Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | G protein-coupled receptor kinase 1 | 0.1781 | 0.8979 | 0.8979 |
Loa Loa (eye worm) | RGS-3 protein | 0.0197 | 0.0788 | 0.0788 |
Echinococcus multilocularis | G protein coupled receptor kinase 6 | 0.1781 | 0.8979 | 1 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.0076 | 0.0085 |
Echinococcus granulosus | axis inhibition protein axin | 0.0197 | 0.0788 | 0.0877 |
Schistosoma mansoni | regulator of G protein signaling 3 rgs3 | 0.0197 | 0.0788 | 0.0788 |
Echinococcus granulosus | A kinase anchor protein 10 mitochondrial | 0.0197 | 0.0788 | 0.0877 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0076 | 0.5 |
Schistosoma mansoni | axis inhibition protein axin | 0.0197 | 0.0788 | 0.0788 |
Brugia malayi | regulator of G-protein signaling rgs-7 | 0.0197 | 0.0788 | 0.0788 |
Schistosoma mansoni | regulator of G protein signaling | 0.0197 | 0.0788 | 0.0788 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0197 | 0.0788 | 0.0877 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0197 | 0.0788 | 0.0877 |
Echinococcus granulosus | Regulator of G protein signaling 20 | 0.0197 | 0.0788 | 0.0877 |
Echinococcus multilocularis | beta adrenergic receptor kinase | 0.0202 | 0.0812 | 0.0904 |
Echinococcus multilocularis | regulator of G protein signaling 7 | 0.0197 | 0.0788 | 0.0877 |
Brugia malayi | Probable G protein-coupled receptor kinase F19C6.1, putative | 0.1781 | 0.8979 | 0.8979 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.0076 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0197 | 0.0788 | 0.5 |
Echinococcus multilocularis | regulator of G protein signaling | 0.0197 | 0.0788 | 0.0877 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.0788 | 0.0788 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0197 | 0.0788 | 0.0877 |
Brugia malayi | hypothetical protein | 0.0197 | 0.0788 | 0.0788 |
Echinococcus multilocularis | Regulator of G protein signaling 20 | 0.0197 | 0.0788 | 0.0877 |
Entamoeba histolytica | hypothetical protein | 0.0197 | 0.0788 | 0.5 |
Schistosoma mansoni | lipoxygenase | 0.0058 | 0.0066 | 0.0066 |
Schistosoma mansoni | axis inhibition protein axin | 0.0197 | 0.0788 | 0.0788 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.0788 | 0.0788 |
Echinococcus granulosus | expressed protein | 0.0197 | 0.0788 | 0.0877 |
Echinococcus multilocularis | expressed protein | 0.0197 | 0.0788 | 0.0877 |
Echinococcus multilocularis | arachidonate 5 lipoxygenase | 0.0058 | 0.0066 | 0.0073 |
Echinococcus granulosus | arachidonate 5 lipoxygenase | 0.0058 | 0.0066 | 0.0073 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.0788 | 0.0788 |
Schistosoma mansoni | regulator of G protein signaling | 0.0197 | 0.0788 | 0.0788 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.0788 | 0.0788 |
Brugia malayi | PXA domain containing protein | 0.0197 | 0.0788 | 0.0788 |
Echinococcus granulosus | axis inhibition protein axin | 0.0197 | 0.0788 | 0.0877 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0197 | 0.0788 | 0.0788 |
Loa Loa (eye worm) | G protein signaling regulator EGL-10 | 0.0197 | 0.0788 | 0.0788 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0197 | 0.0788 | 0.0788 |
Brugia malayi | regulator of G-protein signaling egl-10 | 0.0197 | 0.0788 | 0.0788 |
Loa Loa (eye worm) | AGC/GRK/BARK protein kinase | 0.0202 | 0.0812 | 0.0812 |
Echinococcus granulosus | [G-protein-coupledreceptor] kinase | 0.1781 | 0.8979 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.1979 | 1 | 1 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0197 | 0.0788 | 0.0877 |
Echinococcus granulosus | beta-adrenergic receptor kinase | 0.0202 | 0.0812 | 0.0904 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.0076 | 0.5 |
Echinococcus granulosus | regulator of G protein signaling 7 | 0.0197 | 0.0788 | 0.0877 |
Loa Loa (eye worm) | PXA domain-containing protein | 0.0197 | 0.0788 | 0.0788 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0197 | 0.0788 | 0.5 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.1781 | 0.8979 | 0.8979 |
Echinococcus multilocularis | A kinase anchor protein 10, mitochondrial | 0.0197 | 0.0788 | 0.0877 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0197 | 0.0788 | 0.5 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0197 | 0.0788 | 0.0877 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.0076 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.0788 | 0.0788 |
Echinococcus multilocularis | axis inhibition protein axin | 0.0197 | 0.0788 | 0.0877 |
Loa Loa (eye worm) | AGC/GRK/GRK protein kinase | 0.1979 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0202 | 0.0812 | 0.0812 |
Schistosoma mansoni | regulator of G protein signaling | 0.0197 | 0.0788 | 0.0788 |
Brugia malayi | Regulator of G protein signaling domain containing protein | 0.0197 | 0.0788 | 0.0788 |
Schistosoma mansoni | regulator of G protein signaling | 0.0197 | 0.0788 | 0.0788 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0076 | 0.0076 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0197 | 0.0788 | 0.5 |
Entamoeba histolytica | hypothetical protein | 0.0197 | 0.0788 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0197 | 0.0788 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.0076 | 0.0076 |
Schistosoma mansoni | z-protein (S1r protein) | 0.0197 | 0.0788 | 0.0788 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.0076 | 0.0085 |
Entamoeba histolytica | hypothetical protein | 0.0197 | 0.0788 | 0.5 |
Echinococcus multilocularis | regulator of G protein signaling 3 | 0.0197 | 0.0788 | 0.0877 |
Echinococcus granulosus | regulator of G protein signaling 3 | 0.0197 | 0.0788 | 0.0877 |
Schistosoma mansoni | regulator of G protein signaling 17 19 20 (rgs17 19 20) | 0.0197 | 0.0788 | 0.0788 |
Trichomonas vaginalis | regulator of G protein signaling 5, rgs5, putative | 0.0197 | 0.0788 | 0.5 |
Schistosoma mansoni | regulator of G protein signaling | 0.0197 | 0.0788 | 0.0788 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0076 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0202 | 0.0812 | 0.0812 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0197 | 0.0788 | 0.5 |
Brugia malayi | PXA domain containing protein | 0.0197 | 0.0788 | 0.0788 |
Brugia malayi | A-kinase anchor protein 10, precursor | 0.0197 | 0.0788 | 0.0788 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.0076 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0197 | 0.0788 | 0.0788 |
Brugia malayi | hypothetical protein | 0.0197 | 0.0788 | 0.0788 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.