Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0068 | 0.2265 | 0.2265 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.0225 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.2265 | 0.2265 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.008 | 0.008 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0093 | 0.3458 | 0.3458 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.2345 | 0.2345 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.008 | 0.008 |
Echinococcus multilocularis | lysosomal protective protein | 0.0225 | 1 | 1 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0093 | 0.3458 | 0.5 |
Toxoplasma gondii | peptidase family M13 protein | 0.0093 | 0.3458 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.0225 | 1 | 0.5 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0024 | 0.008 | 0.008 |
Schistosoma mansoni | neprilysin-2 (M13 family) | 0.0047 | 0.1193 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.2345 | 0.2345 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.0225 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.3458 | 0.3458 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.3458 | 0.3458 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0047 | 0.1193 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.2345 | 0.2345 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.008 | 0.008 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.2265 | 0.2265 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S10 | 0.0225 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.2345 | 0.2345 |
Brugia malayi | Hypothetical zinc metalloproteinase T16A9.4 | 0.0093 | 0.3458 | 0.3458 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.2265 | 0.2265 |
Echinococcus granulosus | lysosomal protective protein | 0.0225 | 1 | 1 |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0047 | 0.1193 | 0.1193 |
Schistosoma mansoni | Nep2 peptidase (M13 family) | 0.0047 | 0.1193 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.2345 | 0.2345 |
Loa Loa (eye worm) | hypothetical protein | 0.0093 | 0.3458 | 0.3458 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.1151 | 0.1151 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0093 | 0.3458 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.2265 | 0.2265 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.008 | 0.008 |
Onchocerca volvulus | Uncharacterized serine carboxypeptidase homolog | 0.0225 | 1 | 1 |
Brugia malayi | Peptidase family M13 containing protein | 0.0093 | 0.3458 | 0.3458 |
Schistosoma mansoni | neprilysin | 0.0024 | 0.008 | 0.008 |
Trypanosoma cruzi | serine carboxypeptidase (CBP1), putative | 0.0225 | 1 | 0.5 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0093 | 0.3458 | 0.5 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0068 | 0.2265 | 0.2265 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.008 | 0.008 |
Leishmania major | serine carboxypeptidase (CBP1), putative,serine peptidase, Clan SC, Family S10 | 0.0225 | 1 | 0.5 |
Echinococcus multilocularis | family S10 non peptidase ue (S10 family) | 0.0203 | 0.8902 | 0.8321 |
Schistosoma mansoni | hypothetical protein | 0.0024 | 0.008 | 0.008 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.0225 | 1 | 0.5 |
Echinococcus granulosus | family S10 non peptidase ue S10 family | 0.0203 | 0.8902 | 0.8321 |
Schistosoma mansoni | family M13 non-peptidase homologue (M13 family) | 0.0047 | 0.1193 | 0.1193 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.2345 | 0.2345 |
Schistosoma mansoni | family S10 unassigned peptidase (S10 family) | 0.0225 | 1 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S10, putative | 0.0225 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0225 | 1 | 1 |
Schistosoma mansoni | family S10 non-peptidase homologue (S10 family) | 0.0225 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.