Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Homo sapiens | glutamate receptor, metabotropic 1 | Starlite/ChEMBL | References |
Rattus norvegicus | Metabotropic glutamate receptor 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0284 | 0.5519 | 0.5519 | |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.012 | 0.1168 | 0.1168 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0076 | 0.0000010438 | 0.0000010438 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0082 | 0.0147 | 0.0147 |
Loa Loa (eye worm) | hypothetical protein | 0.0309 | 0.6176 | 0.6176 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0076 | 0.0000010438 | 0.0000010438 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0076 | 0.0000010438 | 0.0000010438 |
Onchocerca volvulus | Hexokinase homolog | 0.0284 | 0.5519 | 0.5519 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0000010438 | 0.0000010438 |
Schistosoma mansoni | transient receptor potential channel | 0.0076 | 0.0000010438 | 0.0000010438 |
Brugia malayi | olfactory channel protein osm-9 | 0.0076 | 0.0000010438 | 0.0000010438 |
Loa Loa (eye worm) | hexokinase | 0.0284 | 0.5519 | 0.5519 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.1797 | 0.1797 |
Brugia malayi | hexokinase type II | 0.0144 | 0.1797 | 0.1797 |
Brugia malayi | Hexokinase family protein | 0.0284 | 0.5519 | 0.5519 |
Brugia malayi | Hexokinase family protein | 0.014 | 0.1695 | 0.1695 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0098 | 0.0568 | 0.0568 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.012 | 0.1168 | 0.1168 |
Loa Loa (eye worm) | glutamate receptor | 0.0098 | 0.0568 | 0.0568 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0076 | 0.0000010438 | 0.0000010438 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0000010438 | 0.0000010438 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0089 | 0.0324 | 0.0324 |
Loa Loa (eye worm) | hypothetical protein | 0.0144 | 0.1797 | 0.1797 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0076 | 0.0000010438 | 0.0000010438 |
Schistosoma mansoni | transient receptor potential channel | 0.0076 | 0.0000010438 | 0.0000010438 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0111 | 0.0924 | 0.0924 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.1168 | 0.1168 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0082 | 0.0147 | 0.0147 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0076 | 0.0000010438 | 0.0000010438 |
Loa Loa (eye worm) | hexokinase | 0.014 | 0.1695 | 0.1695 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0000010438 | 0.0000010438 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0082 | 0.0147 | 0.0147 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.