Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0424 | 0.3538 |
Echinococcus multilocularis | dnaJ subfamily B | 0.04 | 0.15 | 1 |
Brugia malayi | ERCC4 domain containing protein | 0.0039 | 0.0117 | 0.0977 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.1087 | 0.4124 | 1 |
Schistosoma mansoni | chromobox protein | 0.0011 | 0.001 | 0.0001 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.0125 | 0.07 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.0195 | 0.0452 |
Echinococcus granulosus | chromobox protein 2 | 0.0011 | 0.001 | 0.0063 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0034 | 0.0024 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.0557 | 0.2096 | 0.031 |
Plasmodium falciparum | inorganic anion exchanger, inorganic anion antiporter | 0.007 | 0.0235 | 0.5427 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.012 | 0.0268 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0034 | 0.0024 |
Echinococcus multilocularis | Chromobox protein 3 | 0.0011 | 0.001 | 0.0063 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0092 | 0.0321 | 0.19 |
Schistosoma mansoni | carbonic anhydrase | 0.012 | 0.0424 | 0.1008 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.0321 | 0.0311 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0092 | 0.0321 | 0.2675 |
Schistosoma mansoni | carbonic anhydrase-related | 0.012 | 0.0424 | 0.1008 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0062 | 0.051 |
Loa Loa (eye worm) | abnormal chemotaxis protein 14 | 0.0041 | 0.0125 | 0.1043 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0026 | 0.0172 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0322 | 0.1199 | 1 |
Echinococcus granulosus | Chromo domain | 0.0011 | 0.001 | 0.0063 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0125 | 0.0115 |
Plasmodium falciparum | DNA repair endonuclease, putative | 0.0034 | 0.0099 | 0.2146 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0154 | 0.1284 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0062 | 0.0028 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.0009 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.0125 | 0.1043 |
Plasmodium falciparum | carbonic anhydrase | 0.012 | 0.0424 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0082 | 0.0679 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.0125 | 0.0116 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0079 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 1 | 0.0011 | 0.001 | 0.0063 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0062 | 0.1247 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.0321 | 0.0311 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0322 | 0.1199 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0026 | 0.0041 |
Brugia malayi | CHD4 protein | 0.0013 | 0.0016 | 0.0133 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0113 | 0.0104 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0096 | 0.0336 | 0.2238 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0011 | 0.0091 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0075 | 0.0623 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.0321 | 0.0311 |
Loa Loa (eye worm) | helicase | 0.0011 | 0.001 | 0.0079 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0062 | 0.1247 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.012 | 0.0424 | 0.3541 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0154 | 0.1281 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0011 | 0.0088 |
Schistosoma mansoni | hypothetical protein | 0.012 | 0.0424 | 0.1008 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0026 | 0.0172 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0322 | 0.1199 | 1 |
Schistosoma mansoni | chromobox protein | 0.0011 | 0.001 | 0.0001 |
Brugia malayi | CHE-14 protein | 0.0041 | 0.0125 | 0.1046 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0142 | 0.0133 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0096 | 0.0336 | 0.2803 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0322 | 0.1199 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0081 | 0.0173 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0098 | 0.0342 | 0.0807 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0062 | 0.0028 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0026 | 0.0215 |
Loa Loa (eye worm) | CHromoDomain protein family member | 0.0013 | 0.0016 | 0.013 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0062 | 0.0028 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0026 | 0.0219 |
