Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | SEA domain containing protein | 0.0044 | 0.0224 | 0.0224 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0052 | 0.039 | 0.0626 |
Leishmania major | hypothetical protein, conserved | 0.0073 | 0.0831 | 0.1658 |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0044 | 0.0221 | 0.0637 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0048 | 0.0308 | 0.0888 |
Mycobacterium ulcerans | hypothetical protein | 0.0044 | 0.0221 | 0.0137 |
Brugia malayi | Trypsin family protein | 0.0044 | 0.0221 | 0.0221 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0044 | 0.0221 | 0.0637 |
Plasmodium vivax | DNA topoisomerase II, putative | 0.0149 | 0.2419 | 0.698 |
Echinococcus granulosus | nmda type glutamate receptor | 0.01 | 0.1401 | 0.4043 |
Loa Loa (eye worm) | hypothetical protein | 0.0194 | 0.3341 | 0.567 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0075 | 0.0863 | 0.2492 |
Schistosoma mansoni | DNA topoisomerase type I | 0.02 | 0.3465 | 0.5565 |
Echinococcus multilocularis | glutamate receptor, ionotrophic, AMPA 3 | 0.0075 | 0.0863 | 0.2492 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0067 | 0.0716 | 0.1083 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0194 | 0.3341 | 0.5366 |
Leishmania major | hypothetical protein, conserved | 0.0073 | 0.0831 | 0.1658 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Trypanosoma brucei | DNA topoisomerase II beta, putative | 0.0141 | 0.2251 | 0.5585 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0221 | 0.0355 |
Mycobacterium tuberculosis | DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (type II DNA topoisomerase) | 0.0087 | 0.1126 | 0.1856 |
Brugia malayi | Trypsin family protein | 0.0044 | 0.0221 | 0.0221 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0075 | 0.0863 | 0.2492 |
Loa Loa (eye worm) | DNA topoisomerase I | 0.02 | 0.3465 | 0.5881 |
Echinococcus multilocularis | glutamate receptor NMDA | 0.0084 | 0.1067 | 0.3079 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0831 | 0.1658 |
Treponema pallidum | DNA gyrase, subunit B (gyrB) | 0.0087 | 0.1126 | 0.3075 |
Brugia malayi | Muscle positioning protein 4 | 0.0044 | 0.0224 | 0.0224 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0075 | 0.0863 | 0.2492 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0168 | 0.2798 | 0.7888 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0221 | 0.0375 |
Onchocerca volvulus | 0.0044 | 0.0224 | 0.038 | |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0067 | 0.0716 | 0.1293 |
Echinococcus multilocularis | DNA topoisomerase 1 | 0.02 | 0.3465 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0831 | 0.1658 |
Brugia malayi | DNA topoisomerase I | 0.02 | 0.3465 | 0.3465 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0578 | 0.0982 |
Schistosoma mansoni | hypothetical protein | 0.0048 | 0.0308 | 0.0494 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0067 | 0.0716 | 0.2066 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 3 | 0.0071 | 0.0793 | 0.229 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0044 | 0.0221 | 0.0355 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Plasmodium vivax | DNA gyrase subunit B, putative | 0.0087 | 0.1126 | 0.3248 |
Brugia malayi | DNA gyrase/topoisomerase IV, A subunit family protein | 0.0149 | 0.2419 | 0.2419 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Onchocerca volvulus | 0.0044 | 0.0221 | 0.0375 | |
Echinococcus granulosus | amiloride sensitive amine oxidase | 0.0091 | 0.1211 | 0.3496 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0048 | 0.0308 | 0.0888 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0194 | 0.3341 | 0.5366 |
Brugia malayi | Protein kinase domain containing protein | 0.0048 | 0.0308 | 0.0308 |
Leishmania major | mitochondrial DNA topoisomerase II | 0.0168 | 0.2798 | 0.7888 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0831 | 0.1658 |
Schistosoma mansoni | ATP-binding cassette transporter | 0.0058 | 0.0529 | 0.085 |
Brugia malayi | glutathione reductase | 0.0067 | 0.0716 | 0.0716 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0058 | 0.0529 | 0.085 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.01 | 0.1401 | 0.4043 |
