Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | aminopeptidase N | 0.0521 | 1 | 1 |
Schistosoma mansoni | family M1 non-peptidase homologue (M01 family) | 0.0099 | 0.13 | 0.5387 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.13 | 0.1463 |
Loa Loa (eye worm) | TATA binding protein associated factor | 0.0054 | 0.036 | 0.0405 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0153 | 0.2413 | 1 |
Leishmania major | aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 | 0.0153 | 0.2413 | 1 |
Trypanosoma brucei | Aminopeptidase M1, putative | 0.0153 | 0.2413 | 1 |
Loa Loa (eye worm) | leukotriene A4 hydrolase | 0.0054 | 0.036 | 0.0405 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.036 | 0.0405 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0153 | 0.2413 | 0.2129 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.0348 | 0.0348 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.0348 | 0.0392 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0153 | 0.2413 | 0.2129 |
Echinococcus multilocularis | aminopeptidase N | 0.0521 | 1 | 1 |
Trypanosoma cruzi | metallo-peptidase, Clan MA(E) Family M1 | 0.0099 | 0.13 | 0.4578 |
Brugia malayi | hypothetical protein | 0.0054 | 0.036 | 0.036 |
Schistosoma mansoni | cytosol alanyl aminopeptidase (M01 family) | 0.0153 | 0.2413 | 1 |
Leishmania major | aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 | 0.0153 | 0.2413 | 1 |
Brugia malayi | TATA binding protein associated factor | 0.0054 | 0.036 | 0.036 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0153 | 0.2413 | 0.2129 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.13 | 0.1463 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0099 | 0.13 | 0.0975 |
Brugia malayi | Peptidase family M1 containing protein | 0.0054 | 0.036 | 0.036 |
Loa Loa (eye worm) | peptidase family M1 containing protein | 0.0421 | 0.7948 | 0.8943 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0153 | 0.2413 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.0348 | 0.0348 |
Schistosoma mansoni | Tata binding protein associated factor (M01 family) | 0.0054 | 0.036 | 0.1493 |
Trypanosoma cruzi | aminopeptidase, putative | 0.0153 | 0.2413 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.036 | 0.0405 |
Loa Loa (eye worm) | aminopeptidase N | 0.0153 | 0.2413 | 0.2715 |
Toxoplasma gondii | aminopeptidase n, putative | 0.0054 | 0.036 | 0.5 |
Mycobacterium ulcerans | aminopeptidase N PepN | 0.0153 | 0.2413 | 1 |
Trichomonas vaginalis | Clan MA, family M1, aminopeptidase N-like metallopeptidase | 0.0153 | 0.2413 | 1 |
Schistosoma mansoni | leukotriene A4 hydrolase (M01 family) | 0.0054 | 0.036 | 0.1493 |
Onchocerca volvulus | 0.0153 | 0.2413 | 0.2129 | |
Onchocerca volvulus | 0.0521 | 1 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0467 | 0.8887 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0367 | 0.6835 | 0.7691 |
Plasmodium falciparum | M1-family alanyl aminopeptidase, putative | 0.0054 | 0.036 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.0348 | 0.0392 |
Trypanosoma brucei | metallo-peptidase, Clan MA(E) Family M1 | 0.0153 | 0.2413 | 1 |
Toxoplasma gondii | aminopeptidase N protein | 0.0054 | 0.036 | 0.5 |
Brugia malayi | Peptidase family M1 containing protein | 0.0153 | 0.2413 | 0.2413 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0153 | 0.2413 | 0.2129 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0153 | 0.2413 | 1 |
Trypanosoma cruzi | metallo-peptidase, clan MA(E), family M1, putative | 0.0153 | 0.2413 | 1 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0054 | 0.036 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0153 | 0.2413 | 0.2129 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0153 | 0.2413 | 0.2129 |
Plasmodium vivax | M1-family alanyl aminopeptidase, putative | 0.0054 | 0.036 | 0.5 |
Trypanosoma cruzi | Aminopeptidase M1, putative | 0.0153 | 0.2413 | 1 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0153 | 0.2413 | 0.2129 |
Entamoeba histolytica | aminopeptidase, putative | 0.0153 | 0.2413 | 0.5 |
Schistosoma mansoni | aminopeptidase A (M01 family) | 0.0054 | 0.036 | 0.1493 |
Echinococcus granulosus | puromycin sensitive aminopeptidase | 0.0153 | 0.2413 | 0.2129 |
Brugia malayi | hypothetical protein | 0.0153 | 0.2413 | 0.2413 |
Plasmodium falciparum | M1-family alanyl aminopeptidase | 0.0054 | 0.036 | 0.5 |
Echinococcus multilocularis | puromycin sensitive aminopeptidase | 0.0153 | 0.2413 | 0.2129 |
Toxoplasma gondii | aminopeptidase N, putative | 0.0054 | 0.036 | 0.5 |
Echinococcus multilocularis | Peptidase M1, membrane alanine aminopeptidase, N terminal | 0.0153 | 0.2413 | 0.2129 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.036 | 0.0405 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.