Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0006 | 0.0013 |
Toxoplasma gondii | hypothetical protein | 0.1043 | 0.1811 | 0.5 |
Echinococcus granulosus | muscleblind protein | 0.0159 | 0.0262 | 0.0596 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.1043 | 0.1811 | 0.4122 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.3241 | 0.5668 | 1 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0159 | 0.0262 | 0.0596 |
Loa Loa (eye worm) | hypothetical protein | 0.1043 | 0.1811 | 0.4122 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1043 | 0.1811 | 0.1811 |
Leishmania major | carbonic anhydrase family protein, putative | 0.5711 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.1043 | 0.1811 | 0.1811 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.001 | 0.0023 |
Schistosoma mansoni | carbonic anhydrase | 0.5711 | 1 | 1 |
Echinococcus granulosus | roundabout 2 | 0.0016 | 0.001 | 0.0023 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.5711 | 1 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0068 | 0.0154 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.2514 | 0.4393 | 0.4393 |
Echinococcus granulosus | carbonic anhydrase | 0.1043 | 0.1811 | 0.4122 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.2514 | 0.4393 | 0.5 |
Echinococcus multilocularis | carbonic anhydrase II | 0.2514 | 0.4393 | 1 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.2514 | 0.4393 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0068 | 0.0154 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0049 | 0.0068 | 0.0154 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.2514 | 0.4393 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.1043 | 0.1811 | 0.4122 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0049 | 0.0068 | 0.0154 |
Trichomonas vaginalis | conserved hypothetical protein | 0.247 | 0.4314 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.0262 | 0.0596 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0049 | 0.0068 | 0.0154 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1043 | 0.1811 | 0.4122 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0153 | 0.0251 | 1 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1043 | 0.1811 | 0.1811 |
Echinococcus granulosus | carbonic anhydrase | 0.1043 | 0.1811 | 0.4122 |
Trichomonas vaginalis | conserved hypothetical protein | 0.247 | 0.4314 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1043 | 0.1811 | 0.4122 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.2514 | 0.4393 | 1 |
Echinococcus granulosus | carbonic anhydrase | 0.1043 | 0.1811 | 0.4122 |
Brugia malayi | Muscleblind-like protein | 0.0159 | 0.0262 | 0.0596 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.2514 | 0.4393 | 0.4393 |
Echinococcus multilocularis | carbonic anhydrase | 0.1043 | 0.1811 | 0.4122 |
Echinococcus multilocularis | muscleblind protein | 0.0159 | 0.0262 | 0.0596 |
Echinococcus multilocularis | neuroglian | 0.0013 | 0.0005 | 0.001 |
Echinococcus granulosus | neuroglian | 0.0013 | 0.0005 | 0.001 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0164 | 0.027 | 0.0615 |
Echinococcus multilocularis | carbonic anhydrase | 0.1043 | 0.1811 | 0.4122 |
Echinococcus multilocularis | carbonic anhydrase | 0.1043 | 0.1811 | 0.4122 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1043 | 0.1811 | 0.4122 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0013 | 0.0006 | 0.0013 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0049 | 0.0068 | 0.0154 |
Schistosoma mansoni | carbonic anhydrase | 0.1043 | 0.1811 | 0.1811 |
Plasmodium falciparum | carbonic anhydrase | 0.1043 | 0.1811 | 0.5 |
Mycobacterium ulcerans | carbonic anhydrase | 0.5711 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0068 | 0.0068 |
Echinococcus granulosus | carbonic anhydrase II | 0.2514 | 0.4393 | 1 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0164 | 0.027 | 0.0615 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0068 | 0.0068 |
Schistosoma mansoni | cell adhesion molecule | 0.0013 | 0.0006 | 0.0006 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.001 | 0.0023 |
Echinococcus granulosus | twitchin | 0.0013 | 0.0005 | 0.001 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.2514 | 0.4393 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1043 | 0.1811 | 0.4122 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.2514 | 0.4393 | 0.5 |
Schistosoma mansoni | nephrin | 0.0013 | 0.0005 | 0.0005 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1043 | 0.1811 | 0.4122 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.1043 | 0.1811 | 0.4122 |
Echinococcus multilocularis | roundabout 2 | 0.0016 | 0.001 | 0.0023 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.2514 | 0.4393 | 1 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1043 | 0.1811 | 0.1811 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0049 | 0.0068 | 0.0068 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.0262 | 0.0596 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.