Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | cathepsin l1 | 0.0459 | 0.1329 | 0.1329 |
Echinococcus granulosus | cathepsin b | 0.1104 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.067 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.067 | 0.4176 | 0.4176 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.067 | 0.4176 | 0.4176 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.067 | 0.4176 | 0.3437 |
Entamoeba histolytica | cysteine proteinase, putative | 0.067 | 0.4176 | 1 |
Plasmodium vivax | vivapain-2 | 0.067 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Onchocerca volvulus | 0.067 | 0.4176 | 1 | |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.067 | 0.4176 | 0.4176 |
Leishmania major | cathepsin L-like protease | 0.067 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.067 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.067 | 0.4176 | 1 |
Onchocerca volvulus | 0.067 | 0.4176 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.067 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.0459 | 0.1329 | 0.1329 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.067 | 0.4176 | 0.4176 |
Loa Loa (eye worm) | ctsf protein | 0.067 | 0.4176 | 0.3437 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.067 | 0.4176 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0443 | 0.1126 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0459 | 0.1329 | 0.0228 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.067 | 0.4176 | 0.3437 |
Toxoplasma gondii | cathepsin CPL | 0.067 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0459 | 0.1329 | 0.0228 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Brugia malayi | Papain family cysteine protease containing protein | 0.067 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.067 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.067 | 0.4176 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.067 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.067 | 0.4176 | 0.4176 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.067 | 0.4176 | 0.4176 |
Onchocerca volvulus | Cathepsin F homolog | 0.067 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.067 | 0.4176 | 0.4176 |
Leishmania major | cathepsin L-like protease | 0.067 | 0.4176 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.067 | 0.4176 | 1 |
Leishmania major | cathepsin L-like protease | 0.067 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0459 | 0.1329 | 0.0228 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.067 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.067 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0459 | 0.1329 | 0.3182 |
Leishmania major | cathepsin L-like protease | 0.067 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0459 | 0.1329 | 0.1329 |
Onchocerca volvulus | Cathepsin L homolog | 0.067 | 0.4176 | 1 |
Onchocerca volvulus | 0.067 | 0.4176 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.067 | 0.4176 | 0.3437 |
Giardia lamblia | Cathepsin B precursor | 0.0443 | 0.1126 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.067 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0443 | 0.1126 | 0.2697 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.067 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0443 | 0.1126 | 0.2697 |
Brugia malayi | Cathepsin L-like precursor | 0.067 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.067 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.067 | 0.4176 | 1 |
Plasmodium vivax | vivapain-2 | 0.067 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.067 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.0459 | 0.1329 | 0.1329 |
Loa Loa (eye worm) | fibroinase | 0.067 | 0.4176 | 0.3437 |
Loa Loa (eye worm) | hypothetical protein | 0.1104 | 1 | 1 |
Onchocerca volvulus | 0.067 | 0.4176 | 1 | |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0459 | 0.1329 | 0.1329 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.067 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 0.4176 | 0.3437 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.067 | 0.4176 | 1 |
Onchocerca volvulus | 0.067 | 0.4176 | 1 | |
Trypanosoma cruzi | cysteine peptidase, putative | 0.067 | 0.4176 | 0.4176 |
Brugia malayi | Cathepsin L-like precursor | 0.0459 | 0.1329 | 0.1329 |
Brugia malayi | Cathepsin L-like precursor | 0.067 | 0.4176 | 0.4176 |
Leishmania major | cathepsin L-like protease | 0.067 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0459 | 0.1329 | 0.3182 |
Echinococcus multilocularis | cysteine protease | 0.067 | 0.4176 | 0.4176 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0443 | 0.1126 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.067 | 0.4176 | 0.4176 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.067 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.067 | 0.4176 | 0.4176 |
Leishmania major | cathepsin L-like protease | 0.067 | 0.4176 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.1104 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1104 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.1104 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.067 | 0.4176 | 0.4176 |
Echinococcus multilocularis | cathepsin b | 0.1104 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0459 | 0.1329 | 0.3182 |
Echinococcus multilocularis | cathepsin b | 0.1104 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.067 | 0.4176 | 0.4176 |
Onchocerca volvulus | 0.067 | 0.4176 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.067 | 0.4176 | 1 |
Echinococcus multilocularis | cysteine protease | 0.067 | 0.4176 | 0.4176 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0459 | 0.1329 | 0.1329 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.067 | 0.4176 | 0.4176 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0443 | 0.1126 | 0.1126 |
Leishmania major | cysteine peptidase A (CPA) | 0.067 | 0.4176 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.067 | 0.4176 | 0.4176 |
Entamoeba histolytica | cysteine protease, putative | 0.067 | 0.4176 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0443 | 0.1126 | 0.1126 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1104 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.067 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1104 | 1 | 1 |
Onchocerca volvulus | 0.067 | 0.4176 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.067 | 0.4176 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1104 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.067 | 0.4176 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.