Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.043 | 0.043 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0352 | 0.5538 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0268 | 0.0268 |
Mycobacterium leprae | probable zinc metalloprotease | 0.0091 | 0.0831 | 0.1164 |
Mycobacterium tuberculosis | Probable zinc metalloprotease Zmp1 | 0.0091 | 0.0831 | 0.1164 |
Echinococcus granulosus | xaa pro aminopeptidase | 0.0109 | 0.1153 | 0.6684 |
Mycobacterium ulcerans | hypothetical protein | 0.0352 | 0.5538 | 1 |
Trypanosoma cruzi | aminopeptidase P1, putative | 0.0109 | 0.1153 | 1 |
Echinococcus granulosus | leucine aminopeptidase protein | 0.0118 | 0.1312 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0352 | 0.5538 | 1 |
Echinococcus multilocularis | xaa pro aminopeptidase | 0.0109 | 0.1153 | 0.6684 |
Echinococcus multilocularis | leucine aminopeptidase protein | 0.0118 | 0.1312 | 1 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0067 | 0.0401 | 0.0401 |
Leishmania major | cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 | 0.007 | 0.0446 | 0.2012 |
Loa Loa (eye worm) | peptidase family M13 containing protein | 0.0067 | 0.0401 | 0.0401 |
Mycobacterium leprae | Probable cytosol aminopeptidase PepB | 0.0118 | 0.1312 | 0.2067 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0401 | 0.0401 |
Mycobacterium ulcerans | leucyl aminopeptidase | 0.0118 | 0.1312 | 0.2067 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.043 | 0.043 |
Plasmodium falciparum | aminopeptidase P | 0.0109 | 0.1153 | 1 |
Onchocerca volvulus | 0.0065 | 0.0354 | 1 | |
Schistosoma mansoni | family M13 unassigned peptidase (M13 family) | 0.0091 | 0.0831 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0401 | 0.0401 |
Brugia malayi | metallopeptidase family M24 containing protein | 0.0109 | 0.1153 | 0.0351 |
Treponema pallidum | aminopeptidase P | 0.0109 | 0.1153 | 0.5 |
Toxoplasma gondii | creatinase domain-containing protein | 0.0109 | 0.1153 | 0.6684 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.043 | 0.043 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0352 | 0.5538 | 1 |
Wolbachia endosymbiont of Brugia malayi | leucyl aminopeptidase | 0.0118 | 0.1312 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.043 | 0.043 |
Trypanosoma cruzi | metallo-peptidase, Clan MG, Family M24, putative | 0.0109 | 0.1153 | 1 |
Toxoplasma gondii | leucyl aminopeptidase LAP | 0.0118 | 0.1312 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.043 | 0.043 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0831 | 0.0831 |
Entamoeba histolytica | aminopeptidase, putative | 0.0109 | 0.1153 | 0.0316 |
Loa Loa (eye worm) | angiotensin-converting enzyme family protein | 0.0599 | 1 | 1 |
Mycobacterium leprae | conserved hypothetical protein | 0.0352 | 0.5538 | 1 |
Mycobacterium ulcerans | zinc metalloprotease | 0.0091 | 0.0831 | 0.1164 |
Chlamydia trachomatis | cytosol aminopeptidase | 0.0118 | 0.1312 | 1 |
Mycobacterium tuberculosis | Probable aminopeptidase PepB | 0.0118 | 0.1312 | 0.2067 |
Trypanosoma brucei | Xaa-Pro aminopeptidase, putative | 0.0109 | 0.1153 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0401 | 0.0401 |
Leishmania major | aminopeptidase P1, putative,metallo-peptidase, Clan MG, Family M24 | 0.0109 | 0.1153 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.0352 | 0.5538 | 1 |
Plasmodium vivax | M17 leucyl aminopeptidase, putative | 0.0118 | 0.1312 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0831 | 0.0831 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.0401 | 0.0401 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.0831 | 0.0831 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.043 | 0.043 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.