Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | nicotinate phosphoribosyltransferase | 0.046 | 0.165 | 0.5 |
Echinococcus granulosus | expressed protein | 0.0157 | 0.0399 | 0.0166 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Onchocerca volvulus | 0.0153 | 0.0379 | 1 | |
Echinococcus granulosus | [G-protein-coupledreceptor] kinase | 0.1039 | 0.4043 | 0.3898 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0157 | 0.0399 | 0.0166 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0162 | 0.0418 | 0.0418 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0157 | 0.0399 | 0.0399 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0162 | 0.0418 | 0.0186 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0153 | 0.0379 | 0.0145 |
Entamoeba histolytica | hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Brugia malayi | Protein kinase domain containing protein | 0.0465 | 0.1669 | 0.1669 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0157 | 0.0399 | 0.0166 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0157 | 0.0399 | 0.0399 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0157 | 0.0399 | 0.0166 |
Entamoeba histolytica | hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0118 | 0.0237 | 0.0237 |
Trichomonas vaginalis | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 1 |
Entamoeba histolytica | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 1 |
Brugia malayi | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0157 | 0.0399 | 0.0399 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | nicotinate phosphoribosyltransferase related pre-B cell enhancing factor | 0.046 | 0.165 | 0.1447 |
Loa Loa (eye worm) | RGS-3 protein | 0.0157 | 0.0399 | 0.0399 |
Brugia malayi | PXA domain containing protein | 0.0157 | 0.0399 | 0.0399 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.1039 | 0.4043 | 0.4043 |
Leishmania major | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 1 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0157 | 0.0399 | 0.0166 |
Brugia malayi | ribosomal protein S6 kinase alpha 3 | 0.009 | 0.012 | 0.012 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0157 | 0.0399 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.1039 | 0.4043 | 0.4043 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Schistosoma mansoni | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0157 | 0.0399 | 0.0399 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0157 | 0.0399 | 0.0399 |
Echinococcus multilocularis | rho associated protein kinase | 0.0153 | 0.0379 | 0.0145 |
Loa Loa (eye worm) | AGC/DMPK/ROCK protein kinase | 0.0465 | 0.1669 | 0.1669 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Trypanosoma cruzi | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1196 | 0.4693 | 0.4565 |
Schistosoma mansoni | nicotinate phosphoribosyltransferase related pre-B cell enhancing factor | 0.248 | 1 | 1 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | nicotinamide phosphoribosyltransferase | 0.248 | 1 | 1 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0157 | 0.0399 | 0.0166 |
Entamoeba histolytica | hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Trypanosoma brucei | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 1 |
Plasmodium falciparum | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 0.5 |
Loa Loa (eye worm) | G protein-coupled receptor kinase 1 | 0.1039 | 0.4043 | 0.4043 |
Mycobacterium tuberculosis | Nicotinic acid phosphoribosyltransferase PncB2 | 0.046 | 0.165 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Echinococcus multilocularis | expressed protein | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0162 | 0.0418 | 0.0186 |
Giardia lamblia | Kinase, AGC AKT | 0.009 | 0.012 | 0.5 |
Brugia malayi | PXA domain containing protein | 0.0157 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.1196 | 0.4693 | 0.4693 |
Loa Loa (eye worm) | pre-B cell enhancing factor | 0.248 | 1 | 1 |
Echinococcus multilocularis | G protein coupled receptor kinase 6 | 0.1039 | 0.4043 | 0.3898 |
Echinococcus multilocularis | nicotinamide phosphoribosyltransferase | 0.248 | 1 | 1 |
Mycobacterium tuberculosis | Nicotinic acid phosphoribosyltransferase PncB1 | 0.046 | 0.165 | 0.5 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0157 | 0.0399 | 0.0399 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | nicotinate phosphoribosyltransferase | 0.046 | 0.165 | 0.1447 |
Brugia malayi | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | rho-associated protein kinase 1 | 0.0153 | 0.0379 | 0.0145 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0157 | 0.0399 | 0.0399 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0157 | 0.0399 | 0.0166 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.1196 | 0.4693 | 0.4693 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0157 | 0.0399 | 0.2418 |
Echinococcus granulosus | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0162 | 0.0418 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Toxoplasma gondii | AGC kinase | 0.0061 | 0 | 0.5 |
Echinococcus granulosus | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0162 | 0.0418 | 0.0186 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0157 | 0.0399 | 0.0166 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.