Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | ecdysteroid receptor | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0035 | 0.2557 | 0.2557 |
Onchocerca volvulus | 0.0082 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | cystatin-type cysteine proteinase inhibitor CPI-1 | 0.0082 | 1 | 1 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0035 | 0.2557 | 0.2557 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0035 | 0.2557 | 0.2557 |
Onchocerca volvulus | 0.0082 | 1 | 1 | |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0035 | 0.2557 | 0.2557 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0035 | 0.2557 | 0.2557 |
Echinococcus granulosus | proteinase inhibitor I25 cystatin | 0.0082 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | cystatin-type cysteine proteinase inhibitor CPI-2, putative | 0.0082 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0035 | 0.2557 | 0.2557 |
Onchocerca volvulus | 0.0082 | 1 | 1 | |
Schistosoma mansoni | thyroid hormone receptor | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0035 | 0.2557 | 0.2557 |
Onchocerca volvulus | 0.0082 | 1 | 1 | |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0035 | 0.2557 | 0.2557 |
Schistosoma mansoni | cystatin B | 0.0082 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0035 | 0.2557 | 0.2557 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | cystatin | 0.0082 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0035 | 0.2557 | 0.2557 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0035 | 0.2557 | 0.2557 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0035 | 0.2557 | 0.2557 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | hypothetical protein | 0.0082 | 1 | 1 |
Onchocerca volvulus | 0.0082 | 1 | 1 | |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0035 | 0.2557 | 0.2557 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | nuclear receptor NHR-88 | 0.0035 | 0.2557 | 0.2557 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0035 | 0.2557 | 0.2557 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0035 | 0.2557 | 0.2557 |
Echinococcus granulosus | Cystatin B Stefin B | 0.0082 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2557 | 0.2557 |
Schistosoma mansoni | coup transcription factor | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0035 | 0.2557 | 0.2557 |
Trichomonas vaginalis | Clan IH, family I25, phytocystatin-like peptidase inhibitor | 0.0082 | 1 | 0.5 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | cysteine protease inhibitor | 0.0082 | 1 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0035 | 0.2557 | 0.2557 |
Echinococcus multilocularis | Cystatin B (Stefin B) | 0.0082 | 1 | 1 |
Brugia malayi | cathepsin F-like cysteine proteinase | 0.0082 | 1 | 1 |
Echinococcus granulosus | FTZ F1 alpha | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0035 | 0.2557 | 0.2557 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0035 | 0.2557 | 0.2557 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0035 | 0.2557 | 0.2557 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0035 | 0.2557 | 0.2557 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0035 | 0.2557 | 0.2557 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | steroid hormone receptor | 0.0035 | 0.2557 | 0.2557 |
Echinococcus multilocularis | proteinase inhibitor I25, cystatin | 0.0082 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | cystatin | 0.0082 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0035 | 0.2557 | 0.2557 |
Schistosoma mansoni | nuclear hormone receptor | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2557 | 0.2557 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0035 | 0.2557 | 0.2557 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0035 | 0.2557 | 0.2557 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0035 | 0.2557 | 0.2557 |
Onchocerca volvulus | 0.0082 | 1 | 1 | |
Schistosoma mansoni | thyroid hormone receptor | 0.0035 | 0.2557 | 0.2557 |
Schistosoma mansoni | hypothetical protein | 0.0082 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2557 | 0.2557 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0035 | 0.2557 | 0.2557 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | nuclear hormone receptor | 0.0035 | 0.2557 | 0.2557 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0035 | 0.2557 | 0.2557 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.