Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0369 | 0.3501 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0917 | 0.2619 |
Schistosoma mansoni | CD36-like class B scavenger receptor | 0.0369 | 0.3501 | 1 |
Schistosoma mansoni | CD36-like class B scavenger receptor | 0.0369 | 0.3501 | 1 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0201 | 0.1604 | 0.1604 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0917 | 0.2619 |
Echinococcus multilocularis | CD36 class B scavenger receptor | 0.0369 | 0.3501 | 0.3501 |
Onchocerca volvulus | Lysosome membrane protein 2 homolog | 0.0369 | 0.3501 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0185 | 0.1423 | 0.4065 |
Echinococcus granulosus | CD36 class B scavenger receptor | 0.0369 | 0.3501 | 1 |
Schistosoma mansoni | cd36 antigen | 0.0139 | 0.0917 | 0.2619 |
Brugia malayi | CD36 family protein | 0.0369 | 0.3501 | 1 |
Echinococcus multilocularis | lysosome membrane protein 2 | 0.0369 | 0.3501 | 0.3501 |
Echinococcus multilocularis | CD36 class B scavenger receptor | 0.0369 | 0.3501 | 0.3501 |
Loa Loa (eye worm) | hypothetical protein | 0.0139 | 0.0917 | 0.2619 |
Echinococcus granulosus | lysosome membrane protein 2 | 0.0369 | 0.3501 | 1 |
Schistosoma mansoni | scavenger receptor class B type-2 (sr-B2) | 0.0369 | 0.3501 | 1 |
Echinococcus granulosus | CD36 class B scavenger receptor | 0.0369 | 0.3501 | 1 |
Echinococcus multilocularis | CD36 class B scavenger receptor | 0.0369 | 0.3501 | 0.3501 |
Echinococcus granulosus | CD36 class B scavenger receptor | 0.0369 | 0.3501 | 1 |
Echinococcus granulosus | CD36 class B scavenger receptor | 0.0369 | 0.3501 | 1 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0201 | 0.1604 | 0.4581 |
Brugia malayi | hypothetical protein | 0.0139 | 0.0917 | 0.2619 |
Echinococcus multilocularis | geminin | 0.0185 | 0.1423 | 0.1423 |
Echinococcus granulosus | CD36 class B scavenger receptor | 0.0369 | 0.3501 | 1 |
Echinococcus multilocularis | CD36 class B scavenger receptor | 0.0369 | 0.3501 | 0.3501 |
Loa Loa (eye worm) | hypothetical protein | 0.0369 | 0.3501 | 1 |
Echinococcus granulosus | geminin | 0.0185 | 0.1423 | 0.4065 |
Brugia malayi | hypothetical protein | 0.0139 | 0.0917 | 0.2619 |
Schistosoma mansoni | hypothetical protein | 0.0309 | 0.2828 | 0.8077 |
Loa Loa (eye worm) | hypothetical protein | 0.0369 | 0.3501 | 1 |
Echinococcus multilocularis | CD36 class B scavenger receptor | 0.0369 | 0.3501 | 0.3501 |
Schistosoma mansoni | hypothetical protein | 0.0185 | 0.1423 | 0.4065 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | > 32 ug ml-1 | Antibacterial activity against Escherichia coli isolate EC155 expressing tetA gene | ChEMBL. | 22148555 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.