Trypanosoma cruzi | mitochondrial DNA topoisomerase II, putative | 0.0168 | 0.2798 | 0.7888 |
Trypanosoma cruzi | membrane transporter protein, putative | 0.0073 | 0.0831 | 0.1658 |
Wolbachia endosymbiont of Brugia malayi | DNA gyrase, topoisomerase II, B subunit, GyrB | 0.0087 | 0.1126 | 0.5 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0048 | 0.0308 | 0.0522 |
Onchocerca volvulus | 0.0044 | 0.0224 | 0.038 | |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0075 | 0.0863 | 0.2492 |
Echinococcus multilocularis | potassium voltage gated channel subfamily H | 0.0039 | 0.0135 | 0.0391 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0039 | 0.0135 | 0.023 |
Toxoplasma gondii | kringle domain-containing protein | 0.0048 | 0.0308 | 0.0888 |
Brugia malayi | Probable DNA topoisomerase II | 0.0149 | 0.2419 | 0.2419 |
Onchocerca volvulus | 0.0044 | 0.0224 | 0.038 | |
Trypanosoma brucei | membrane transporter protein, putative | 0.0073 | 0.0831 | 0.0419 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Plasmodium vivax | topoisomerase I, putative | 0.02 | 0.3465 | 1 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0317 | 0.5892 | 0.9463 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0831 | 0.1658 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0224 | 0.0359 |
Echinococcus multilocularis | DNA topoisomerase 2 alpha | 0.0149 | 0.2419 | 0.698 |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0044 | 0.0221 | 0.0637 |
Brugia malayi | DNA topoisomerase II, alpha isozyme | 0.0149 | 0.2419 | 0.2419 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.1416 | 0.2403 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0221 | 0.0375 |
Chlamydia trachomatis | glutamine binding protein | 0.004 | 0.0142 | 0.1261 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0043 | 0.0212 | 0.0612 |
Plasmodium falciparum | DNA gyrase subunit B | 0.0087 | 0.1126 | 0.3248 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.0308 | 0.0522 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0194 | 0.3341 | 0.567 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0073 | 0.0831 | 0.1658 |
Loa Loa (eye worm) | glutamate receptor 1 | 0.0058 | 0.0529 | 0.0899 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0044 | 0.0221 | 0.0221 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0101 | 0.1413 | 0.2398 |
Schistosoma mansoni | DNA topoisomerase II | 0.0149 | 0.2419 | 0.3884 |
Brugia malayi | Kringle domain containing protein | 0.0048 | 0.0308 | 0.0308 |
Schistosoma mansoni | multidrug resistance protein | 0.0073 | 0.0831 | 0.1335 |
Echinococcus granulosus | Mastin | 0.0044 | 0.0221 | 0.0637 |
Loa Loa (eye worm) | DOMON domain-containing protein | 0.0044 | 0.0224 | 0.038 |
Schistosoma mansoni | hypothetical protein | 0.0044 | 0.0221 | 0.0355 |
Echinococcus granulosus | serotonin transporter | 0.0194 | 0.3341 | 0.9642 |
Brugia malayi | Glutamate receptor 1 precursor | 0.0058 | 0.0529 | 0.0529 |
Schistosoma mansoni | DNA topoisomerase type I | 0.02 | 0.3465 | 0.5565 |
Entamoeba histolytica | DNA topoisomerase II, putative | 0.0149 | 0.2419 | 0.5 |
Trypanosoma brucei | MATE efflux family protein, putative | 0.0073 | 0.0831 | 0.0419 |
Onchocerca volvulus | 0.0044 | 0.0224 | 0.038 | |
Echinococcus multilocularis | enteropeptidase | 0.0044 | 0.0221 | 0.0637 |
Loa Loa (eye worm) | hypothetical protein | 0.0194 | 0.3341 | 0.567 |
Echinococcus granulosus | Glutamate receptor ionotropic kainate 2 | 0.0075 | 0.0863 | 0.2492 |
Echinococcus granulosus | glutamate receptor 2 | 0.0043 | 0.0212 | 0.0612 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0221 | 0.0375 |
Loa Loa (eye worm) | glutamate receptor 2 | 0.0058 | 0.0529 | 0.0899 |
Trypanosoma brucei | membrane transporter protein, putative | 0.0073 | 0.0831 | 0.0419 |
Schistosoma mansoni | hypothetical protein | 0.0091 | 0.1211 | 0.1946 |
Onchocerca volvulus | Putative DNA topoisomerase 2, mitochondrial | 0.0101 | 0.1413 | 0.2398 |
Plasmodium falciparum | glutathione reductase | 0.0067 | 0.0716 | 0.2066 |
