Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0 | 0.5 |
Brugia malayi | SWIB/MDM2 domain containing protein | 0.0066 | 0.0283 | 0.0283 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0 | 0.5 |
Loa Loa (eye worm) | brahma associated protein | 0.0066 | 0.0283 | 0.0283 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0283 | 0.0283 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0 | 0.5 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0024 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0283 | 0.0283 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0 | 0.5 |
Echinococcus granulosus | SWI:SNF matrix associated | 0.0066 | 0.0283 | 0.0283 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0024 | 0 | 0.5 |
Echinococcus multilocularis | Upstream activation factor subunit UAF30 | 0.0066 | 0.0283 | 0.0283 |
Echinococcus granulosus | tumor protein p63 | 0.1048 | 0.6785 | 0.6785 |
Plasmodium vivax | SWIB/MDM2 domain-containing protein, putative | 0.0066 | 0.0283 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.1533 | 1 | 1 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0024 | 0 | 0.5 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0024 | 0 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0 | 0.5 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0024 | 0 | 0.5 |
Onchocerca volvulus | 0.0066 | 0.0283 | 0.3286 | |
Plasmodium vivax | hypothetical protein, conserved | 0.0066 | 0.0283 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1533 | 1 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0066 | 0.0283 | 0.0283 |
Brugia malayi | brahma associated protein 60 kDa | 0.0066 | 0.0283 | 0.0283 |
Schistosoma mansoni | cellular tumor antigen P53 | 0.0153 | 0.086 | 0.086 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others, putative | 0.0024 | 0 | 0.5 |
Trypanosoma cruzi | WLM domain containing protein, putative | 0.0024 | 0 | 0.5 |
Schistosoma mansoni | brg-1 associated factor | 0.0066 | 0.0283 | 0.0283 |
Brugia malayi | brahma associated protein 60 kDa | 0.0066 | 0.0283 | 0.0283 |
Entamoeba histolytica | protein kinase, putative | 0.1533 | 1 | 0.5 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.1533 | 1 | 1 |
Loa Loa (eye worm) | SWIB/MDM2 domain-containing protein | 0.0066 | 0.0283 | 0.0283 |
Chlamydia trachomatis | SWIB complex protein | 0.0066 | 0.0283 | 0.5 |
Echinococcus multilocularis | tumor protein p63 | 0.1048 | 0.6785 | 0.6785 |
Trichomonas vaginalis | AGC family protein kinase | 0.1533 | 1 | 1 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0066 | 0.0283 | 1 |
Chlamydia trachomatis | DNA topoisomerase I | 0.0066 | 0.0283 | 0.5 |
Plasmodium falciparum | SWIB/MDM2 domain-containing protein | 0.0066 | 0.0283 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0066 | 0.0283 | 0.0283 |
Trypanosoma brucei | mitochondrial RNA binding complex 1 subunit | 0.0024 | 0 | 0.5 |
Onchocerca volvulus | 0.0153 | 0.086 | 1 | |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.0283 | 0.0283 |
Echinococcus granulosus | Upstream activation factor subunit UAF30 | 0.0066 | 0.0283 | 0.0283 |
Echinococcus granulosus | 3-phosphoinositide-dependent protein kinase 1 | 0.1533 | 1 | 1 |
Trypanosoma cruzi | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0024 | 0 | 0.5 |
Trypanosoma cruzi | mitochondrial RNA binding complex 1 subunit, putative | 0.0024 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0153 | 0.086 | 0.086 |
Toxoplasma gondii | SWIB/MDM2 domain-containing protein | 0.0066 | 0.0283 | 1 |
Echinococcus multilocularis | SWI:SNF matrix associated | 0.0066 | 0.0283 | 0.0283 |
Leishmania major | hypothetical protein, conserved | 0.0024 | 0 | 0.5 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0024 | 0 | 0.5 |
Toxoplasma gondii | DNA topoisomerase domain-containing protein | 0.0066 | 0.0283 | 1 |
Loa Loa (eye worm) | AGC/PDK1 protein kinase | 0.1533 | 1 | 1 |
Trypanosoma brucei | Zn-finger in Ran binding protein and others/FYVE zinc finger, putative | 0.0024 | 0 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.1533 | 1 | 1 |
Echinococcus multilocularis | 3 phosphoinositide dependent protein kinase 1 | 0.1533 | 1 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.1533 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.