Detailed information for compound 1587221

Basic information

Technical information
  • TDR Targets ID: 1587221
  • Name: [3-[(1S)-1-dimethylaminoethyl]phenyl] N-methy l-N-[(2R)-1-phenylpropan-2-yl]carbamate
  • MW: 340.459 | Formula: C21H28N2O2
  • H donors: 0 H acceptors: 1 LogP: 4.31 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: CN([C@H](c1cccc(c1)OC(=O)N([C@@H](Cc1ccccc1)C)C)C)C
  • InChi: 1S/C21H28N2O2/c1-16(14-18-10-7-6-8-11-18)23(5)21(24)25-20-13-9-12-19(15-20)17(2)22(3)4/h6-13,15-17H,14H2,1-5H3/t16-,17+/m1/s1
  • InChiKey: QGKSWUZOCNWHHA-SJORKVTESA-N  


Substructure search Similarity search

Network

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Synonyms

  • [3-[(1S)-1-dimethylaminoethyl]phenyl] N-methyl-N-[(1R)-1-methyl-2-phenyl-ethyl]carbamate
  • N-methyl-N-[(1R)-1-methyl-2-phenylethyl]carbamic acid [3-[(1S)-1-dimethylaminoethyl]phenyl] ester
  • N-methyl-N-[(1R)-1-methyl-2-phenyl-ethyl]carbamic acid [3-[(1S)-1-dimethylaminoethyl]phenyl] ester

