Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | carnitine O-palmitoyltransferase II, putative | 0.1307 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.4333 | 1 | 1 |
Echinococcus multilocularis | carnitine O palmitoyltransferase 1, liver | 0.223 | 0.3052 | 1 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.223 | 0.3052 | 1 |
Leishmania major | choline/Carnitine o-acyltransferase-like protein | 0.223 | 0.3052 | 1 |
Echinococcus granulosus | carnitine O palmitoyltransferase 1 liver | 0.223 | 0.3052 | 1 |
Trypanosoma cruzi | choline/carnitine O-acyltransferase, putative | 0.223 | 0.3052 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
MIC (functional) | = 0.125 ug ml-1 | Antibacterial activity against enterotoxigenic Escherichia coli by disc diffusion method | ChEMBL. | 23933534 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.