Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | G protein coupled receptor kinase 6 | 0.1656 | 0.897 | 1 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0183 | 0.0701 | 0.0532 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0179 | 0.0179 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0183 | 0.0701 | 0.0782 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0183 | 0.0701 | 0.0532 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0012 | 0.0012 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0061 | 0.0012 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0701 | 0.0532 |
Brugia malayi | hypothetical protein | 0.0183 | 0.0701 | 0.0532 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0183 | 0.0701 | 0.0782 |
Schistosoma mansoni | axis inhibition protein axin | 0.0183 | 0.0701 | 0.0701 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0061 | 0.0012 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0012 | 0.5 |
Schistosoma mansoni | regulator of G protein signaling | 0.0183 | 0.0701 | 0.0701 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0179 | 0.02 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0183 | 0.0701 | 0.5 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0183 | 0.0701 | 0.0782 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0183 | 0.0701 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0179 | 0.02 |
Echinococcus granulosus | axis inhibition protein axin | 0.0183 | 0.0701 | 0.0782 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0183 | 0.0701 | 0.0701 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0188 | 0.0726 | 0.0726 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0183 | 0.0701 | 0.5 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0183 | 0.0701 | 0.0782 |
Schistosoma mansoni | regulator of G protein signaling | 0.0183 | 0.0701 | 0.0701 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0183 | 0.0701 | 0.0782 |
Schistosoma mansoni | axis inhibition protein axin | 0.0183 | 0.0701 | 0.0701 |
Loa Loa (eye worm) | G protein-coupled receptor kinase 1 | 0.1656 | 0.897 | 0.8951 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.1656 | 0.897 | 0.8951 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0188 | 0.0726 | 0.0726 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.1656 | 0.897 | 0.8951 |
Echinococcus granulosus | [G-protein-coupledreceptor] kinase | 0.1656 | 0.897 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0183 | 0.0701 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1839 | 1 | 1 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0183 | 0.0701 | 0.0701 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0012 | 0.5 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.1839 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0179 | 0.0179 |
Echinococcus granulosus | expressed protein | 0.0183 | 0.0701 | 0.0782 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0183 | 0.0701 | 0.0782 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0701 | 0.0532 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0183 | 0.0701 | 0.5 |
Schistosoma mansoni | regulator of G protein signaling | 0.0183 | 0.0701 | 0.0701 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0061 | 0.0012 | 0.0012 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.0061 | 0.0012 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0701 | 0.0532 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0183 | 0.0701 | 0.0701 |
Brugia malayi | hypothetical protein | 0.0183 | 0.0701 | 0.0532 |
Brugia malayi | PXA domain containing protein | 0.0183 | 0.0701 | 0.0532 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0188 | 0.0726 | 0.0809 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0183 | 0.0701 | 0.0782 |
Schistosoma mansoni | regulator of G protein signaling | 0.0183 | 0.0701 | 0.0701 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0183 | 0.0701 | 0.0782 |
Loa Loa (eye worm) | RGS-3 protein | 0.0183 | 0.0701 | 0.0532 |
Brugia malayi | PXA domain containing protein | 0.0183 | 0.0701 | 0.0532 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0183 | 0.0701 | 0.5 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0183 | 0.0701 | 0.0782 |
Echinococcus multilocularis | expressed protein | 0.0183 | 0.0701 | 0.0782 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0183 | 0.0701 | 0.0782 |
Entamoeba histolytica | hypothetical protein | 0.0183 | 0.0701 | 0.5 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0183 | 0.0701 | 0.0782 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0183 | 0.0701 | 0.0782 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0183 | 0.0701 | 0.0532 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0183 | 0.0701 | 0.5 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0183 | 0.0701 | 0.0532 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0188 | 0.0726 | 0.0557 |
Echinococcus granulosus | axis inhibition protein axin | 0.0183 | 0.0701 | 0.0782 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0061 | 0.0012 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.0179 | 0.02 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0701 | 0.0532 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0183 | 0.0701 | 0.5 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0183 | 0.0701 | 0.0532 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0183 | 0.0701 | 0.0532 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0183 | 0.0701 | 0.0532 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.0179 | 0.02 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0183 | 0.0701 | 0.0701 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0183 | 0.0701 | 0.0782 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.0179 | 0.0179 |
Entamoeba histolytica | hypothetical protein | 0.0183 | 0.0701 | 0.5 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.0061 | 0.0012 | 0.0014 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0701 | 0.0532 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0188 | 0.0726 | 0.0809 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0061 | 0.0012 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0183 | 0.0701 | 0.0532 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0183 | 0.0701 | 0.0782 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0183 | 0.0701 | 0.0782 |
Schistosoma mansoni | regulator of G protein signaling | 0.0183 | 0.0701 | 0.0701 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.