Echinococcus multilocularis | chromodomain helicase DNA binding protein 4 | 0.0013 | 0.0016 | 0.0104 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0322 | 0.1199 | 1 |
Schistosoma mansoni | excision repair cross-complementing 1 ercc1 | 0.0055 | 0.0178 | 0.041 |
Trypanosoma brucei | polo-like protein kinase | 0.0092 | 0.0321 | 0.2303 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0322 | 0.1199 | 0.7994 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.0321 | 0.0311 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.0228 | 0.1519 |
Trypanosoma cruzi | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.007 | 0.0235 | 0.1547 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.0602 | 0.144 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.0228 | 0.0531 |
Plasmodium vivax | DNA repair endonuclease, putative | 0.0039 | 0.0117 | 0.4765 |
Echinococcus granulosus | sterol regulatory element binding protein | 0.0041 | 0.0125 | 0.0834 |
Trypanosoma cruzi | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.007 | 0.0235 | 0.1547 |
Echinococcus granulosus | carbonic anhydrase II | 0.0322 | 0.1199 | 0.7994 |
Schistosoma mansoni | carbonic anhydrase-related | 0.012 | 0.0424 | 0.1008 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0424 | 0.3538 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.0125 | 0.0115 |
Toxoplasma gondii | ERCC4 domain-containing protein | 0.0039 | 0.0117 | 0.2586 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0011 | 0.001 | 0.0001 |
Echinococcus multilocularis | protein patched | 0.0041 | 0.0125 | 0.0834 |
Brugia malayi | SET domain containing protein | 0.0012 | 0.0012 | 0.0102 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.0533 | 0.4446 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0322 | 0.1199 | 1 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0096 | 0.0336 | 0.0793 |
Echinococcus multilocularis | chromobox protein 2 | 0.0011 | 0.001 | 0.0063 |
Brugia malayi | M-phase phosphoprotein, mpp8 | 0.0011 | 0.001 | 0.0082 |
Echinococcus multilocularis | carbonic anhydrase | 0.012 | 0.0424 | 0.2829 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.0321 | 0.0757 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 4 | 0.0013 | 0.0016 | 0.0104 |
Brugia malayi | Valyl-tRNA synthetase | 0.0011 | 0.001 | 0.0082 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0142 | 0.0133 |
Toxoplasma gondii | DNA repair protein rad10 subfamily protein | 0.0055 | 0.0178 | 0.4058 |
Brugia malayi | Heterochromatin protein 1 | 0.0068 | 0.0228 | 0.1903 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0026 | 0.0172 |
Echinococcus granulosus | dna repair endonuclease xpf | 0.0039 | 0.0117 | 0.0778 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0026 | 0.0041 |
Echinococcus granulosus | carbonic anhydrase | 0.012 | 0.0424 | 0.2829 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0034 | 0.0024 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.012 | 0.0424 | 0.3541 |
Echinococcus multilocularis | Chromo domain | 0.0011 | 0.001 | 0.0063 |
Onchocerca volvulus | 0.0012 | 0.0012 | 0.0014 | |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.0228 | 0.0219 |
Brugia malayi | hypothetical protein | 0.0148 | 0.0533 | 0.4448 |
Echinococcus granulosus | expressed conserved protein | 0.0091 | 0.0314 | 0.2089 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0095 | 0.0207 |
Brugia malayi | hypothetical protein | 0.0016 | 0.0028 | 0.0234 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.012 | 0.0268 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0012 | 0.0012 | 0.0007 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0062 | 0.2298 |
Loa Loa (eye worm) | ERCC4 domain-containing protein | 0.0039 | 0.0117 | 0.0973 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0079 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0026 | 0.0215 |
Onchocerca volvulus | 0.0439 | 0.1648 | 1 | |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 0.0228 | 0.0219 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0161 | 0.134 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 0.0228 | 0.19 |
Echinococcus multilocularis | protein dispatched 1 | 0.0047 | 0.0148 | 0.0983 |
Echinococcus multilocularis | dna repair endonuclease xpf | 0.0039 | 0.0117 | 0.0778 |
Entamoeba histolytica | DNA excision repair protein, putative | 0.0055 | 0.0178 | 0.0409 |
Loa Loa (eye worm) | helix-hairpin-helix domain-containing protein family protein | 0.0055 | 0.0178 | 0.1483 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0071 | 0.0061 |
