Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Carboxylesterase family protein | 0.0011 | 0.0527 | 0.0527 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0011 | 0.0527 | 0.0527 |
Brugia malayi | Carboxylesterase family protein | 0.0011 | 0.0527 | 0.0527 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0011 | 0.0527 | 0.0527 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0011 | 0.0527 | 0.0527 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0066 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0011 | 0.0527 | 0.0527 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0013 | 0.0871 | 0.5 |
Onchocerca volvulus | 0.0011 | 0.0527 | 1 | |
Schistosoma mansoni | acetylcholinesterase | 0.0011 | 0.0527 | 0.0527 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 1 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0011 | 0.0527 | 0.0527 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0011 | 0.0527 | 0.0527 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0066 | 1 | 1 |
Trypanosoma brucei | cytochrome P450, putative | 0.0013 | 0.0871 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0066 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0066 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0011 | 0.0527 | 0.0527 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0066 | 1 | 1 |
Onchocerca volvulus | 0.0011 | 0.0527 | 1 | |
Echinococcus multilocularis | neuroligin | 0.0011 | 0.0527 | 0.0527 |
Onchocerca volvulus | 0.0011 | 0.0527 | 1 | |
Echinococcus granulosus | BC026374 protein S09 family | 0.0011 | 0.0527 | 0.0527 |
Echinococcus multilocularis | acetylcholinesterase | 0.0066 | 1 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0013 | 0.0871 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0066 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0527 | 0.0527 |
Schistosoma mansoni | gliotactin | 0.0011 | 0.0527 | 0.0527 |
Onchocerca volvulus | 0.0011 | 0.0527 | 1 | |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0011 | 0.0527 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0527 | 0.0527 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0013 | 0.0871 | 0.0871 |
Brugia malayi | Cytochrome P450 family protein | 0.0013 | 0.0871 | 0.0871 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0527 | 0.0527 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0013 | 0.0871 | 1 |
Brugia malayi | hypothetical protein | 0.0011 | 0.0527 | 0.0527 |
Echinococcus granulosus | neuroligin | 0.0011 | 0.0527 | 0.0527 |
Loa Loa (eye worm) | carboxylesterase | 0.0066 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0011 | 0.0527 | 0.5 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0011 | 0.0527 | 0.0527 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0011 | 0.0527 | 0.0527 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0013 | 0.0871 | 0.0871 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0013 | 0.0871 | 0.0871 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0011 | 0.0527 | 0.0527 |
Brugia malayi | Cytochrome P450 family protein | 0.0013 | 0.0871 | 0.0871 |
Onchocerca volvulus | 0.0011 | 0.0527 | 1 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0011 | 0.0527 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0527 | 0.0527 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0218 | 0.0218 |
Loa Loa (eye worm) | carboxylesterase | 0.0011 | 0.0527 | 0.0527 |
Echinococcus granulosus | acetylcholinesterase | 0.0066 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 1 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0011 | 0.0527 | 0.0527 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0011 | 0.0527 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0527 | 0.0527 |
Echinococcus granulosus | carboxylesterase 5A | 0.0066 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0527 | 0.0527 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0011 | 0.0527 | 0.0527 |
Brugia malayi | Carboxylesterase family protein | 0.0011 | 0.0527 | 0.0527 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0011 | 0.0527 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0527 | 0.0527 |
Leishmania major | cytochrome p450-like protein | 0.0013 | 0.0871 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.