Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | inositol transporter | 0.3618 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0 | 0.5 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.3618 | 1 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0276 | 0.0658 | 0.1168 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.029 | 0.0698 | 1 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.3618 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.0358 | 0.1296 |
Brugia malayi | Sodium:solute symporter family protein | 0.0923 | 0.2467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0923 | 0.2467 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0056 | 0.0044 | 0.0178 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.3618 | 1 | 1 |
Loa Loa (eye worm) | O-glycosyl hydrolase family 30 protein | 0.029 | 0.0698 | 0.2698 |
Brugia malayi | hypothetical protein | 0.0276 | 0.0658 | 0.2667 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.0658 | 0.2534 |
Echinococcus granulosus | solute carrier family 5 | 0.3618 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.029 | 0.0698 | 1 |
Echinococcus multilocularis | solute carrier family 5 | 0.3618 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0923 | 0.2467 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0169 | 0.0358 | 0.1296 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.0447 | 0.1027 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0923 | 0.2467 | 0.2467 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0169 | 0.0358 | 0.0358 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0923 | 0.2467 | 0.2467 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.029 | 0.0698 | 1 |
Schistosoma mansoni | high-affinity choline transporter | 0.0923 | 0.2467 | 0.2467 |
Brugia malayi | O-Glycosyl hydrolase family 30 protein | 0.029 | 0.0698 | 0.2827 |
Onchocerca volvulus | 0.0923 | 0.2467 | 1 | |
Onchocerca volvulus | Huntingtin homolog | 0.0276 | 0.0658 | 0.1168 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.0201 | 0.0447 | 0.1027 |
Brugia malayi | Muscleblind-like protein | 0.0169 | 0.0358 | 0.1451 |
Loa Loa (eye worm) | hypothetical protein | 0.0276 | 0.0658 | 0.2534 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.3618 | 1 | 1 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.029 | 0.0698 | 1 |
Schistosoma mansoni | sodium/solute symporter | 0.0923 | 0.2467 | 0.2467 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0 | 0.5 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0923 | 0.2467 | 0.2467 |
Brugia malayi | GH02984p | 0.0923 | 0.2467 | 1 |
Echinococcus granulosus | muscleblind protein | 0.0169 | 0.0358 | 0.0358 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0923 | 0.2467 | 0.2467 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.029 | 0.0698 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0 | 0.5 |
Trichomonas vaginalis | glucosylceramidase, putative | 0.029 | 0.0698 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0056 | 0.0044 | 0.0178 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0923 | 0.2467 | 0.5 |
Schistosoma mansoni | inositol transporter | 0.3618 | 1 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0041 | 0 | 0.5 |
Echinococcus multilocularis | muscleblind protein | 0.0169 | 0.0358 | 0.0358 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.