Detailed information for compound 1575147

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 326.433 | Formula: C20H26N2O2
  • H donors: 1 H acceptors: 1 LogP: 4.13 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: C[C@@H](Cc1ccccc1)NC(=O)Oc1cccc(c1)[C@@H](N(C)C)C
  • InChi: 1S/C20H26N2O2/c1-15(13-17-9-6-5-7-10-17)21-20(23)24-19-12-8-11-18(14-19)16(2)22(3)4/h5-12,14-16H,13H2,1-4H3,(H,21,23)/t15-,16-/m0/s1
  • InChiKey: HKJROXHSAHRDAO-HOTGVXAUSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0097 0.1332 0.15
Schistosoma mansoni hypothetical protein 0.0067 0.0177 0.0199
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0267 0.7681 1
Echinococcus multilocularis serotonin receptor 0.0299 0.8879 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0299 0.8879 1
Brugia malayi AKH receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0299 0.8879 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0299 0.8879 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0299 0.8879 1
Brugia malayi larval opioid receptor 0.0299 0.8879 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0299 0.8879 1
Brugia malayi Serotonin receptor 0.0299 0.8879 1
Loa Loa (eye worm) neuropeptide F receptor 0.0299 0.8879 1
Echinococcus granulosus g protein coupled receptor 0.0299 0.8879 1
Trypanosoma cruzi cytochrome P450, putative 0.0094 0.1214 1
Onchocerca volvulus 0.0299 0.8879 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0299 0.8879 1
Brugia malayi SWIRM domain containing protein 0.0242 0.6771 0.7626
Schistosoma mansoni neuropeptide receptor 0.0299 0.8879 1
Echinococcus granulosus neuropeptide Y receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0177 0.0199
Loa Loa (eye worm) G-protein coupled receptor 0.0299 0.8879 1
Echinococcus granulosus serotonin receptor 0.0299 0.8879 1
Leishmania major cytochrome p450-like protein 0.0094 0.1214 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0299 0.8879 1
Brugia malayi G-protein coupled receptor 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Echinococcus granulosus hypothetical protein 0.0299 0.8879 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0299 0.8879 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0299 0.8879 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0299 0.8879 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0299 0.8879 1
Schistosoma mansoni hypothetical protein 0.0166 0.3916 0.4411
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0299 0.8879 1
Echinococcus granulosus g protein coupled receptor 0.0299 0.8879 1
Loa Loa (eye worm) neuropeptide F receptor 0.0299 0.8879 1
Plasmodium vivax hypothetical protein, conserved 0.0062 0 0.5
Loa Loa (eye worm) G-protein coupled receptor 0.0299 0.8879 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0062 0 0.5
Echinococcus granulosus g protein coupled receptor 0.0299 0.8879 1
Schistosoma mansoni neuropeptide F-like receptor 0.0299 0.8879 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0094 0.1214 0.1367
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni amine GPCR 0.0299 0.8879 1
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0062 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis g protein coupled receptor 0.0299 0.8879 1
Echinococcus granulosus allatostatin A receptor 0.0299 0.8879 1
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0177 0.0199
Brugia malayi ORL1-like opioid receptor 0.0299 0.8879 1
Loa Loa (eye worm) CYP4Cod1 0.0094 0.1214 0.1367
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni biogenic amine receptor 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0299 0.8879 1
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0225 0.6121 0.6894
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Echinococcus multilocularis g protein coupled receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0299 0.8879 1
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0328 1 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Echinococcus granulosus neuropeptide Y receptor 0.0299 0.8879 1
Echinococcus granulosus neuropeptide receptor A26 0.0299 0.8879 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0097 0.1332 0.15
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0225 0.6121 0.6894
Loa Loa (eye worm) hypothetical protein 0.0225 0.6121 0.6894
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0299 0.8879 1
Brugia malayi Cytochrome P450 family protein 0.0253 0.7175 0.8081
Echinococcus granulosus dro:myosuppressin receptor 0.0299 0.8879 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Echinococcus granulosus neuropeptide receptor 0.0299 0.8879 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0097 0.1332 0.15
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi G protein-coupled receptor 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Brugia malayi Melatonin receptor type 1A 0.0299 0.8879 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0252 0.714 0.8042
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0299 0.8879 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0299 0.8879 1
Echinococcus granulosus neuropeptides capa receptor 0.0299 0.8879 1
Schistosoma mansoni amine GPCR 0.0299 0.8879 1
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0062 0 0.5
Schistosoma mansoni neuropeptide F-like receptor 0.0299 0.8879 1
Brugia malayi Dopamine receptor protein 2 0.0299 0.8879 1
Echinococcus multilocularis neuropeptide receptor 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0094 0.1214 0.1214
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0299 0.8879 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Echinococcus granulosus g-protein coupled receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi Cytochrome P450 family protein 0.0094 0.1214 0.1367
Echinococcus granulosus tachykinin peptides receptor 99D 0.0299 0.8879 1
Schistosoma mansoni hypothetical protein 0.0136 0.2764 0.3113
Echinococcus multilocularis neuropeptide s receptor 0.0299 0.8879 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0094 0.1214 0.1367
Echinococcus granulosus tm gpcr rhodopsin 0.0299 0.8879 1
Brugia malayi Dopamine receptor protein 1 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis allatostatin A receptor 0.0299 0.8879 1
Brugia malayi Serotonin receptor 0.0299 0.8879 1
Schistosoma mansoni histamine h1 receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Schistosoma mansoni neuropeptide receptor 0.0299 0.8879 1
Schistosoma mansoni hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0299 0.8879 1
Echinococcus granulosus lysine specific histone demethylase 1A 0.0225 0.6121 0.6894
Chlamydia trachomatis protoporphyrinogen oxidase 0.0062 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Brugia malayi putative neuropeptide receptor 0.0299 0.8879 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0299 0.8879 1
Echinococcus multilocularis neuropeptide Y receptor 0.0299 0.8879 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi sulfakinin receptor protein 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Brugia malayi neuropeptide F receptor 0.0299 0.8879 1
Schistosoma mansoni lipoxygenase 0.0252 0.714 0.8042
