Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | chromobox protein 2 | 0.0201 | 0.1996 | 0.3253 |
Echinococcus granulosus | tumor suppressor p53 binding protein 1 | 0.0335 | 0.3573 | 0.5962 |
Echinococcus multilocularis | histone acetyltransferase MYST2 | 0.0098 | 0.0769 | 0.1147 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0095 | 0.0735 | 0.064 |
Schistosoma mansoni | chromobox protein | 0.0201 | 0.1996 | 0.1914 |
Toxoplasma gondii | PLU-1 family protein | 0.0045 | 0.014 | 1 |
Loa Loa (eye worm) | mbt repeat family protein | 0.0283 | 0.2959 | 0.5001 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0079 | 0.0547 | 0.0766 |
Echinococcus granulosus | suppression of tumorigenicity 18 protein | 0.0098 | 0.0769 | 0.1147 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0272 | 0.2828 | 0.2754 |
Echinococcus multilocularis | SAM and MBT domain containing protein | 0.0393 | 0.4271 | 0.7161 |
Echinococcus granulosus | histone acetyltransferase MYST2 | 0.0098 | 0.0769 | 0.1147 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0095 | 0.0735 | 0.1089 |
Echinococcus granulosus | polycomb protein SCMH1 | 0.0272 | 0.2828 | 0.4682 |
Echinococcus multilocularis | suppression of tumorigenicity 18 protein | 0.0098 | 0.0769 | 0.1147 |
Echinococcus multilocularis | polycomb protein SCMH1 | 0.0272 | 0.2828 | 0.4682 |
Schistosoma mansoni | sex comb on midleg homolog | 0.0272 | 0.2828 | 0.2754 |
Echinococcus multilocularis | tumor suppressor p53 binding protein 1 | 0.0335 | 0.3573 | 0.5962 |
Brugia malayi | mbt repeat family protein | 0.0283 | 0.2959 | 0.5001 |
Echinococcus granulosus | SAM and MBT domain containing protein | 0.0393 | 0.4271 | 0.7161 |
Loa Loa (eye worm) | hypothetical protein | 0.0467 | 0.5147 | 1 |
Echinococcus granulosus | endonuclease exonuclease phosphatase | 0.0533 | 0.5924 | 1 |
Schistosoma mansoni | scm-relatedprotein containing 4 mbt domains (sfmbt) | 0.0393 | 0.4271 | 0.4212 |
Schistosoma mansoni | myelin transcription factor 1 myt1 | 0.0098 | 0.0769 | 0.0674 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.014 | 0.1268 | 0.1139 |
Brugia malayi | jmjC domain containing protein | 0.014 | 0.1268 | 0.1139 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0117 | 0.0991 | 0.1527 |
Brugia malayi | mbt repeat family protein | 0.0467 | 0.5147 | 1 |
Echinococcus multilocularis | endonuclease exonuclease phosphatase | 0.0533 | 0.5924 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0095 | 0.0735 | 0.064 |
Echinococcus multilocularis | chromobox protein 2 | 0.0201 | 0.1996 | 0.3253 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0117 | 0.0991 | 0.1527 |
Schistosoma mansoni | hypothetical protein | 0.0335 | 0.3573 | 0.3507 |
Onchocerca volvulus | Polycomb protein Sfmbt homolog | 0.0467 | 0.5147 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.