Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0139 | 0.9346 | 0.9162 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | voltage gated hydrogen channel 1 | 0.0063 | 0.2196 | 0.2005 |
Leishmania major | hypothetical protein, conserved | 0.0063 | 0.2196 | 0.5 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0063 | 0.2196 | 0.2005 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0067 | 0.2641 | 0.057 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0063 | 0.2196 | 0.2005 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0063 | 0.2196 | 1 |
Echinococcus multilocularis | transient receptor potential cation channel | 0.0067 | 0.2641 | 0.057 |
Echinococcus granulosus | potassium voltage gated channel subfamily C | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | calcium activated potassium channel | 0.0063 | 0.2196 | 0.2005 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0063 | 0.2196 | 1 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel alpha 1 | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | TRP transient receptor potential channel | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | two pore calcium channel protein 2 | 0.0063 | 0.2196 | 0.2005 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0063 | 0.2196 | 0.5 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.0335 | 0.5 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0063 | 0.2196 | 0.2005 |
Leishmania major | hypothetical protein, unknown function | 0.0063 | 0.2196 | 0.5 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0146 | 1 | 1 |
Echinococcus granulosus | voltage dependent calcium channel type d subunit|voltage dependent calcium channel|voltage dependent L type calcium channel subu | 0.0063 | 0.2196 | 0.2005 |
Onchocerca volvulus | 0.0063 | 0.2196 | 0.5 | |
Echinococcus granulosus | shaker cognate | 0.0063 | 0.2196 | 0.2005 |
Leishmania major | calcium channel protein, putative,ion transporter, putative | 0.0063 | 0.2196 | 0.5 |
Echinococcus granulosus | potassium large conductance calcium activated | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | cyclic nucleotide gated cation channel | 0.0063 | 0.2196 | 0.2005 |
Brugia malayi | olfactory channel protein osm-9 | 0.0067 | 0.2641 | 0.057 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0063 | 0.2196 | 0.2005 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0063 | 0.2196 | 1 |
Echinococcus granulosus | cyclic nucleotide gated cation channel alpha 3 | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0063 | 0.2196 | 0.2005 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0039 | 0 | 0.5 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0067 | 0.2641 | 0.2484 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0063 | 0.2196 | 0.2005 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0146 | 1 | 1 |
Trypanosoma cruzi | Voltage-dependent calcium channel subunit, putative | 0.0063 | 0.2196 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0067 | 0.2641 | 0.057 |
Echinococcus granulosus | two pore calcium channel protein 1 | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0142 | 0.9616 | 1 |
Echinococcus granulosus | sodium channel protein | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | voltage gated potassium channel | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | potassium voltage gated channel subfamily H | 0.0063 | 0.2196 | 0.2005 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0067 | 0.2641 | 0.057 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0063 | 0.2196 | 1 |
Echinococcus granulosus | sodium leak channel non selective protein | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | potassium voltage gated channel subfamily A | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.0063 | 0.2196 | 0.2005 |
Trypanosoma brucei | RNA helicase, putative | 0.0139 | 0.9346 | 1 |
Echinococcus granulosus | voltage gated potassium channel | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | potassium channel KvQLT family member kqt 1 | 0.0063 | 0.2196 | 0.2005 |
Loa Loa (eye worm) | acetyltransferase | 0.0146 | 1 | 1 |
Echinococcus granulosus | Potassium voltage gated channel protein Shaw | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | voltage dependent L type calcium channel subunit|voltage dependent calcium channel | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | ryanodine receptor 44f | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0063 | 0.2196 | 0.2005 |
Onchocerca volvulus | Transient receptor potential cation channel trpm homolog | 0.0063 | 0.2196 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0063 | 0.2196 | 1 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0 | 0.5 |
Echinococcus granulosus | potassium voltage gated channel subfamily D | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | voltage dependent calcium channel | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | hypothetical protein | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0063 | 0.2196 | 0.2005 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0039 | 0 | 0.5 |
Echinococcus granulosus | voltage gated sodium channel Nav1 alpha subunit | 0.0063 | 0.2196 | 0.2005 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0067 | 0.2641 | 0.2484 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0063 | 0.2196 | 1 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0063 | 0.2196 | 0.2005 |
Toxoplasma gondii | transporter, cation channel family protein | 0.0063 | 0.2196 | 1 |
Schistosoma mansoni | transient receptor potential channel | 0.0067 | 0.2641 | 0.057 |
Echinococcus granulosus | potassium voltage gated channel protein | 0.0063 | 0.2196 | 0.2005 |
Toxoplasma gondii | hypothetical protein | 0.0063 | 0.2196 | 1 |
Trypanosoma cruzi | inositol 1,4,5-trisphosphate receptor, putative | 0.0063 | 0.2196 | 0.5 |
Echinococcus granulosus | transient receptor potential cation channel | 0.0063 | 0.2196 | 0.2005 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0063 | 0.2196 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.