Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0064 | 0.0147 |
Schistosoma mansoni | P2X receptor subunit | 0.1104 | 0.1775 | 0.1775 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1103 | 0.1774 | 0.4103 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0064 | 0.0064 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.2674 | 0.4324 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1103 | 0.1774 | 0.4103 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.1104 | 0.1775 | 0.4105 |
Echinococcus multilocularis | carbonic anhydrase | 0.1103 | 0.1774 | 0.4103 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.617 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0246 | 0.0569 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.1104 | 0.1775 | 0.4105 |
Echinococcus granulosus | twitchin | 0.0013 | 0.0004 | 0.001 |
Toxoplasma gondii | hypothetical protein | 0.1103 | 0.1774 | 0.5 |
Schistosoma mansoni | P2X receptor subunit | 0.1104 | 0.1775 | 0.1775 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.1104 | 0.1775 | 0.4105 |
Echinococcus granulosus | muscleblind protein | 0.0162 | 0.0246 | 0.0569 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0064 | 0.0064 |
Schistosoma mansoni | hypothetical protein | 0.1103 | 0.1774 | 0.1774 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.2674 | 0.4324 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.2674 | 0.4324 | 0.5 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.005 | 0.0064 | 0.0147 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1103 | 0.1774 | 0.1774 |
Brugia malayi | Muscleblind-like protein | 0.0162 | 0.0246 | 0.0569 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.005 | 0.0064 | 0.0064 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0064 | 0.0147 |
Echinococcus granulosus | neuroglian | 0.0013 | 0.0004 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.001 | 0.0022 |
Loa Loa (eye worm) | hypothetical protein | 0.1103 | 0.1774 | 0.4103 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.1104 | 0.1775 | 0.4105 |
Echinococcus multilocularis | carbonic anhydrase II | 0.2674 | 0.4324 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.2674 | 0.4324 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.1103 | 0.1774 | 0.4103 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.005 | 0.0064 | 0.0147 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1103 | 0.1774 | 0.1774 |
Schistosoma mansoni | carbonic anhydrase | 0.1103 | 0.1774 | 0.1774 |
Echinococcus granulosus | neurotracting:lsamp:neurotrimin:obcam | 0.0014 | 0.0005 | 0.0013 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0005 | 0.0013 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0162 | 0.0246 | 0.0569 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase CanB | 0.3502 | 0.5668 | 1 |
Echinococcus multilocularis | carbonic anhydrase | 0.1103 | 0.1774 | 0.4103 |
Echinococcus granulosus | carbonic anhydrase | 0.1103 | 0.1774 | 0.4103 |
Loa Loa (eye worm) | hypothetical protein | 0.1103 | 0.1774 | 0.4103 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.005 | 0.0064 | 0.0147 |
Echinococcus granulosus | carbonic anhydrase | 0.1103 | 0.1774 | 0.4103 |
Onchocerca volvulus | Tyrosine kinase homolog | 0.0155 | 0.0236 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.001 | 0.0022 |
Schistosoma mansoni | nephrin | 0.0013 | 0.0004 | 0.0004 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.1103 | 0.1774 | 0.4103 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.1104 | 0.1775 | 0.4105 |
Loa Loa (eye worm) | hypothetical protein | 0.1103 | 0.1774 | 0.4103 |
Mycobacterium ulcerans | carbonic anhydrase | 0.617 | 1 | 1 |
Schistosoma mansoni | carbonic anhydrase | 0.617 | 1 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.005 | 0.0064 | 0.0147 |
Leishmania major | carbonic anhydrase family protein, putative | 0.617 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0162 | 0.0246 | 0.0569 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.2674 | 0.4324 | 0.4324 |
Echinococcus granulosus | roundabout 2 | 0.0016 | 0.001 | 0.0022 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.2674 | 0.4324 | 0.4324 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.2674 | 0.4324 | 0.5 |
Plasmodium falciparum | carbonic anhydrase | 0.1103 | 0.1774 | 0.5 |
Echinococcus granulosus | carbonic anhydrase | 0.1103 | 0.1774 | 0.4103 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.2674 | 0.4324 | 0.5 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.2674 | 0.4324 | 1 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.1104 | 0.1775 | 0.4105 |
Loa Loa (eye worm) | TK/KIN16 protein kinase | 0.0166 | 0.0254 | 0.0586 |
Trichomonas vaginalis | conserved hypothetical protein | 0.2668 | 0.4315 | 0.5 |
Brugia malayi | Immunoglobulin I-set domain containing protein | 0.0166 | 0.0254 | 0.0586 |
Echinococcus multilocularis | carbonic anhydrase | 0.1103 | 0.1774 | 0.4103 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.1103 | 0.1774 | 0.4103 |
Echinococcus multilocularis | muscleblind protein | 0.0162 | 0.0246 | 0.0569 |
Echinococcus multilocularis | roundabout 2 | 0.0016 | 0.001 | 0.0022 |
Schistosoma mansoni | carbonic anhydrase-related | 0.1103 | 0.1774 | 0.1774 |
Schistosoma mansoni | P2X receptor subunit | 0.1104 | 0.1775 | 0.1775 |
Schistosoma mansoni | cell adhesion molecule | 0.0014 | 0.0005 | 0.0005 |
Echinococcus multilocularis | neuroglian | 0.0013 | 0.0004 | 0.001 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.1103 | 0.1774 | 0.4103 |
Schistosoma mansoni | P2X receptor subunit | 0.1104 | 0.1775 | 0.1775 |
Echinococcus granulosus | carbonic anhydrase II | 0.2674 | 0.4324 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.2668 | 0.4315 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.