Brugia malayi | Glutamate receptor 2 precursor | 0.0058 | 0.0529 | 0.0529 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0044 | 0.0221 | 0.0637 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0069 | 0.0746 | 0.6627 |
Loa Loa (eye worm) | serotonin transporter b | 0.0194 | 0.3341 | 0.567 |
Chlamydia trachomatis | DNA gyrase subunit B | 0.0087 | 0.1126 | 1 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0039 | 0.0135 | 0.0391 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0067 | 0.0716 | 0.1215 |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0075 | 0.0863 | 0.2492 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Schistosoma mansoni | copper/topaquinone oxidase | 0.0091 | 0.1211 | 0.1946 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0155 | 0.2543 | 0.734 |
Plasmodium vivax | glutathione reductase, putative | 0.0067 | 0.0716 | 0.2066 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0027 | 0.0046 |
Onchocerca volvulus | DNA topoisomerase 2 homolog | 0.0101 | 0.1413 | 0.2398 |
Mycobacterium leprae | Probable DNA gyrase (subunit B) GyrB (DNA topoisomerase (ATP-hydrolysing)) (DNA topoisomerase II) (Type II DNA topoisomerase) | 0.0039 | 0.0123 | 0.5 |
Echinococcus multilocularis | amiloride sensitive amine oxidase | 0.0091 | 0.1211 | 0.3496 |
Onchocerca volvulus | 0.0044 | 0.0221 | 0.0375 | |
Brugia malayi | Thioredoxin reductase | 0.0067 | 0.0716 | 0.0716 |
Echinococcus multilocularis | serotonin transporter | 0.0194 | 0.3341 | 0.9642 |
Echinococcus multilocularis | multidrug and toxin extrusion protein 2 | 0.0073 | 0.0831 | 0.2399 |
Plasmodium falciparum | thioredoxin reductase | 0.0067 | 0.0716 | 0.2066 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0048 | 0.0308 | 0.0888 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0044 | 0.0221 | 0.0221 |
Schistosoma mansoni | glutamate receptor kainate | 0.0058 | 0.0529 | 0.085 |
Toxoplasma gondii | thioredoxin reductase | 0.0067 | 0.0716 | 0.2066 |
Schistosoma mansoni | glutamate receptor kainate | 0.0058 | 0.0529 | 0.085 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0317 | 0.5906 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Trypanosoma brucei | DNA topoisomerase II alpha, putative | 0.0141 | 0.2251 | 0.5585 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0117 | 0.1754 | 0.5063 |
Giardia lamblia | DNA topoisomerase II | 0.0142 | 0.2257 | 0.5 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0067 | 0.0716 | 0.2066 |
Leishmania major | acetyltransferase-like protein | 0.0111 | 0.1624 | 0.4169 |
Schistosoma mansoni | amine GPCR | 0.02 | 0.3467 | 0.5568 |
Trichomonas vaginalis | DNA topoisomerase II, putative | 0.0149 | 0.2419 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.1416 | 0.2403 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0048 | 0.0308 | 0.0888 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0043 | 0.0211 | 0.0338 |
Trypanosoma brucei | DNA topoisomerase IB, large subunit | 0.02 | 0.3465 | 1 |
Onchocerca volvulus | 0.0044 | 0.0221 | 0.0375 | |
Toxoplasma gondii | DNA topoisomerase 2, putative | 0.0149 | 0.2419 | 0.698 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0117 | 0.1754 | 0.2818 |
Mycobacterium ulcerans | acetyltransferase | 0.0111 | 0.1624 | 0.2571 |
Brugia malayi | Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog | 0.0039 | 0.0135 | 0.0135 |
Trypanosoma brucei | DNA topoisomerase ii | 0.0168 | 0.2798 | 0.7575 |
Schistosoma mansoni | glutamate receptor kainate | 0.0058 | 0.0529 | 0.085 |
Leishmania major | DNA topoisomerase IB, large subunit | 0.02 | 0.3465 | 1 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0159 | 0.2613 | 0.4198 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Schistosoma mansoni | DNA topoisomerase type I | 0.02 | 0.3465 | 0.5565 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0141 | 0.2251 | 0.6156 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0333 | 0.6226 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0046 | 0.0274 | 0.0791 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0578 | 0.0982 |
Toxoplasma gondii | ATPase/histidine kinase/DNA gyrase B/HSP90 domain-containing protein | 0.0087 | 0.1126 | 0.3248 |
Loa Loa (eye worm) | TOPoisomerase family member | 0.0149 | 0.2419 | 0.4105 |
