Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0157 | 0.0399 | 0.0399 |
Brugia malayi | Protein kinase domain containing protein | 0.0465 | 0.1669 | 0.1669 |
Entamoeba histolytica | hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0157 | 0.0399 | 0.0166 |
Trypanosoma cruzi | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 0.5 |
Schistosoma mansoni | nicotinate phosphoribosyltransferase related pre-B cell enhancing factor | 0.046 | 0.165 | 0.1447 |
Schistosoma mansoni | nicotinate phosphoribosyltransferase | 0.046 | 0.165 | 0.1447 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0157 | 0.0399 | 0.0399 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0162 | 0.0418 | 0.0186 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0157 | 0.0399 | 0.0399 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0157 | 0.0399 | 0.0399 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Leishmania major | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 1 |
Echinococcus granulosus | nicotinamide phosphoribosyltransferase | 0.248 | 1 | 1 |
Echinococcus multilocularis | G protein coupled receptor kinase 6 | 0.1039 | 0.4043 | 0.3898 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Mycobacterium tuberculosis | Nicotinic acid phosphoribosyltransferase PncB1 | 0.046 | 0.165 | 0.5 |
Echinococcus granulosus | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0157 | 0.0399 | 0.0399 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0157 | 0.0399 | 0.0166 |
Loa Loa (eye worm) | AGC/DMPK/ROCK protein kinase | 0.0465 | 0.1669 | 0.1669 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0157 | 0.0399 | 0.0399 |
Trichomonas vaginalis | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 1 |
Schistosoma mansoni | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Entamoeba histolytica | hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0157 | 0.0399 | 0.0166 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.1039 | 0.4043 | 0.4043 |
Loa Loa (eye worm) | RGS-3 protein | 0.0157 | 0.0399 | 0.0399 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1196 | 0.4693 | 0.4565 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.1039 | 0.4043 | 0.4043 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0157 | 0.0399 | 0.0166 |
Echinococcus multilocularis | rho associated protein kinase | 0.0153 | 0.0379 | 0.0145 |
Plasmodium falciparum | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Echinococcus multilocularis | expressed protein | 0.0157 | 0.0399 | 0.0166 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Brugia malayi | ribosomal protein S6 kinase alpha 3 | 0.009 | 0.012 | 0.012 |
Giardia lamblia | Kinase, AGC AKT | 0.009 | 0.012 | 0.5 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0162 | 0.0418 | 0.0186 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0157 | 0.0399 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Mycobacterium tuberculosis | Nicotinic acid phosphoribosyltransferase PncB2 | 0.046 | 0.165 | 0.5 |
Loa Loa (eye worm) | pre-B cell enhancing factor | 0.248 | 1 | 1 |
Trypanosoma brucei | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 1 |
Brugia malayi | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0162 | 0.0418 | 0.0186 |
Schistosoma mansoni | nicotinate phosphoribosyltransferase related pre-B cell enhancing factor | 0.248 | 1 | 1 |
Loa Loa (eye worm) | G protein-coupled receptor kinase 1 | 0.1039 | 0.4043 | 0.4043 |
Echinococcus granulosus | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0157 | 0.0399 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Brugia malayi | PXA domain containing protein | 0.0157 | 0.0399 | 0.0399 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0157 | 0.0399 | 0.0166 |
Entamoeba histolytica | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 1 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0157 | 0.0399 | 0.2418 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0162 | 0.0418 | 0.0418 |
Onchocerca volvulus | 0.0153 | 0.0379 | 1 | |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Brugia malayi | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Treponema pallidum | nicotinate phosphoribosyltransferase | 0.046 | 0.165 | 0.5 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0157 | 0.0399 | 0.0166 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0162 | 0.0418 | 0.0186 |
Echinococcus granulosus | expressed protein | 0.0157 | 0.0399 | 0.0166 |
Entamoeba histolytica | hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Brugia malayi | PXA domain containing protein | 0.0157 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0118 | 0.0237 | 0.0237 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0153 | 0.0379 | 0.0145 |
Toxoplasma gondii | AGC kinase | 0.0061 | 0 | 0.5 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0157 | 0.0399 | 0.0166 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.1196 | 0.4693 | 0.4693 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.1196 | 0.4693 | 0.4693 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Echinococcus granulosus | rho-associated protein kinase 1 | 0.0153 | 0.0379 | 0.0145 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Schistosoma mansoni | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | [G-protein-coupledreceptor] kinase | 0.1039 | 0.4043 | 0.3898 |
Echinococcus multilocularis | nicotinamide phosphoribosyltransferase | 0.248 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0157 | 0.0399 | 0.0166 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0157 | 0.0399 | 0.0399 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.