Mycobacterium ulcerans | carbonic anhydrase | 0.1087 | 0.4124 | 0.3983 |
Schistosoma mansoni | DNA repair endonuclease xp-f / mei-9 / rad1 | 0.0039 | 0.0117 | 0.0261 |
Schistosoma mansoni | chromodomain helicase DNA binding protein | 0.0013 | 0.0016 | 0.0016 |
Brugia malayi | chromobox protein homolog 3 | 0.0038 | 0.0113 | 0.0946 |
Onchocerca volvulus | 0.0148 | 0.0533 | 0.3196 | |
Brugia malayi | Type III restriction enzyme, res subunit family protein | 0.0011 | 0.001 | 0.0082 |
Echinococcus granulosus | chromodomain helicase DNA binding protein 1 | 0.0011 | 0.001 | 0.0063 |
Leishmania major | carbonic anhydrase-like protein | 0.0322 | 0.1199 | 0.2799 |
Echinococcus granulosus | dnaJ subfamily B | 0.04 | 0.15 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.012 | 0.0424 | 0.3541 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0092 | 0.0321 | 0.2139 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0026 | 0.0041 |
Echinococcus granulosus | geminin | 0.0166 | 0.0602 | 0.4013 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0081 | 0.0537 |
Echinococcus multilocularis | expressed conserved protein | 0.0091 | 0.0314 | 0.2089 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0062 | 0.0514 |
Brugia malayi | Protein cec-1. | 0.0011 | 0.001 | 0.0082 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0011 | 0.001 | 0.0001 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0075 | 0.0159 |
Echinococcus granulosus | carbonic anhydrase | 0.012 | 0.0424 | 0.2829 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0138 | 0.0494 | 0.3294 |
Echinococcus multilocularis | carbonic anhydrase | 0.012 | 0.0424 | 0.2829 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.0228 | 0.1519 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0075 | 0.062 |
Trichomonas vaginalis | excision repair cross-complementing 1 ercc1, putative | 0.0055 | 0.0178 | 0.0168 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.001 | 0.0001 |
Toxoplasma gondii | inorganic anion transporter, sulfate permease (SulP) family protein | 0.007 | 0.0235 | 0.5427 |
Trichomonas vaginalis | nuclease Rad1 | 0.0039 | 0.0117 | 0.0107 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.0321 | 0.0311 |
Schistosoma mansoni | patched 1 | 0.0041 | 0.0125 | 0.0282 |
Schistosoma mansoni | hypothetical protein | 0.04 | 0.15 | 0.3621 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0026 | 0.0172 |
Plasmodium vivax | ERCC1 nucleotide excision repair protein, putative | 0.0055 | 0.0178 | 0.7478 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0081 | 0.0173 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.2092 | 0.7972 | 1 |
Echinococcus multilocularis | DNA excision repair protein ERCC 1 | 0.0055 | 0.0178 | 0.1185 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0079 |
Entamoeba histolytica | DNA repair endonuclease, putative | 0.0039 | 0.0117 | 0.0261 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.0424 | 0.3538 |
Schistosoma mansoni | carbonic anhydrase | 0.1087 | 0.4124 | 1 |
Leishmania major | carbonic anhydrase family protein, putative | 0.1087 | 0.4124 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0092 | 0.0321 | 0.2139 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.0321 | 0.2303 |
Toxoplasma gondii | hypothetical protein | 0.012 | 0.0424 | 1 |
Echinococcus multilocularis | carbonic anhydrase | 0.012 | 0.0424 | 0.2829 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0092 | 0.0321 | 0.0756 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.012 | 0.0268 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0034 | 0.0024 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0092 | 0.0321 | 0.0639 |
Brugia malayi | Associated with TFs and helicases family protein | 0.0011 | 0.001 | 0.0082 |
Trichomonas vaginalis | conserved hypothetical protein | 0.2622 | 1 | 1 |
Chlamydia trachomatis | sulfate transporter | 0.007 | 0.0235 | 0.5 |
Plasmodium vivax | sulfate transporter, putative | 0.007 | 0.0235 | 1 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0034 | 0.0024 |
Plasmodium falciparum | ERCC1 nucleotide excision repair protein, putative | 0.0055 | 0.0178 | 0.4058 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.0113 | 0.0632 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0027 | 0.0071 | 0.0061 |
Schistosoma mansoni | chromobox protein | 0.0068 | 0.0228 | 0.0531 |
Onchocerca volvulus | 0.0028 | 0.0075 | 0.0396 | |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.0113 | 0.0943 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0026 | 0.0172 |
