Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0174 | 0.0959 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.0959 | 0.0959 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0174 | 0.0959 | 0.0565 |
Entamoeba histolytica | hypothetical protein | 0.0174 | 0.0959 | 1 |
Brugia malayi | PXA domain containing protein | 0.0174 | 0.0959 | 0.0959 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0174 | 0.0959 | 0.0959 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0174 | 0.0959 | 1 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0179 | 0.1004 | 0.1004 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0174 | 0.0959 | 1 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0174 | 0.0959 | 0.0565 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0174 | 0.0959 | 0.0959 |
Schistosoma mansoni | axis inhibition protein axin | 0.0174 | 0.0959 | 0.0476 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.0959 | 0.0959 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0174 | 0.0959 | 0.0476 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0174 | 0.0959 | 0.0565 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0174 | 0.0959 | 0.0565 |
Brugia malayi | Protein kinase domain containing protein | 0.0477 | 0.3577 | 0.3577 |
Schistosoma mansoni | regulator of G protein signaling | 0.0174 | 0.0959 | 0.0476 |
Brugia malayi | hypothetical protein | 0.0174 | 0.0959 | 0.0959 |
Loa Loa (eye worm) | RGS-3 protein | 0.0174 | 0.0959 | 0.0959 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0174 | 0.0959 | 0.0565 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0174 | 0.0959 | 0.0565 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0179 | 0.1004 | 0.0621 |
Toxoplasma gondii | AGC kinase | 0.0063 | 0 | 0.5 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0174 | 0.0959 | 0.0565 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0174 | 0.0959 | 0.0565 |
Giardia lamblia | Kinase, AGC AKT | 0.0092 | 0.0256 | 0.5 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0179 | 0.1004 | 0.0621 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0174 | 0.0959 | 0.0565 |
Entamoeba histolytica | hypothetical protein | 0.0174 | 0.0959 | 1 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0174 | 0.0959 | 0.0959 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0174 | 0.0959 | 0.0565 |
Brugia malayi | ribosomal protein S6 kinase alpha 3 | 0.0092 | 0.0256 | 0.0256 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0157 | 0.0812 | 0.0321 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0174 | 0.0959 | 0.0959 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0174 | 0.0959 | 0.0959 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.0959 | 0.0959 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0179 | 0.1004 | 0.0523 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0174 | 0.0959 | 0.0476 |
Echinococcus granulosus | axis inhibition protein axin | 0.0174 | 0.0959 | 0.0565 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0174 | 0.0959 | 0.0565 |
Echinococcus granulosus | axis inhibition protein axin | 0.0174 | 0.0959 | 0.0565 |
Echinococcus granulosus | rho-associated protein kinase 1 | 0.0157 | 0.0812 | 0.0381 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0174 | 0.0959 | 1 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0174 | 0.0959 | 0.0959 |
Leishmania major | rac serine-threonine kinase, putative,protein kinase, putative | 0.0092 | 0.0256 | 0.5 |
Onchocerca volvulus | 0.0157 | 0.0812 | 1 | |
Schistosoma mansoni | regulator of G protein signaling | 0.0174 | 0.0959 | 0.0476 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0174 | 0.0959 | 0.0476 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.0959 | 0.0959 |
Entamoeba histolytica | hypothetical protein | 0.0174 | 0.0959 | 1 |
Schistosoma mansoni | regulator of G protein signaling | 0.0174 | 0.0959 | 0.0476 |
Schistosoma mansoni | regulator of G protein signaling | 0.0174 | 0.0959 | 0.0476 |
Echinococcus granulosus | expressed protein | 0.0174 | 0.0959 | 0.0565 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0174 | 0.0959 | 0.0959 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.1047 | 0.8498 | 0.8498 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0122 | 0.0508 | 0.0508 |
Brugia malayi | hypothetical protein | 0.0174 | 0.0959 | 0.0959 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.0959 | 0.0959 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.0959 | 0.0959 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0063 | 0 | 0.5 |
Brugia malayi | PXA domain containing protein | 0.0174 | 0.0959 | 0.0959 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0174 | 0.0959 | 1 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.1047 | 0.8498 | 0.8498 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.1221 | 1 | 1 |
Schistosoma mansoni | axis inhibition protein axin | 0.0174 | 0.0959 | 0.0476 |
Echinococcus multilocularis | rho associated protein kinase | 0.0157 | 0.0812 | 0.0381 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1221 | 1 | 1 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0174 | 0.0959 | 0.0565 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0174 | 0.0959 | 1 |
Echinococcus multilocularis | expressed protein | 0.0174 | 0.0959 | 0.0565 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0174 | 0.0959 | 0.0565 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0174 | 0.0959 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0179 | 0.1004 | 0.0523 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0174 | 0.0959 | 0.0476 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0174 | 0.0959 | 0.0565 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0174 | 0.0959 | 0.0565 |
Schistosoma mansoni | regulator of G protein signaling | 0.0174 | 0.0959 | 0.0476 |
Loa Loa (eye worm) | G protein-coupled receptor kinase 1 | 0.1047 | 0.8498 | 0.8498 |
Echinococcus granulosus | [G-protein-coupledreceptor] kinase | 0.1047 | 0.8498 | 1 |
Echinococcus multilocularis | G protein coupled receptor kinase 6 | 0.1047 | 0.8498 | 1 |
Loa Loa (eye worm) | AGC/DMPK/ROCK protein kinase | 0.0477 | 0.3577 | 0.3577 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.