Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | potassium channel subfamily K 8 | 0.0084 | 0.0152 | 0.0134 |
Echinococcus multilocularis | potassium channel subfamily K 8 | 0.0084 | 0.0152 | 0.0134 |
Echinococcus multilocularis | twik family of potassium channels | 0.0084 | 0.0152 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Leishmania major | telomerase reverse transcriptase, putative | 0.0086 | 0.0158 | 1 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0084 | 0.0152 | 0.0188 |
Echinococcus multilocularis | Two pore potassium channel protein sup 9 | 0.0084 | 0.0152 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | TWK-7 protein | 0.0084 | 0.0152 | 0.0165 |
Onchocerca volvulus | Telomerase reverse transcriptase homolog | 0.0313 | 0.1187 | 1 |
Schistosoma mansoni | calcium-activated potassium channel | 0.1648 | 0.7219 | 0.8895 |
Echinococcus multilocularis | potassium channel subfamily K | 0.0084 | 0.0152 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0456 | 0.183 | 0.2237 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Brugia malayi | Cache domain containing protein | 0.0456 | 0.183 | 1 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0084 | 0.0152 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Giardia lamblia | Telomerase catalytic subunit | 0.0086 | 0.0158 | 1 |
Echinococcus granulosus | voltage dependent calcium channel subunit | 0.1029 | 0.4423 | 0.4413 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0084 | 0.0152 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0084 | 0.0152 | 0.5 |
Echinococcus granulosus | calcium activated potassium channel variant | 0.0084 | 0.0152 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0411 | 0.163 | 0.199 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Entamoeba histolytica | calcium-gated potassium channel protein, putative | 0.0084 | 0.0152 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Schistosoma mansoni | hypothetical protein | 0.1846 | 0.8116 | 1 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0086 | 0.0158 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0084 | 0.0152 | 0.5 |
Echinococcus multilocularis | serotonin receptor | 0.0411 | 0.163 | 0.1614 |
Trypanosoma cruzi | telomerase reverse transcriptase, putative | 0.0086 | 0.0158 | 1 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0084 | 0.0152 | 0.0188 |
Echinococcus granulosus | potassium channel subfamily K | 0.0084 | 0.0152 | 0.0134 |
Loa Loa (eye worm) | uncoordinated protein 58 | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Schistosoma mansoni | calcium-activated potassium channel | 0.0084 | 0.0152 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Echinococcus granulosus | small conductance calcium activated potassium | 0.1846 | 0.8116 | 0.8112 |
Loa Loa (eye worm) | large conductance calcium-activated potassium channel alpha subunit ai | 0.0084 | 0.0152 | 0.0165 |
Plasmodium falciparum | telomerase reverse transcriptase | 0.0086 | 0.0158 | 1 |
Schistosoma mansoni | dihydropyridine-sensitive l-type calcium channel | 0.0498 | 0.202 | 0.2489 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Echinococcus multilocularis | twik family of potassium channels | 0.0084 | 0.0152 | 0.0134 |
Echinococcus multilocularis | voltage dependent calcium channel subunit | 0.1029 | 0.4423 | 0.4413 |
Schistosoma mansoni | hypothetical protein | 0.0532 | 0.2174 | 0.2678 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0084 | 0.0152 | 0.5 |
Echinococcus granulosus | potassium channel subfamily K 8 | 0.0084 | 0.0152 | 0.0134 |
Schistosoma mansoni | calcium-activated potassium channel | 0.1846 | 0.8116 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Echinococcus multilocularis | calcium activated potassium channel variant | 0.0084 | 0.0152 | 0.0134 |
Schistosoma mansoni | amine GPCR | 0.106 | 0.4562 | 0.5622 |
Echinococcus multilocularis | small conductance calcium activated potassium | 0.1846 | 0.8116 | 0.8112 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Trypanosoma brucei | telomerase reverse transcriptase | 0.0086 | 0.0158 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0084 | 0.0152 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0869 | 0.3696 | 0.4542 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0084 | 0.0152 | 0.5 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0084 | 0.0152 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Schistosoma mansoni | serine-rich repeat protein | 0.0532 | 0.2174 | 0.2678 |
Loa Loa (eye worm) | TWK-28 protein | 0.0084 | 0.0152 | 0.0165 |
Brugia malayi | Telomerase reverse transcriptase | 0.0228 | 0.08 | 0.386 |
Echinococcus granulosus | TWiK family of potassium channels protein 7 | 0.0084 | 0.0152 | 0.0134 |
Plasmodium vivax | telomerase reverse transcriptase, putative | 0.0086 | 0.0158 | 1 |
Echinococcus granulosus | twik family of potassium channels | 0.0084 | 0.0152 | 0.0134 |
Echinococcus granulosus | Two pore potassium channel protein sup 9 | 0.0084 | 0.0152 | 0.0134 |
Mycobacterium ulcerans | transmembrane cation transporter | 0.0084 | 0.0152 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Echinococcus granulosus | twik family of potassium channels | 0.0084 | 0.0152 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0084 | 0.0152 | 0.0188 |
Toxoplasma gondii | RNA-directed DNA polymerase | 0.0086 | 0.0158 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0411 | 0.163 | 0.199 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.0411 | 0.163 | 0.1614 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0084 | 0.0152 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0114 | 0.0286 | 0.0329 |
Mycobacterium tuberculosis | Possible transmembrane cation transporter | 0.0084 | 0.0152 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0084 | 0.0152 | 0.0188 |
Loa Loa (eye worm) | S-phase kinase-associated protein 1A | 0.0084 | 0.0152 | 0.0165 |
Echinococcus multilocularis | potassium channel subfamily K 8 | 0.0084 | 0.0152 | 0.0134 |
Echinococcus multilocularis | voltage dependent calcium channel subunit | 0.2263 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | potassium voltage-gated channel subfamily Q member 5 | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.0411 | 0.163 | 0.2009 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0084 | 0.0152 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Echinococcus multilocularis | serotonin receptor | 0.0411 | 0.163 | 0.1614 |
Schistosoma mansoni | dihydropyridine-sensitive l-type calcium channel | 0.0987 | 0.4233 | 0.5216 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Mycobacterium ulcerans | ion transport protein | 0.0084 | 0.0152 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Echinococcus multilocularis | TWiK family of potassium channels protein 7 | 0.0084 | 0.0152 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0152 | 0.0165 |
Loa Loa (eye worm) | hypothetical protein | 0.0779 | 0.3294 | 0.4044 |
Schistosoma mansoni | twik family of potassium channels-related | 0.0084 | 0.0152 | 0.0188 |
Loa Loa (eye worm) | hypothetical protein | 0.1846 | 0.8116 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.