Echinococcus granulosus fmrfamide receptor 0.0299 0.8879 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0299 0.8879 1
Schistosoma mansoni hypothetical protein 0.0166 0.3916 0.4411
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0299 0.8879 1
Brugia malayi follicle stimulating hormone receptor 0.0299 0.8879 1
Echinococcus multilocularis g-protein coupled receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis neuropeptide receptor A26 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0062 0 0.5
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Trypanosoma cruzi cytochrome P450, putative 0.0094 0.1214 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0299 0.8879 1
Schistosoma mansoni neuropeptide receptor 0.0299 0.8879 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0299 0.8879 1
Brugia malayi RE15519p 0.0299 0.8879 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0299 0.8879 1
Schistosoma mansoni amine GPCR 0.0299 0.8879 1
Brugia malayi putative neuropeptide receptor NPR1 0.0299 0.8879 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0299 0.8879 1
Echinococcus multilocularis neuropeptide receptor 0.0299 0.8879 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni neuropeptide receptor 0.0299 0.8879 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0299 0.8879 1
Schistosoma mansoni hypothetical protein 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0299 0.8879 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0299 0.8879 1
Schistosoma mansoni myosin xvIII 0.0299 0.8879 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0097 0.1332 0.15
Onchocerca volvulus 0.0299 0.8879 1
Brugia malayi Cytochrome P450 family protein 0.0094 0.1214 0.1367
Plasmodium vivax hypothetical protein, conserved 0.0062 0 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0299 0.8879 1
Echinococcus multilocularis fmrfamide receptor 0.0299 0.8879 1
Echinococcus granulosus geminin 0.0166 0.3916 0.4411
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0299 0.8879 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0299 0.8879 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0299 0.8879 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0299 0.8879 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0299 0.8879 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0299 0.8879 1
Schistosoma mansoni opsin-like receptor 0.0299 0.8879 1
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0062 0 0.5
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0299 0.8879 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0299 0.8879 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0299 0.8879 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0299 0.8879 1
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0062 0 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Echinococcus granulosus somatostatin receptor 0.0299 0.8879 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Echinococcus multilocularis neuropeptide Y receptor 0.0299 0.8879 1
Plasmodium falciparum protoporphyrinogen oxidase 0.0062 0 0.5
Schistosoma mansoni biogenic amine receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis neuropeptides capa receptor 0.0299 0.8879 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0299 0.8879 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0299 0.8879 1
Echinococcus granulosus sex peptide receptor 0.0299 0.8879 1
Schistosoma mansoni hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0299 0.8879 1
Echinococcus multilocularis G protein coupled receptor 139 0.0299 0.8879 1
Echinococcus granulosus neuropeptide receptor 0.0299 0.8879 1
Schistosoma mansoni amine GPCR 0.0299 0.8879 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0299 0.8879 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0299 0.8879 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0299 0.8879 1
Brugia malayi Dopamine receptor 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0299 0.8879 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0299 0.8879 1
Brugia malayi amine oxidase, flavin-containing family protein 0.0079 0.065 0.0732
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Brugia malayi GnHR receptor homolog 0.0299 0.8879 1
Schistosoma mansoni amine GPCR 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus granulosus orexin receptor type 2 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Echinococcus multilocularis sex peptide receptor 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Echinococcus multilocularis geminin 0.0166 0.3916 0.4411
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0252 0.714 0.8042
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni adenoreceptor 0.0299 0.8879 1
Schistosoma mansoni biogenic amine receptor 0.0299 0.8879 1
Loa Loa (eye worm) TYRA-2 protein 0.0299 0.8879 1
Toxoplasma gondii histone lysine-specific demethylase 0.0062 0 0.5
Brugia malayi G-protein coupled receptor 0.0299 0.8879 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0299 0.8879 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0299 0.8879 1
Echinococcus multilocularis orexin receptor type 2 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Brugia malayi neuropeptide F receptor 0.0299 0.8879 1
Echinococcus granulosus tm gpcr rhodopsin 0.0299 0.8879 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.065 0.0732
Echinococcus granulosus rhodopsin orphan GPCR 0.0299 0.8879 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0299 0.8879 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0299 0.8879 1
Echinococcus multilocularis neuropeptides capa receptor 0.0299 0.8879 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0299 0.8879 1
Echinococcus multilocularis fmrfamide receptor 0.0299 0.8879 1
Echinococcus granulosus neuropeptide s receptor 0.0299 0.8879 1
Echinococcus multilocularis serotonin receptor 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0299 0.8879 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0299 0.8879 1
Schistosoma mansoni opsin-like receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni opsin-like receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0225 0.6121 0.6894
Brugia malayi hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni lipoxygenase 0.0176 0.4294 0.4836
Onchocerca volvulus 0.0299 0.8879 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0299 0.8879 1
Schistosoma mansoni hypothetical protein 0.0299 0.8879 1
Echinococcus granulosus neuropeptides capa receptor 0.0299 0.8879 1
Echinococcus granulosus tm gpcr rhodopsin 0.0299 0.8879 1
Trypanosoma brucei RNA helicase, putative 0.0136 0.2764 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0299 0.8879 1
Echinococcus granulosus G protein coupled receptor 139 0.0299 0.8879 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0253 0.7175 0.8081
Echinococcus multilocularis g protein coupled receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0242 0.6771 0.7626
Echinococcus multilocularis somatostatin receptor 0.0299 0.8879 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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