Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0062 | 0.29 | 0.2808 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1029 | 0.2024 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0091 | 0.4872 | 0.4806 |
Echinococcus granulosus | TRP transient receptor potential channel | 0.0035 | 0.1029 | 0.0914 |
Loa Loa (eye worm) | hypothetical protein | 0.0059 | 0.2685 | 0.5277 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0127 | 0.0127 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0814 | 0.16 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.3334 | 0.6554 |
Brugia malayi | Bromodomain containing protein | 0.0037 | 0.1176 | 0.2673 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0062 | 0.29 | 0.2808 |
Schistosoma mansoni | transient receptor potential channel | 0.0062 | 0.29 | 0.29 |
Brugia malayi | Transient-receptor-potential like protein | 0.0035 | 0.1029 | 0.2234 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0094 | 0.5087 | 0.5087 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.1181 | 0.2321 |
Schistosoma mansoni | transient receptor potential channel | 0.0062 | 0.29 | 0.29 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.1018 | 0.0903 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0091 | 0.4872 | 0.4806 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0062 | 0.29 | 0.2808 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0062 | 0.29 | 0.2808 |
Echinococcus multilocularis | geminin | 0.0166 | 1 | 1 |
Schistosoma mansoni | transient receptor potential channel | 0.0094 | 0.5087 | 0.5087 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0094 | 0.5087 | 0.5024 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.5087 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.1338 | 0.263 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 1 | 1 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.2601 | 0.2505 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.2601 | 0.2505 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.1018 | 0.0903 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 1 | 1 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.0035 | 0.1029 | 0.0914 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1465 | 0.288 |
Brugia malayi | Bromodomain containing protein | 0.0073 | 0.3619 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0062 | 0.2839 | 0.2839 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0094 | 0.5087 | 0.5024 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.