like precursor | 0.0404 | 0.2733 | 0.2733 |
Mycobacterium ulcerans | hypothetical protein | 0.0549 | 0.4052 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.018 | 0.018 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1625 | 0.1625 |
Plasmodium vivax | unspecified product | 0.0122 | 0.018 | 0.066 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0225 | 0.1108 | 0.1108 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0107 | 0.0039 | 0.0144 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0122 | 0.018 | 0.018 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0122 | 0.018 | 0.018 |
Onchocerca volvulus | Cathepsin L homolog | 0.0404 | 0.2733 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.018 | 0.018 |
Plasmodium vivax | unspecified product | 0.0225 | 0.1108 | 0.4054 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0404 | 0.2733 | 0.2733 |
Plasmodium vivax | vivapain-2 | 0.0404 | 0.2733 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0282 | 0.1625 | 0.5255 |
Loa Loa (eye worm) | cysteine protease | 0.0404 | 0.2733 | 0.2733 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0404 | 0.2733 | 0.2733 |
Loa Loa (eye worm) | hypothetical protein | 0.0282 | 0.1625 | 0.1625 |
Giardia lamblia | Cathepsin B precursor | 0.0443 | 0.3093 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0225 | 0.1108 | 0.4054 |
Brugia malayi | Cathepsin L-like precursor | 0.0404 | 0.2733 | 0.2733 |
Entamoeba histolytica | cysteine protease, putative | 0.0225 | 0.1108 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0225 | 0.1108 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0225 | 0.1108 | 0.3583 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0107 | 0.0039 | 0.0144 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0107 | 0.0039 | 0.0039 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0404 | 0.2733 | 0.2733 |
Schistosoma mansoni | cathepsin s | 0.0122 | 0.018 | 0.018 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0225 | 0.1108 | 0.1108 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0443 | 0.3093 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0404 | 0.2733 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0107 | 0.0039 | 0.0039 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0282 | 0.1625 | 0.1625 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0225 | 0.1108 | 0.4054 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0404 | 0.2733 | 1 |
Onchocerca volvulus | 0.0404 | 0.2733 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0404 | 0.2733 | 0.8189 |
Plasmodium falciparum | cysteine proteinase falcipain 1 | 0.0225 | 0.1108 | 0.4054 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0404 | 0.2733 | 0.2733 |
Echinococcus multilocularis | cathepsin b | 0.1205 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0225 | 0.1108 | 0.4054 |
Entamoeba histolytica | cysteine protease, putative | 0.0225 | 0.1108 | 0.4054 |
Echinococcus granulosus | cathepsin b | 0.1205 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1205 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0404 | 0.2733 | 0.8189 |
Brugia malayi | Cathepsin L-like precursor | 0.0404 | 0.2733 | 0.2733 |
Entamoeba histolytica | cysteine protease, putative | 0.0225 | 0.1108 | 0.4054 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1205 | 1 | 1 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0107 | 0.0039 | 0.0127 |
Echinococcus granulosus | glycogen phosphorylase | 0.0107 | 0.0039 | 0.0039 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0225 | 0.1108 | 0.1108 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0443 | 0.3093 | 0.3093 |
Trypanosoma cruzi | cysteine proteinase, putative | 0.0225 | 0.1108 | 0.1108 |
Entamoeba histolytica | cysteine protease, putative | 0.0225 | 0.1108 | 0.4054 |
Schistosoma mansoni | glycogen phosphorylase | 0.0107 | 0.0039 | 0.0039 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0404 | 0.2733 | 0.2733 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0404 | 0.2733 | 1 |
Onchocerca volvulus | 0.0282 | 0.1625 | 0.5946 | |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0107 | 0.0039 | 0.0039 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0404 | 0.2733 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Loa Loa (eye worm) | cathepsin B | 0.0443 | 0.3093 | 0.3093 |
Toxoplasma gondii | cathepsin CPL | 0.0404 | 0.2733 | 0.8838 |
Onchocerca volvulus | Cathepsin F homolog | 0.0404 | 0.2733 | 1 |
Brugia malayi | cathepsin L-like cysteine proteinase, identical | 0.0122 | 0.018 | 0.018 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0122 | 0.018 | 0.018 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0404 | 0.2733 | 0.8189 |
Entamoeba histolytica | cysteine proteinase 2 | 0.0225 | 0.1108 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Giardia lamblia | Cathepsin B precursor | 0.0443 | 0.3093 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0282 | 0.1625 | 0.5946 |
Brugia malayi | Cathepsin L-like precursor | 0.0404 | 0.2733 | 0.2733 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0404 | 0.2733 | 0.2733 |
Onchocerca volvulus | 0.0404 | 0.2733 | 1 | |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0404 | 0.2733 | 0.2733 |
Onchocerca volvulus | 0.0404 | 0.2733 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0404 | 0.2733 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0404 | 0.2733 | 0.8189 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.0225 | 0.1108 | 0.1108 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0225 | 0.1108 | 0.3583 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0404 | 0.2733 | 0.8189 |
Brugia malayi | Cathepsin L-like precursor | 0.0404 | 0.2733 | 0.2733 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0282 | 0.1625 | 0.1625 |
Echinococcus multilocularis | cathepsin L | 0.0225 | 0.1108 | 0.1108 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0404 | 0.2733 | 0.2733 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0404 | 0.2733 | 0.8189 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0225 | 0.1108 | 0.4054 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0404 | 0.2733 | 0.8838 |
Schistosoma mansoni | glycogen phosphorylase | 0.0107 | 0.0039 | 0.0039 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.