Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0052 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0104 | 0.0104 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0309 | 1 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0162 | 0.4322 | 0.4322 |
Onchocerca volvulus | 0.0052 | 0.0104 | 0.5 | |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0052 | 0.0104 | 0.0104 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0052 | 0.0104 | 0.0104 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0052 | 0.0104 | 0.0104 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0052 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | carboxylesterase | 0.0052 | 0.0104 | 0.0104 |
Brugia malayi | hypothetical protein | 0.0095 | 0.1767 | 0.1767 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0309 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0309 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0104 | 0.0104 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0052 | 0.0104 | 0.5 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0052 | 0.0104 | 0.5 |
Onchocerca volvulus | 0.0052 | 0.0104 | 0.5 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0052 | 0.0104 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0309 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0052 | 0.0104 | 0.0104 |
Echinococcus granulosus | muscleblind protein | 0.0162 | 0.4322 | 0.4322 |
Brugia malayi | Muscleblind-like protein | 0.0162 | 0.4322 | 0.4322 |
Schistosoma mansoni | eyes absent homolog | 0.0095 | 0.1767 | 0.1767 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0104 | 0.0104 |
Brugia malayi | Carboxylesterase family protein | 0.0052 | 0.0104 | 0.0104 |
Echinococcus multilocularis | neuroligin | 0.0052 | 0.0104 | 0.0104 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0052 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.4322 | 0.4322 |
Brugia malayi | Carboxylesterase family protein | 0.0052 | 0.0104 | 0.0104 |
Onchocerca volvulus | 0.0052 | 0.0104 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1767 | 0.1767 |
Echinococcus granulosus | acetylcholinesterase | 0.0309 | 1 | 1 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0052 | 0.0104 | 0.0104 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0052 | 0.0104 | 0.0104 |
Echinococcus multilocularis | muscleblind protein | 0.0162 | 0.4322 | 0.4322 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0104 | 0.0104 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0052 | 0.0104 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0309 | 1 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0052 | 0.0104 | 0.0104 |
Echinococcus granulosus | neuroligin | 0.0052 | 0.0104 | 0.0104 |
Schistosoma mansoni | acetylcholinesterase | 0.0052 | 0.0104 | 0.0104 |
Brugia malayi | Carboxylesterase family protein | 0.0309 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0052 | 0.0104 | 0.5 |
Onchocerca volvulus | 0.0052 | 0.0104 | 0.5 | |
Loa Loa (eye worm) | carboxylesterase | 0.0052 | 0.0104 | 0.0104 |
Echinococcus multilocularis | acetylcholinesterase | 0.0309 | 1 | 1 |
Onchocerca volvulus | 0.0052 | 0.0104 | 0.5 | |
Echinococcus granulosus | carboxylesterase 5A | 0.0309 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0309 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1767 | 0.1767 |
Loa Loa (eye worm) | carboxylesterase | 0.0309 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0052 | 0.0104 | 0.0104 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0052 | 0.0104 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0052 | 0.0104 | 0.0104 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.4322 | 0.4322 |
Brugia malayi | Carboxylesterase family protein | 0.0052 | 0.0104 | 0.0104 |
Schistosoma mansoni | gliotactin | 0.0052 | 0.0104 | 0.0104 |
Echinococcus granulosus | acetylcholinesterase | 0.0309 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0052 | 0.0104 | 0.0104 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.