Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.037 | 0 | 0.5 |
Trypanosoma brucei | glutaminyl cyclase, putative | 0.037 | 0 | 0.5 |
Leishmania major | glutaminyl cyclase, putative | 0.037 | 0 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.037 | 0 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.037 | 0 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.037 | 0 | 0.5 |
Trypanosoma cruzi | glutaminyl cyclase, putative | 0.037 | 0 | 0.5 |
Echinococcus granulosus | glutaminyl peptide cyclotransferase | 0.2324 | 1 | 1 |
Mycobacterium ulcerans | lipoprotein aminopeptidase LpqL | 0.037 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable lipoprotein aminopeptidase LpqL | 0.037 | 0 | 0.5 |
Echinococcus multilocularis | glutaminyl peptide cyclotransferase | 0.2324 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.037 | 0 | 0.5 |
Onchocerca volvulus | Glutaminyl cyclase homolog | 0.2324 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2324 | 1 | 1 |
Mycobacterium tuberculosis | Conserved protein | 0.037 | 0 | 0.5 |
Toxoplasma gondii | peptidase, M28 family protein | 0.037 | 0 | 0.5 |
Schistosoma mansoni | glutaminyl cyclase (M28 family) | 0.2324 | 1 | 1 |
Trypanosoma cruzi | glutaminyl cyclase, putative | 0.037 | 0 | 0.5 |
Trichomonas vaginalis | Clan MH, family M28, aminopeptidase S-like metallopeptidase | 0.037 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.037 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.