Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Rattus norvegicus | Metabotropic glutamate receptor 1 | Starlite/ChEMBL | References |
Homo sapiens | glutamate receptor, metabotropic 1 | Starlite/ChEMBL | References |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | transient receptor potential cation channel | 0.0075 | 0.0000018619 | 0.0000018619 |
Echinococcus multilocularis | metabotropic glutamate receptor 2 | 0.0082 | 0.0324 | 0.0324 |
Schistosoma mansoni | metabotropic glutamate receptor | 0.0082 | 0.0324 | 0.0324 |
Brugia malayi | Metabotropic glutamate receptor precursor. | 0.0098 | 0.1087 | 0.1087 |
Schistosoma mansoni | transient receptor potential channel | 0.0075 | 0.0000018619 | 0.0000018619 |
Schistosoma mansoni | transient receptor potential channel | 0.0075 | 0.0000018619 | 0.0000018619 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0714 | 0.0714 |
Echinococcus multilocularis | metabotropic glutamate receptor 5 | 0.012 | 0.2173 | 0.2173 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0075 | 0.0000018619 | 0.0000018619 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0000018619 | 0.0000018619 |
Loa Loa (eye worm) | hexokinase | 0.0088 | 0.0598 | 0.0598 |
Brugia malayi | hexokinase type II | 0.009 | 0.0714 | 0.0714 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.2173 | 0.2173 |
Brugia malayi | Hexokinase family protein | 0.0178 | 0.4927 | 0.4927 |
Loa Loa (eye worm) | hexokinase | 0.0178 | 0.4927 | 0.4927 |
Echinococcus granulosus | metabotropic glutamate receptor 5 | 0.012 | 0.2173 | 0.2173 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0075 | 0.0000018619 | 0.0000018619 |
Brugia malayi | Hexokinase family protein | 0.0088 | 0.0598 | 0.0598 |
Schistosoma mansoni | metabotropic glutamate receptor 2 3 (mglur group 2) | 0.0111 | 0.1731 | 0.1731 |
Brugia malayi | metabotropic glutamate receptor subtype 5a (mGluR5a), putative | 0.0089 | 0.0645 | 0.0645 |
Loa Loa (eye worm) | hypothetical protein | 0.009 | 0.0714 | 0.0714 |
Echinococcus granulosus | metabotropic glutamate receptor 2 | 0.0082 | 0.0324 | 0.0324 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0075 | 0.0000018619 | 0.0000018619 |
Loa Loa (eye worm) | glutamate receptor | 0.0098 | 0.1087 | 0.1087 |
Onchocerca volvulus | 0.0178 | 0.4927 | 0.4927 | |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0075 | 0.0000018619 | 0.0000018619 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0000018619 | 0.0000018619 |
Brugia malayi | olfactory channel protein osm-9 | 0.0075 | 0.0000018619 | 0.0000018619 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0075 | 0.0000018619 | 0.0000018619 |
Onchocerca volvulus | Hexokinase homolog | 0.0178 | 0.4927 | 0.4927 |
Loa Loa (eye worm) | hypothetical protein | 0.0193 | 0.5672 | 0.5672 |
Loa Loa (eye worm) | hypothetical protein | 0.0075 | 0.0000018619 | 0.0000018619 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.