Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | protein kinase | 0.038 | 0.0671 | 0.0153 |
Echinococcus granulosus | 3'partial|serine:threonine protein kinase PAK 2 | 0.0373 | 0.0526 | 0.0526 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0479 | 0.2627 | 0.2218 |
Loa Loa (eye worm) | STE/STE20/PAKA protein kinase | 0.0479 | 0.2627 | 0.2252 |
Loa Loa (eye worm) | hypothetical protein | 0.0845 | 0.9855 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0852 | 1 | 1 |
Echinococcus granulosus | neural Wiskott Aldrich syndrome protein | 0.0373 | 0.0526 | 0.0526 |
Echinococcus multilocularis | PAK box P21 Rho binding | 0.038 | 0.0671 | 0.0671 |
Giardia lamblia | Kinase, STE STE20 | 0.0852 | 1 | 0.5 |
Trypanosoma cruzi | p21-activated kinase 3, putative | 0.0479 | 0.2627 | 1 |
Schistosoma mansoni | protein kinase | 0.0852 | 1 | 1 |
Loa Loa (eye worm) | STE/STE20/PAKB protein kinase | 0.0719 | 0.7373 | 0.734 |
Echinococcus granulosus | PAK box P21 Rho binding | 0.0373 | 0.0526 | 0.0526 |
Entamoeba histolytica | p21-activated kinase | 0.0852 | 1 | 1 |
Trichomonas vaginalis | STE family protein kinase | 0.0852 | 1 | 1 |
Toxoplasma gondii | prolyl endopeptidase | 0.044 | 0.1841 | 0.5 |
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.044 | 0.1841 | 0.5 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.044 | 0.1841 | 0.1389 |
Echinococcus multilocularis | neural Wiskott Aldrich syndrome protein | 0.0373 | 0.0526 | 0.0526 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.044 | 0.1841 | 0.1389 |
Echinococcus multilocularis | prolyl endopeptidase | 0.044 | 0.1841 | 0.1841 |
Echinococcus multilocularis | PAK box P21 Rho binding | 0.0373 | 0.0526 | 0.0526 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0845 | 0.9855 | 0.9844 |
Brugia malayi | p21/Cdc42/Rac1-activated kinase | 0.0479 | 0.2627 | 0.2218 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0852 | 1 | 1 |
Brugia malayi | serine/threonine-protein kinase PAK 7 | 0.0719 | 0.7373 | 0.7227 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0479 | 0.2627 | 0.2218 |
Trichomonas vaginalis | STE family protein kinase | 0.0852 | 1 | 1 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.044 | 0.1841 | 0.5 |
Echinococcus multilocularis | serine:threonine protein kinase PAK 3 | 0.0852 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.038 | 0.0671 | 0.0153 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0394 | 0.093 | 0.5 |
Trichomonas vaginalis | STE family protein kinase | 0.0852 | 1 | 1 |
Trypanosoma cruzi | STE/STE20 serine/threonine-protein kinase, putative | 0.0479 | 0.2627 | 1 |
Loa Loa (eye worm) | STE/STE20/PAKA protein kinase | 0.0479 | 0.2627 | 0.2252 |
Entamoeba histolytica | protein kinase, putative | 0.0852 | 1 | 1 |
Echinococcus multilocularis | p21 activated protein kinase 1 Dpak1 | 0.0852 | 1 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PAK 1 | 0.0472 | 0.2482 | 0.2482 |
Entamoeba histolytica | protein kinase, putative | 0.038 | 0.0671 | 0.0153 |
Schistosoma mansoni | protein kinase | 0.0852 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.044 | 0.1841 | 0.141 |
Brugia malayi | prolyl oligopeptidase family protein | 0.044 | 0.1841 | 0.1389 |
Echinococcus granulosus | serine:threonine protein kinase PAK 3 | 0.0852 | 1 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.038 | 0.0671 | 0.0153 |
Trichomonas vaginalis | mitogen-activated protein kinase kinase kinase 3, MAPKKK3, MEKK3, putative | 0.0479 | 0.2627 | 0.2097 |
Trichomonas vaginalis | STE family protein kinase | 0.0852 | 1 | 1 |
Trypanosoma brucei | prolyl endopeptidase | 0.044 | 0.1841 | 0.5 |
Echinococcus granulosus | p21 activated protein kinase 1 Dpak1 | 0.0852 | 1 | 1 |
Echinococcus granulosus | prolyl endopeptidase | 0.044 | 0.1841 | 0.1841 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.