Trypanosoma brucei | Sulfate transporter N-terminal domain with GLY motif/Sulfate transporter family, putative | 0.007 | 0.0235 | 0.1547 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.0602 | 0.144 |
Echinococcus granulosus | carbonic anhydrase | 0.012 | 0.0424 | 0.2829 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0026 | 0.0172 |
Giardia lamblia | Kinase, PLK | 0.0092 | 0.0321 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0154 | 0.1281 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0322 | 0.1199 | 1 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0138 | 0.0494 | 0.3294 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0095 | 0.0791 |
Schistosoma mansoni | carbonic anhydrase-related | 0.012 | 0.0424 | 0.1008 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0014 | 0.0021 | 0.0011 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0018 | 0.0034 | 0.0024 |
Loa Loa (eye worm) | hypothetical protein | 0.0096 | 0.0336 | 0.28 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0015 | 0.0023 | 0.0013 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.0321 | 0.0311 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.012 | 0.0424 | 0.3541 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0154 | 0.1284 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0092 | 0.0321 | 0.2678 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.0321 | 0.2303 |
Trichomonas vaginalis | conserved hypothetical protein | 0.2622 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0026 | 0.0041 |
Echinococcus granulosus | Chromobox protein 3 | 0.0011 | 0.001 | 0.0063 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0026 | 0.0219 |
Schistosoma mansoni | hypothetical protein | 0.004 | 0.012 | 0.0268 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0095 | 0.0788 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 0.0228 | 0.1519 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0079 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.012 | 0.0424 | 0.3538 |
Entamoeba histolytica | carbonic anhydrase, putative | 0.1087 | 0.4124 | 1 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.0009 | 0.006 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0079 |
Onchocerca volvulus | 0.003 | 0.0082 | 0.0439 | |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.1037 | 0.3936 | 0.3344 |
Echinococcus multilocularis | geminin | 0.0166 | 0.0602 | 0.4013 |
Echinococcus granulosus | DNA excision repair protein ERCC 1 | 0.0055 | 0.0178 | 0.1185 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0015 | 0.0023 | 0.0013 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0062 | 0.1247 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0322 | 0.1199 | 0.289 |
Schistosoma mansoni | chromobox protein-related (chromobox 1) (heterochromatin 1) | 0.0011 | 0.001 | 0.0001 |
Onchocerca volvulus | Putative sulfate transporter | 0.0439 | 0.1648 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.0171 | 0.3886 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0096 | 0.0336 | 0.2238 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0018 | 0.0034 | 0.0024 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.012 | 0.0424 | 0.3541 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0322 | 0.1199 | 0.289 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 0.0228 | 0.1519 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0038 | 0.0113 | 0.0104 |
Echinococcus granulosus | Protein patched homolog 1 | 0.0041 | 0.0125 | 0.0834 |
Echinococcus multilocularis | sterol regulatory element binding protein | 0.0041 | 0.0125 | 0.0834 |
Brugia malayi | Helix-hairpin-helix motif family protein | 0.0031 | 0.0087 | 0.0724 |
Schistosoma mansoni | kinase | 0.0047 | 0.0147 | 0.0334 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.0321 | 0.0311 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.001 | 0.0079 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0018 | 0.0034 | 0.0024 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0081 | 0.0537 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
Activity (functional) | = 2 % | Cytotoxicity against human HEY cells at 10 uM after 72 hrs by MTT assay | ChEMBL. | 22209417 |
Activity (functional) | = 8 % | Cytotoxicity against p53-deficient human HCT116 cells at 10 uM after 72 hrs by MTT assay | ChEMBL. | 22209417 |
Activity (functional) | = 15 % | Cytotoxicity against p53-positive human HCT116 cells at 10 uM after 72 hrs by MTT assay | ChEMBL. | 22209417 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.