Plasmodium falciparum | topoisomerase I | 0.02 | 0.3465 | 1 |
Echinococcus granulosus | glutamate receptor 2 | 0.0075 | 0.0863 | 0.2492 |
Onchocerca volvulus | 0.0044 | 0.0224 | 0.038 | |
Onchocerca volvulus | 0.0044 | 0.0221 | 0.0375 | |
Trypanosoma cruzi | DNA topoisomerase IB, large subunit, putative | 0.02 | 0.3465 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0224 | 0.038 |
Schistosoma mansoni | glutamate receptor AMPA | 0.0058 | 0.0529 | 0.085 |
Loa Loa (eye worm) | hypothetical protein | 0.0194 | 0.3341 | 0.567 |
Onchocerca volvulus | 0.0273 | 0.4988 | 0.8466 | |
Echinococcus multilocularis | Glutamate receptor, ionotropic kainate 2 | 0.0075 | 0.0863 | 0.2492 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0044 | 0.0221 | 0.0637 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0044 | 0.0221 | 0.0637 |
Loa Loa (eye worm) | trypsin family protein | 0.0044 | 0.0221 | 0.0375 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0224 | 0.038 |
Plasmodium falciparum | DNA topoisomerase 2 | 0.0149 | 0.2419 | 0.698 |
Onchocerca volvulus | 0.0194 | 0.3341 | 0.567 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Leishmania major | trypanothione reductase | 0.0067 | 0.0716 | 0.1293 |
Echinococcus multilocularis | Mastin | 0.0044 | 0.0221 | 0.0637 |
Loa Loa (eye worm) | glutathione reductase | 0.0067 | 0.0716 | 0.1215 |
Schistosoma mansoni | voltage-gated potassium channel | 0.0043 | 0.0211 | 0.0338 |
Echinococcus granulosus | enteropeptidase | 0.0044 | 0.0221 | 0.0637 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0221 | 0.0375 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0044 | 0.0221 | 0.0637 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Onchocerca volvulus | 0.0048 | 0.0308 | 0.0522 | |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0067 | 0.0716 | 0.2066 |
Loa Loa (eye worm) | hypothetical protein | 0.0317 | 0.5892 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0317 | 0.5892 | 1 |
Onchocerca volvulus | 0.0044 | 0.0221 | 0.0375 | |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0044 | 0.0221 | 0.0355 |
Mycobacterium ulcerans | flavin-containing monoamine oxidase AofH | 0.0317 | 0.5906 | 1 |
Leishmania major | DNA topoisomerase ii | 0.0141 | 0.2251 | 0.6156 |
Chlamydia trachomatis | arginine ABC transporter substrate-binding protein ArtJ | 0.004 | 0.0142 | 0.1261 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0044 | 0.0221 | 0.0637 |
Toxoplasma gondii | DNA topoisomerase I, putative | 0.02 | 0.3465 | 1 |
Echinococcus multilocularis | Multi antimicrobial extrusion protein MatE | 0.0067 | 0.0698 | 0.2016 |
Echinococcus multilocularis | glutamate receptor 2 | 0.0058 | 0.0529 | 0.1528 |
Mycobacterium tuberculosis | Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) | 0.0295 | 0.5442 | 1 |
Trypanosoma brucei | membrane transporter protein, putative | 0.0073 | 0.0831 | 0.0419 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0221 | 0.0375 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0117 | 0.1754 | 0.5063 |
Echinococcus granulosus | multidrug and toxin extrusion protein 2 | 0.0073 | 0.0831 | 0.2399 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0194 | 0.3341 | 1 |
Brugia malayi | Trypsin family protein | 0.0317 | 0.5892 | 0.5892 |
Echinococcus granulosus | DNA topoisomerase 2 alpha | 0.0149 | 0.2419 | 0.698 |
Echinococcus granulosus | glutamate receptor NMDA | 0.0084 | 0.1067 | 0.3079 |
Echinococcus granulosus | DNA topoisomerase 1 | 0.02 | 0.3465 | 1 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0194 | 0.3341 | 0.567 |
Echinococcus granulosus | glutamate receptor ionotrophic AMPA 3 | 0.0075 | 0.0863 | 0.2492 |
Onchocerca volvulus | 0.0317 | 0.5892 | 1 | |
Echinococcus granulosus | nmda type glutamate receptor | 0.0155 | 0.2543 | 0.734 |
Brugia malayi | Trypsin family protein | 0.0044 | 0.0221 | 0.0221 |
Trypanosoma cruzi | DNA topoisomerase II, putative | 0.0141 | 0.2251 | 0.6156 |
Mycobacterium ulcerans | DNA gyrase subunit B | 0.0087 | 0.1126 | 0.1706 |
Brugia malayi | hypothetical protein | 0.0044 | 0.0221 | 0.0221 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0194 | 0.3341 | 0.3341 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.