Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0245 | 0.0138 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0011 | 0.1201 | 0.2156 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0011 | 0.1201 | 0.2304 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.1201 | 0.2304 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0011 | 0.1201 | 0.2156 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.1201 | 0.2304 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0005 | 0.0245 | 0.0138 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0525 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0011 | 0.1201 | 0.2304 |
Onchocerca volvulus | 0.0011 | 0.1201 | 0.2304 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1201 | 0.2304 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0057 | 0.8867 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0348 | 0.0247 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0011 | 0.1201 | 0.2156 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0011 | 0.1201 | 0.1104 |
Schistosoma mansoni | nuclear hormone receptor | 0.0011 | 0.1201 | 0.1104 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0011 | 0.1201 | 0.2304 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.092 | 0.1626 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0011 | 0.1201 | 0.2304 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0011 | 0.1201 | 0.2304 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.1201 | 0.2304 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0011 | 0.1201 | 0.2304 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0011 | 0.1201 | 0.2156 |
Schistosoma mansoni | coup transcription factor | 0.0011 | 0.1201 | 0.1104 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0348 | 0.0247 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0634 | 0.0878 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0006 | 0.0348 | 0.0231 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0011 | 0.1201 | 0.2304 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0525 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0011 | 0.1201 | 0.2304 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.1201 | 0.1104 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0011 | 0.1201 | 0.2304 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.003 | 0.4393 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0011 | 0.1201 | 0.2304 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1201 | 0.2304 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.1201 | 0.2156 |
Brugia malayi | nuclear receptor NHR-88 | 0.0011 | 0.1201 | 0.2304 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.1566 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.4678 | 0.4619 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4393 | 0.4331 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0011 | 0.1201 | 0.2304 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0011 | 0.1201 | 0.2304 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.1201 | 0.2156 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0939 | 0.1673 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0011 | 0.1201 | 0.2156 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0348 | 0.0247 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0011 | 0.1201 | 0.2304 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Brugia malayi | nuclear receptor RXR | 0.0006 | 0.0348 | 0.0247 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0245 | 0.0138 |
Schistosoma mansoni | thyroid hormone receptor | 0.0011 | 0.1201 | 0.1104 |
Schistosoma mansoni | cpg binding protein | 0.0032 | 0.4678 | 0.4619 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.1201 | 0.2156 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.1201 | 0.2156 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0011 | 0.1201 | 0.1104 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0348 | 0.0247 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0006 | 0.0348 | 0.0247 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1201 | 0.2304 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0348 | 0.0247 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0011 | 0.1201 | 0.1104 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0011 | 0.1201 | 0.2304 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.1566 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0011 | 0.1201 | 0.2156 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0006 | 0.0348 | 0.0247 |
Brugia malayi | steroid hormone receptor | 0.0011 | 0.1201 | 0.2304 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0011 | 0.1201 | 0.2156 |
Echinococcus granulosus | cpg binding protein | 0.0032 | 0.4678 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0348 | 0.0247 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0634 | 0.0878 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0011 | 0.1201 | 0.2304 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1201 | 0.2304 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0006 | 0.0348 | 0.0241 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0011 | 0.1201 | 0.2304 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0006 | 0.0348 | 0.0231 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0011 | 0.1201 | 0.2304 |
Brugia malayi | CXXC zinc finger family protein | 0.003 | 0.4393 | 1 |
Onchocerca volvulus | 0.003 | 0.4393 | 1 | |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0005 | 0.0245 | 0.0138 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0005 | 0.0245 | 0.0138 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0011 | 0.1201 | 0.2304 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0011 | 0.1201 | 0.2304 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0245 | 0.0138 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0011 | 0.1201 | 0.1104 |
Brugia malayi | ecdysteroid receptor | 0.0011 | 0.1201 | 0.2304 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0011 | 0.1201 | 0.2156 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0011 | 0.1201 | 0.1104 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0011 | 0.1201 | 0.1104 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0634 | 0.0531 |
Loa Loa (eye worm) | hypothetical protein | 0.0006 | 0.0348 | 0.0247 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0634 | 0.0878 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0011 | 0.1201 | 0.1104 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0525 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0011 | 0.1201 | 0.1104 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0011 | 0.1201 | 0.2156 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1201 | 0.2304 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Brugia malayi | hypothetical protein | 0.0006 | 0.0348 | 0.0247 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.1201 | 0.2156 |
Echinococcus granulosus | FTZ F1 alpha | 0.0011 | 0.1201 | 0.2156 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0005 | 0.0245 | 0.0138 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0011 | 0.1201 | 0.2304 |
Echinococcus multilocularis | cpg binding protein | 0.0032 | 0.4678 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1201 | 0.2304 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0006 | 0.0348 | 0.0241 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0245 | 0.0138 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1201 | 0.2304 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.1201 | 0.2304 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0634 | 0.0878 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0011 | 0.1201 | 0.2156 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0011 | 0.1201 | 0.2304 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0011 | 0.1201 | 0.2304 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0011 | 0.1201 | 0.2156 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0011 | 0.1201 | 0.1104 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0011 | 0.1201 | 0.2304 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0011 | 0.1201 | 0.2304 |
Brugia malayi | nuclear hormone receptor | 0.0011 | 0.1201 | 0.2304 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0011 | 0.1201 | 0.2156 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.