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi sulfakinin receptor protein 0.0299 0.8879 1
Echinococcus multilocularis neuropeptide Y receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0299 0.8879 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0299 0.8879 1
Brugia malayi putative neuropeptide receptor 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus granulosus lysine specific histone demethylase 1A 0.0225 0.6121 0.6894
Chlamydia trachomatis protoporphyrinogen oxidase 0.0062 0 0.5
Schistosoma mansoni neuropeptide f receptor 76f 0.0299 0.8879 1
Schistosoma mansoni hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni neuropeptide receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni histamine h1 receptor 0.0299 0.8879 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Brugia malayi Serotonin receptor 0.0299 0.8879 1
Echinococcus multilocularis allatostatin A receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0094 0.1214 0.1367
Echinococcus granulosus tm gpcr rhodopsin 0.0299 0.8879 1
Brugia malayi Dopamine receptor protein 1 0.0299 0.8879 1
Echinococcus multilocularis neuropeptide s receptor 0.0299 0.8879 1
Schistosoma mansoni hypothetical protein 0.0136 0.2764 0.3113
Echinococcus granulosus tachykinin peptides receptor 99D 0.0299 0.8879 1
Brugia malayi Cytochrome P450 family protein 0.0094 0.1214 0.1367
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Echinococcus granulosus g-protein coupled receptor 0.0299 0.8879 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0299 0.8879 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0094 0.1214 0.1214
Echinococcus multilocularis neuropeptide receptor 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Brugia malayi Dopamine receptor protein 2 0.0299 0.8879 1
Schistosoma mansoni neuropeptide F-like receptor 0.0299 0.8879 1
Echinococcus granulosus neuropeptides capa receptor 0.0299 0.8879 1
Plasmodium vivax lysine-specific histone demethylase 1, putative 0.0062 0 0.5
Schistosoma mansoni amine GPCR 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0299 0.8879 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0299 0.8879 1
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0252 0.714 0.8042
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0299 0.8879 1
Brugia malayi Melatonin receptor type 1A 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi G protein-coupled receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0299 0.8879 1
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0097 0.1332 0.15
Echinococcus granulosus neuropeptide receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0299 0.8879 1
Echinococcus granulosus dro:myosuppressin receptor 0.0299 0.8879 1
Brugia malayi Cytochrome P450 family protein 0.0253 0.7175 0.8081
Loa Loa (eye worm) hypothetical protein 0.0225 0.6121 0.6894
Echinococcus multilocularis lysine specific histone demethylase 1A 0.0225 0.6121 0.6894
Brugia malayi Calcitonin receptor-like protein seb-1 0.0097 0.1332 0.15
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0299 0.8879 1
Echinococcus granulosus neuropeptide receptor A26 0.0299 0.8879 1
Echinococcus granulosus neuropeptide Y receptor 0.0299 0.8879 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Mycobacterium ulcerans flavin-containing monoamine oxidase AofH 0.0328 1 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni alpha-1 adrenergic receptor 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Echinococcus multilocularis g protein coupled receptor 0.0299 0.8879 1
Schistosoma mansoni Lysine-specific histone demethylase 1 0.0225 0.6121 0.6894
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Schistosoma mansoni biogenic amine receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi latrophilin 2 splice variant baaae 0.0067 0.0177 0.0199
Brugia malayi ORL1-like opioid receptor 0.0299 0.8879 1
Loa Loa (eye worm) CYP4Cod1 0.0094 0.1214 0.1367
Echinococcus granulosus allatostatin A receptor 0.0299 0.8879 1
Echinococcus multilocularis g protein coupled receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni amine GPCR 0.0299 0.8879 1
Mycobacterium leprae PROBABLE PROTOPORPHYRINOGEN OXIDASE HEMY (PROTOPORPHYRINOGEN-IX OXIDASE) (PROTOPORPHYRINOGENASE) (PPO) 0.0062 0 0.5
Brugia malayi hypothetical protein 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0094 0.1214 0.1367
Schistosoma mansoni neuropeptide F-like receptor 0.0299 0.8879 1
Echinococcus granulosus g protein coupled receptor 0.0299 0.8879 1
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0062 0 0.5
Loa Loa (eye worm) G-protein coupled receptor 0.0299 0.8879 1
Loa Loa (eye worm) neuropeptide F receptor 0.0299 0.8879 1
Plasmodium vivax hypothetical protein, conserved 0.0062 0 0.5
Echinococcus granulosus g protein coupled receptor 0.0299 0.8879 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0299 0.8879 1
Schistosoma mansoni hypothetical protein 0.0166 0.3916 0.4411
Echinococcus granulosus 7tm_1 domain containing protein 0.0299 0.8879 1
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0299 0.8879 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0299 0.8879 1
Echinococcus granulosus hypothetical protein 0.0299 0.8879 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi G-protein coupled receptor 0.0299 0.8879 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Leishmania major cytochrome p450-like protein 0.0094 0.1214 1
Loa Loa (eye worm) hypothetical protein 0.0067 0.0177 0.0199
Loa Loa (eye worm) G-protein coupled receptor 0.0299 0.8879 1
Echinococcus granulosus serotonin receptor 0.0299 0.8879 1
Schistosoma mansoni neuropeptide receptor 0.0299 0.8879 1
Echinococcus granulosus neuropeptide Y receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi SWIRM domain containing protein 0.0242 0.6771 0.7626
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Trypanosoma cruzi cytochrome P450, putative 0.0094 0.1214 1
Echinococcus granulosus g protein coupled receptor 0.0299 0.8879 1
Brugia malayi Serotonin receptor 0.0299 0.8879 1
Loa Loa (eye worm) neuropeptide F receptor 0.0299 0.8879 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0299 0.8879 1
Brugia malayi larval opioid receptor 0.0299 0.8879 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0299 0.8879 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Brugia malayi Tachykinin-like peptides receptor 99D 0.0299 0.8879 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0299 0.8879 1
Brugia malayi AKH receptor 0.0299 0.8879 1
Echinococcus multilocularis serotonin receptor 0.0299 0.8879 1
Schistosoma mansoni hypothetical protein 0.0067 0.0177 0.0199
Mycobacterium tuberculosis Probable flavin-containing monoamine oxidase AofH (amine oxidase) (MAO) 0.0267 0.7681 1
Loa Loa (eye worm) hypothetical protein 0.0097 0.1332 0.15
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Echinococcus multilocularis somatostatin receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0242 0.6771 0.7626
Echinococcus multilocularis g protein coupled receptor 0.0299 0.8879 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0253 0.7175 0.8081
Echinococcus granulosus G protein coupled receptor 139 0.0299 0.8879 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0299 0.8879 1
