Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0157 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.1039 | 0.4043 | 0.4043 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Schistosoma mansoni | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Loa Loa (eye worm) | AGC/DMPK/ROCK protein kinase | 0.0465 | 0.1669 | 0.1669 |
Echinococcus multilocularis | rho associated protein kinase | 0.0153 | 0.0379 | 0.0145 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0157 | 0.0399 | 0.0399 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Brugia malayi | ribosomal protein S6 kinase alpha 3 | 0.009 | 0.012 | 0.012 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0157 | 0.0399 | 0.0166 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | nicotinate phosphoribosyltransferase related pre-B cell enhancing factor | 0.046 | 0.165 | 0.1447 |
Loa Loa (eye worm) | RGS-3 protein | 0.0157 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0157 | 0.0399 | 0.0399 |
Leishmania major | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 1 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.1039 | 0.4043 | 0.4043 |
Brugia malayi | PXA domain containing protein | 0.0157 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0118 | 0.0237 | 0.0237 |
Brugia malayi | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Trichomonas vaginalis | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 1 |
Entamoeba histolytica | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 1 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0157 | 0.0399 | 0.0166 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Entamoeba histolytica | hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0157 | 0.0399 | 0.0399 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0157 | 0.0399 | 0.0166 |
Entamoeba histolytica | hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0153 | 0.0379 | 0.0145 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0157 | 0.0399 | 0.0166 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Brugia malayi | Protein kinase domain containing protein | 0.0465 | 0.1669 | 0.1669 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0162 | 0.0418 | 0.0418 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0157 | 0.0399 | 0.0399 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0162 | 0.0418 | 0.0186 |
Treponema pallidum | nicotinate phosphoribosyltransferase | 0.046 | 0.165 | 0.5 |
Echinococcus granulosus | expressed protein | 0.0157 | 0.0399 | 0.0166 |
Onchocerca volvulus | 0.0153 | 0.0379 | 1 | |
Echinococcus granulosus | [G-protein-coupledreceptor] kinase | 0.1039 | 0.4043 | 0.3898 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0157 | 0.0399 | 0.0166 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Toxoplasma gondii | AGC kinase | 0.0061 | 0 | 0.5 |
Echinococcus granulosus | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0162 | 0.0418 | 0.0186 |
Echinococcus granulosus | axis inhibition protein axin | 0.0157 | 0.0399 | 0.0166 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.1196 | 0.4693 | 0.4693 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0157 | 0.0399 | 0.2418 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0162 | 0.0418 | 0.0186 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | nicotinate phosphoribosyltransferase | 0.046 | 0.165 | 0.1447 |
Brugia malayi | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | rho-associated protein kinase 1 | 0.0153 | 0.0379 | 0.0145 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0157 | 0.0399 | 0.0399 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0157 | 0.0399 | 0.0166 |
Mycobacterium tuberculosis | Nicotinic acid phosphoribosyltransferase PncB1 | 0.046 | 0.165 | 0.5 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0157 | 0.0399 | 0.0399 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.1196 | 0.4693 | 0.4693 |
Echinococcus multilocularis | G protein coupled receptor kinase 6 | 0.1039 | 0.4043 | 0.3898 |
Echinococcus multilocularis | nicotinamide phosphoribosyltransferase | 0.248 | 1 | 1 |
Loa Loa (eye worm) | pre-B cell enhancing factor | 0.248 | 1 | 1 |
Loa Loa (eye worm) | G protein-coupled receptor kinase 1 | 0.1039 | 0.4043 | 0.4043 |
Mycobacterium tuberculosis | Nicotinic acid phosphoribosyltransferase PncB2 | 0.046 | 0.165 | 0.5 |
Brugia malayi | PXA domain containing protein | 0.0157 | 0.0399 | 0.0399 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0162 | 0.0418 | 0.0186 |
Echinococcus multilocularis | expressed protein | 0.0157 | 0.0399 | 0.0166 |
Giardia lamblia | Kinase, AGC AKT | 0.009 | 0.012 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.0399 | 0.0399 |
Trypanosoma brucei | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 1 |
Schistosoma mansoni | regulator of G protein signaling | 0.0157 | 0.0399 | 0.0166 |
Plasmodium falciparum | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 0.5 |
Schistosoma mansoni | nicotinate phosphoribosyltransferase related pre-B cell enhancing factor | 0.248 | 1 | 1 |
Trypanosoma cruzi | nicotinate phosphoribosyltransferase, putative | 0.046 | 0.165 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1196 | 0.4693 | 0.4565 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0157 | 0.0399 | 0.0166 |
Echinococcus granulosus | nicotinamide phosphoribosyltransferase | 0.248 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0157 | 0.0399 | 0.2418 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0157 | 0.0399 | 0.0166 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.