Echinococcus granulosus tm gpcr rhodopsin 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Trypanosoma brucei RNA helicase, putative 0.0136 0.2764 1
Schistosoma mansoni hypothetical protein 0.0299 0.8879 1
Echinococcus granulosus neuropeptides capa receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0299 0.8879 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0225 0.6121 0.6894
Schistosoma mansoni lipoxygenase 0.0176 0.4294 0.4836
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni opsin-like receptor 0.0299 0.8879 1
Schistosoma mansoni opsin-like receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0299 0.8879 1
Schistosoma mansoni biogenic amine (5HT) receptor 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Echinococcus multilocularis serotonin receptor 0.0299 0.8879 1
Echinococcus multilocularis fmrfamide receptor 0.0299 0.8879 1
Echinococcus granulosus neuropeptide s receptor 0.0299 0.8879 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0299 0.8879 1
Echinococcus multilocularis neuropeptides capa receptor 0.0299 0.8879 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0299 0.8879 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0079 0.065 0.0732
Echinococcus granulosus rhodopsin orphan GPCR 0.0299 0.8879 1
Echinococcus granulosus 7TM GPCR rhodopsin 0.0299 0.8879 1
Echinococcus granulosus tm gpcr rhodopsin 0.0299 0.8879 1
Brugia malayi neuropeptide F receptor 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Echinococcus multilocularis orexin receptor type 2 0.0299 0.8879 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0299 0.8879 1
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0299 0.8879 1
Schistosoma mansoni biogenic amine receptor 0.0299 0.8879 1
Loa Loa (eye worm) TYRA-2 protein 0.0299 0.8879 1
Toxoplasma gondii histone lysine-specific demethylase 0.0062 0 0.5
Brugia malayi G-protein coupled receptor 0.0299 0.8879 1
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0252 0.714 0.8042
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni adenoreceptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis geminin 0.0166 0.3916 0.4411
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Echinococcus multilocularis sex peptide receptor 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus granulosus orexin receptor type 2 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Schistosoma mansoni amine GPCR 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Brugia malayi GnHR receptor homolog 0.0299 0.8879 1
Brugia malayi amine oxidase, flavin-containing family protein 0.0079 0.065 0.0732
Echinococcus granulosus alpha 1A adrenergic receptor 0.0299 0.8879 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Brugia malayi Dopamine receptor 0.0299 0.8879 1
Echinococcus multilocularis dro:myosuppressin receptor 0.0299 0.8879 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0299 0.8879 1
Schistosoma mansoni amine GPCR 0.0299 0.8879 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0299 0.8879 1
Echinococcus granulosus neuropeptide receptor 0.0299 0.8879 1
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0299 0.8879 1
Echinococcus multilocularis G protein coupled receptor 139 0.0299 0.8879 1
Echinococcus granulosus sex peptide receptor 0.0299 0.8879 1
Schistosoma mansoni hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni biogenic amine receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Onchocerca volvulus Neuropeptide F receptor homolog 0.0299 0.8879 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0299 0.8879 1
Echinococcus multilocularis neuropeptides capa receptor 0.0299 0.8879 1
Plasmodium falciparum protoporphyrinogen oxidase 0.0062 0 0.5
Plasmodium vivax protoporphyrinogen oxidase, putative 0.0062 0 0.5
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Echinococcus multilocularis neuropeptide Y receptor 0.0299 0.8879 1
Echinococcus granulosus somatostatin receptor 0.0299 0.8879 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0299 0.8879 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0299 0.8879 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0299 0.8879 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0299 0.8879 1
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0299 0.8879 1
Schistosoma mansoni opsin-like receptor 0.0299 0.8879 1
Plasmodium falciparum lysine-specific histone demethylase 1, putative 0.0062 0 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.0299 0.8879 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0299 0.8879 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0299 0.8879 1
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0299 0.8879 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0299 0.8879 1
Echinococcus granulosus geminin 0.0166 0.3916 0.4411
Echinococcus multilocularis fmrfamide receptor 0.0299 0.8879 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0299 0.8879 1
Plasmodium vivax hypothetical protein, conserved 0.0062 0 0.5
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0097 0.1332 0.15
Schistosoma mansoni myosin xvIII 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Brugia malayi Cytochrome P450 family protein 0.0094 0.1214 0.1367
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0299 0.8879 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Schistosoma mansoni hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni neuropeptide receptor 0.0299 0.8879 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0299 0.8879 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0299 0.8879 1
Echinococcus multilocularis neuropeptide receptor 0.0299 0.8879 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Brugia malayi putative neuropeptide receptor NPR1 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0299 0.8879 1
Schistosoma mansoni amine GPCR 0.0299 0.8879 1
Brugia malayi RE15519p 0.0299 0.8879 1
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0299 0.8879 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0299 0.8879 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0299 0.8879 1
Schistosoma mansoni neuropeptide receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1
Trypanosoma cruzi cytochrome P450, putative 0.0094 0.1214 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Toxoplasma gondii histone lysine-specific demethylase LSD1/BHC110/KDMA1A 0.0062 0 0.5
Onchocerca volvulus 0.0299 0.8879 1
Echinococcus multilocularis neuropeptide receptor A26 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Echinococcus multilocularis g-protein coupled receptor 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Loa Loa (eye worm) hypothetical protein 0.0299 0.8879 1
Onchocerca volvulus 0.0299 0.8879 1
Brugia malayi follicle stimulating hormone receptor 0.0299 0.8879 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0299 0.8879 1
Schistosoma mansoni hypothetical protein 0.0166 0.3916 0.4411
Schistosoma mansoni lipoxygenase 0.0252 0.714 0.8042
Echinococcus granulosus fmrfamide receptor 0.0299 0.8879 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0299 0.8879 1
Brugia malayi neuropeptide F receptor 0.0299 0.8879 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0299 0.8879 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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